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Triptonide is a reversible non-hormonal male contraceptive agent in mice and non-human primates

Nature communications, 2021-02, Vol.12 (1), p.1253-14, Article 1253

2021

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Assessment of Mitochondrial Toxicity in Human Cells Treated with Tenofovir: Comparison with Other Nucleoside Reverse Transcriptase Inhibitors

Antimicrobial Agents and Chemotherapy, 2002-03, Vol.46 (3), p.716-723

2002

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Tenofovir alafenamide: A novel prodrug of tenofovir for the treatment of Human Immunodeficiency Virus

Antiviral research, 2016-01, Vol.125, p.63-70

2016

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Evaluation of Nucleoside Phosphonates and Their Analogs and Prodrugs for Inhibition of Orthopoxvirus Replication

Antimicrobial Agents and Chemotherapy, 2003-07, Vol.47 (7), p.2193-2198

2003

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Early nucleoside reverse transcriptase inhibitors for the treatment of HIV: A brief history of stavudine (D4T) and its comparison with other dideoxynucleosides

Antiviral research, 2010, Vol.85 (1), p.34-38

2010

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Tenofovir exhibits low cytotoxicity in various human cell types: comparison with other nucleoside reverse transcriptase inhibitors

Antiviral research, 2002-04, Vol.54 (1), p.37-45

2002

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Acyclic purine phosphonate analogs as antiviral agents. Synthesis and structure-activity relationships

Journal of medicinal chemistry, 1990-04, Vol.33 (4), p.1207-1213

1990

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Synthesis, Oral Bioavailability Determination, and in vitro Evaluation of Prodrugs of the Antiviral Agent 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA)

Journal of medicinal chemistry, 1994-06, Vol.37 (12), p.1857-1864

1994

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Synthesis and antiviral activity of methyl derivatives of 9-[2-(phosphonomethoxy)ethyl]guanine

Journal of medicinal chemistry, 1992-08, Vol.35 (16), p.2958-2969

1992

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Synthesis and antiviral activity of 2'-substituted 9-[2-(phosphonomethoxy)ethyl]guanine analogs

Journal of medicinal chemistry, 1993-09, Vol.36 (19), p.2726-2738

1993

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Distribution and metabolism of intravitreal cidofovir and cyclic HPMPC in rabbits

Current eye research, 1996-05, Vol.15 (5), p.569-576

1996

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Early nucleoside reverse transcriptase inhibitors for the treatment of HIV: A brief history of stavudine (D4T) and its comparison with other dideoxynucleosides: Twenty-five Years of Antiretroviral Drug Development: Progress and Prospects

Antiviral research, 2010, Vol.85 (1), p.34-38

2010

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A new class of acyclic phosphonate nucleotide analogs: Phosphonate isosteres of acyclovir and ganciclovir monophosphates as antiviral agents

Journal of medicinal chemistry, 1991-07, Vol.34 (7), p.2286-2294

1991

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Effect of Oral Probenecid Coadministration on the Chronic Toxicity and Pharmacokinetics of Intravenous Cidofovir in Cynomolgus Monkeys

Toxicological sciences, 1998-08, Vol.44 (2), p.97-106

1998

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1-(2,3-Dideoxy-.beta.-D-glycero-pent-2-enofuranosyl)thymine. A highly potent and selective anti-HIV agent

Journal of medicinal chemistry, 1989-02, Vol.32 (2), p.461-466

1989

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Actinomycin Biosynthesis by Protoplasts Derived from Streptomyces parvulus

Antimicrobial Agents and Chemotherapy, 1978-01, Vol.13 (1), p.104-114

1978

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Purification and characterization of kynurenine formamidase activities from Streptomyces parvulus

Canadian journal of microbiology, 1986-06, Vol.32 (6), p.465-472

1986

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Synthesis and antiviral activity of the nucleotide analog (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cystosine

Journal of medicinal chemistry, 1989-07, Vol.32 (7), p.1457-1463

1989

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SYNTHESIS AND IN VITRO ACTIVITY OF C-2 QUATERNARY HETEROCYCLIC ALKYLTHIO CARBAPENEMS

The Journal of Antibiotics, 1987/12/25, Vol.40(12), pp.1707-1715

1987

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Synthesis and in vitro activity of 1.beta.-methyl C-2 quaternary heterocyclic alkylthio carbapenems

