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Validation and structural characterization of the LEDGF/p75-MLL interface as a new target for the treatment of MLL-dependent leukemia

Cancer research (Chicago, Ill.), 2014-09, Vol.74 (18), p.5139-5151

2014

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Molecular Mechanism of LEDGF/p75 Dimerization

Structure (London), 2020-12, Vol.28 (12), p.1288-1299.e7

2020

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Unlike Its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival

Cells (Basel, Switzerland), 2021-01, Vol.10 (1), p.192

2021

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Structure of the effector-binding domain of the arabinose repressor AraR from Bacillus subtilis

Acta crystallographica. Section D, Biological crystallography., 2012-02, Vol.68 (2), p.176-185

2012

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Sensitive quantification of fibroblast activation protein and high-throughput screening for inhibition by FDA-approved compounds

European journal of medicinal chemistry, 2024-10, Vol.280, p.116948, Article 116948

2024

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Only mothers feed mature offspring in European Ceratina bees

Insect science, 2021-10, Vol.28 (5), p.1468-1481

2021

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Diversity and phylogeny of Paradiplozoon species (Monogenea: Diplozoidae) parasitising endemic cyprinoids in the peri-Mediterranean area, with a description of three new Paradiplozoon species

Parasitology research (1987), 2021-02, Vol.120 (2), p.481-496

2021

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Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation

Proceedings of the National Academy of Sciences - PNAS, 2018-07, Vol.115 (30), p.E7053-E7062

2018

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Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif

Nature communications, 2015-08, Vol.6 (1), p.7968-7968, Article 7968

2015

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The TFIIS N-terminal domain (TND): a transcription assembly module at the interface of order and disorder

Biochemical Society transactions, 2023-02, Vol.51 (1), p.125-135

2023

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Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers

Nature structural & molecular biology, 2018-01, Vol.25 (1), p.61-72

2018

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Next-Generation Drugs and Probes for Chromatin Biology: From Targeted Protein Degradation to Phase Separation

Molecules (Basel, Switzerland), 2018-08, Vol.23 (8), p.1958

2018

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A ubiquitous disordered protein interaction module orchestrates transcription elongation

Science (American Association for the Advancement of Science), 2021-11, Vol.374 (6571), p.1113-1121

2021

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Synthesis and antimicrobial evaluation of new 2-substituted 5,7-di- tert-butylbenzoxazoles

Bioorganic & medicinal chemistry, 2006-09, Vol.14 (17), p.5850-5865

2006

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Interaction modules that impart specificity to disordered protein

Trends in biochemical sciences (Amsterdam. Regular ed.), 2023-05, Vol.48 (5), p.477-490

2023

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BET-independent MLV-based Vectors Target Away From Promoters and Regulatory Elements

Molecular therapy. Nucleic acids, 2014-07, