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Machine learning-enabled discovery and design of membrane-active peptides

Bioorganic & medicinal chemistry, 2018-06, Vol.26 (10), p.2708-2718

2018

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Mild hyperthermia triggered doxorubicin release from optimized stealth thermosensitive liposomes improves intratumoral drug delivery and efficacy

Journal of controlled release, 2013-06, Vol.168 (2), p.142-150

2013

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Improved intratumoral nanoparticle extravasation and penetration by mild hyperthermia

Journal of controlled release, 2013-04, Vol.167 (2), p.130-137

2013

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Chemokine CCL28 Is a Potent Therapeutic Agent for Oropharyngeal Candidiasis

Antimicrobial agents and chemotherapy, 2020-07, Vol.64 (8)

2020

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Targeted and heat-triggered doxorubicin delivery to tumors by dual targeted cationic thermosensitive liposomes

Journal of controlled release, 2014-12, Vol.195, p.37-48

2014

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Triggered content release from optimized stealth thermosensitive liposomes using mild hyperthermia

Journal of controlled release, 2010-04, Vol.143 (2), p.274-279

2010

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Discovery of 7-arylsulfonyl-1,2,3,4, 4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridines: Identification of a potent and selective 5-HT6 receptor antagonist showing activity in rat social recognition test

Bioorganic & medicinal chemistry letters, 2012-02, Vol.22 (3), p.1421-1426

2012

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Activation of the lung S1P(1) receptor reduces allergen-induced plasma leakage in mice

British journal of pharmacology, 2009-11, Vol.158 (5), p.1295

2009

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Novel brain penetrant benzofuropiperidine 5-HT6 receptor antagonists

Bioorganic & medicinal chemistry letters, 2012-01, Vol.22 (1), p.120-123

2012

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Influence of Dosing Schedule on Organ Exposure to Cyclosporin in Pediatric Hematopoietic Stem Cell Transplantation: Analysis with a PBPK Model

Pharmaceutical research, 2010-12, Vol.27 (12), p.2602-2613

2010

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Rottlerin inhibits multiple steps involved in insulin-induced glucose uptake in 3T3-L1 adipocytes

Biochemical pharmacology, 2004-07, Vol.68 (1), p.105-112

2004

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The secretory intestinal transport of some beta-lactam antibiotics and anionic compounds: a mechanism contributing to poor oral absorption

The Journal of pharmacology and experimental therapeutics, 1996-07, Vol.278 (1), p.205

1996

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Arteriolar changes in nitric oxide activity and sensitivity during the course of streptozotocin-induced diabetes

European journal of pharmacology, 2002-11, Vol.455 (1), p.43-51

2002

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Substance P mediates inflammatory oedema in acute pancreatitis via activation of the neurokinin‐1 receptor in rats and mice

British journal of pharmacology, 2000-06, Vol.130 (3), p.505-512

2000

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Synthesis and benzodiazepine binding activity of a series of novel [1,2,4]triazolo[1,5-c]quinazolin-5(6H)-ones

Journal of medicinal chemistry, 1991-01, Vol.34 (1), p.281-290

1991

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On the safety of a new generation of DSM Aspergillus niger enzyme production strains

Regulatory toxicology and pharmacology, 2003-08, Vol.38 (1), p.27-35

2003

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Pharmacokinetics of ketoprofen in rabbit after a single topical application

European journal of drug metabolism and pharmacokinetics, 2000-07, Vol.25 (3-4), p.227-230

2000

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Angiotensin converting enzyme inhibitors: 1,5-benzothiazepine derivatives

Journal of medicinal chemistry, 1985-10, Vol.28 (10), p.1517-1521

1985

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Neutral endopeptidase and alcohol consumption, experiments in neutral endopeptidase-deficient mice

European journal of pharmacology, 2000-06, Vol.397 (2), p.327-334

2000

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Immunotoxicity of aflatoxin B1: Impairment of the cell-mediated response to vaccine antigen and modulation of cytokine expression