Journal of medicinal chemistry, 1989-03, Vol.32 (3), p.601-604

1989

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A preclinical and clinical overview of the nucleotide-based antiviral agent cidofovir (HPMPC)

Advances in experimental medicine and biology, 1996, Vol.394, p.105

1996

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Prodrugs of 2’,3’-Didehydro-3’-deoxythymidine (D4T): Synthesis, Antiviral Activity, and Rapid Pharmacokinetic Evaluation

Journal of pharmaceutical sciences, 1994-03, Vol.83 (3), p.339-343

1994

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Biochemical Pharmacology of Acyclic Nucleotide Analogues

Annals of the New York Academy of Sciences, 1990, Vol.616 (1), p.398-407

1990

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Comparative Studies of 2′,3′-Didehydro-2′,3′-Dideoxythymidine (D4T) with other Pyrimidine Nucleoside Analogues

Annals of the New York Academy of Sciences, 1990, Vol.616 (1), p.22-28

1990

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Synthesis and Biological Activities of Phosphonylalkylpurine Derivatives

Nucleosides & nucleotides, 1989-01, Vol.8 (5-6), p.927-931

1989

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Triptonide is a reversible non-hormonal male contraceptive agent in mice and non-human primates

Assessment of Mitochondrial Toxicity in Human Cells Treated with Tenofovir: Comparison with Other Nucleoside Reverse Transcriptase Inhibitors

Tenofovir alafenamide: A novel prodrug of tenofovir for the treatment of Human Immunodeficiency Virus

Evaluation of Nucleoside Phosphonates and Their Analogs and Prodrugs for Inhibition of Orthopoxvirus Replication

Early nucleoside reverse transcriptase inhibitors for the treatment of HIV: A brief history of stavudine (D4T) and its comparison with other dideoxynucleosides

Tenofovir exhibits low cytotoxicity in various human cell types: comparison with other nucleoside reverse transcriptase inhibitors

Acyclic purine phosphonate analogs as antiviral agents. Synthesis and structure-activity relationships

Synthesis, Oral Bioavailability Determination, and in vitro Evaluation of Prodrugs of the Antiviral Agent 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA)

Synthesis and antiviral activity of methyl derivatives of 9-[2-(phosphonomethoxy)ethyl]guanine

Synthesis and antiviral activity of 2'-substituted 9-[2-(phosphonomethoxy)ethyl]guanine analogs

Distribution and metabolism of intravitreal cidofovir and cyclic HPMPC in rabbits

Early nucleoside reverse transcriptase inhibitors for the treatment of HIV: A brief history of stavudine (D4T) and its comparison with other dideoxynucleosides: Twenty-five Years of Antiretroviral Drug Development: Progress and Prospects

A new class of acyclic phosphonate nucleotide analogs: Phosphonate isosteres of acyclovir and ganciclovir monophosphates as antiviral agents

Effect of Oral Probenecid Coadministration on the Chronic Toxicity and Pharmacokinetics of Intravenous Cidofovir in Cynomolgus Monkeys

1-(2,3-Dideoxy-.beta.-D-glycero-pent-2-enofuranosyl)thymine. A highly potent and selective anti-HIV agent

Actinomycin Biosynthesis by Protoplasts Derived from Streptomyces parvulus

Purification and characterization of kynurenine formamidase activities from Streptomyces parvulus

Synthesis and antiviral activity of the nucleotide analog (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cystosine

SYNTHESIS AND IN VITRO ACTIVITY OF C-2 QUATERNARY HETEROCYCLIC ALKYLTHIO CARBAPENEMS

Synthesis and in vitro activity of 1.beta.-methyl C-2 quaternary heterocyclic alkylthio carbapenems

A preclinical and clinical overview of the nucleotide-based antiviral agent cidofovir (HPMPC)

Prodrugs of 2’,3’-Didehydro-3’-deoxythymidine (D4T): Synthesis, Antiviral Activity, and Rapid Pharmacokinetic Evaluation

Biochemical Pharmacology of Acyclic Nucleotide Analogues

Comparative Studies of 2′,3′-Didehydro-2′,3′-Dideoxythymidine (D4T) with other Pyrimidine Nucleoside Analogues

Synthesis and Biological Activities of Phosphonylalkylpurine Derivatives

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