Toxicology and applied pharmacology, 2008-09, Vol.231 (2), p.142-149

2008

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Localized neuropathic pain: an expert consensus on local treatments

Drug design, development and therapy, 2017-01, Vol.11, p.2709-2718

2017

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Convergent neural connectivity in motor impulsivity and high-fat food binge-like eating in male Sprague-Dawley rats

Neuropsychopharmacology (New York, N.Y.), 2019-09, Vol.44 (10), p.1752-1761

2019

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Structural Mapping of Adenosine Receptor Mutations: Ligand Binding and Signaling Mechanisms

Trends in pharmacological sciences (Regular ed.), 2018-01, Vol.39 (1), p.75-89

2018

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Individual Differences in Impulsive Action Reflect Variation in the Cortical Serotonin 5-HT2A Receptor System

Neuropsychopharmacology (New York, N.Y.), 2015-07, Vol.40 (8), p.1957-1968

2015

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Reactions of 1-Methyl-2-phenylindole with Malondialdehyde and 4-Hydroxyalkenals. Analytical Applications to a Colorimetric Assay of Lipid Peroxidation

Chemical research in toxicology, 1998-10, Vol.11 (10), p.1176-1183

1998

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Machine learning-enabled discovery and design of membrane-active peptides

Mild hyperthermia triggered doxorubicin release from optimized stealth thermosensitive liposomes improves intratumoral drug delivery and efficacy

Improved intratumoral nanoparticle extravasation and penetration by mild hyperthermia

Chemokine CCL28 Is a Potent Therapeutic Agent for Oropharyngeal Candidiasis

Targeted and heat-triggered doxorubicin delivery to tumors by dual targeted cationic thermosensitive liposomes

Triggered content release from optimized stealth thermosensitive liposomes using mild hyperthermia

Discovery of 7-arylsulfonyl-1,2,3,4, 4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridines: Identification of a potent and selective 5-HT6 receptor antagonist showing activity in rat social recognition test

Activation of the lung S1P(1) receptor reduces allergen-induced plasma leakage in mice

Novel brain penetrant benzofuropiperidine 5-HT6 receptor antagonists

Influence of Dosing Schedule on Organ Exposure to Cyclosporin in Pediatric Hematopoietic Stem Cell Transplantation: Analysis with a PBPK Model

Rottlerin inhibits multiple steps involved in insulin-induced glucose uptake in 3T3-L1 adipocytes

The secretory intestinal transport of some beta-lactam antibiotics and anionic compounds: a mechanism contributing to poor oral absorption

Arteriolar changes in nitric oxide activity and sensitivity during the course of streptozotocin-induced diabetes

Substance P mediates inflammatory oedema in acute pancreatitis via activation of the neurokinin‐1 receptor in rats and mice

Synthesis and benzodiazepine binding activity of a series of novel [1,2,4]triazolo[1,5-c]quinazolin-5(6H)-ones

On the safety of a new generation of DSM Aspergillus niger enzyme production strains

Pharmacokinetics of ketoprofen in rabbit after a single topical application

Angiotensin converting enzyme inhibitors: 1,5-benzothiazepine derivatives

Neutral endopeptidase and alcohol consumption, experiments in neutral endopeptidase-deficient mice

Immunotoxicity of aflatoxin B1: Impairment of the cell-mediated response to vaccine antigen and modulation of cytokine expression

Localized neuropathic pain: an expert consensus on local treatments

Convergent neural connectivity in motor impulsivity and high-fat food binge-like eating in male Sprague-Dawley rats

Structural Mapping of Adenosine Receptor Mutations: Ligand Binding and Signaling Mechanisms

Individual Differences in Impulsive Action Reflect Variation in the Cortical Serotonin 5-HT2A Receptor System

Reactions of 1-Methyl-2-phenylindole with Malondialdehyde and 4-Hydroxyalkenals. Analytical Applications to a Colorimetric Assay of Lipid Peroxidation

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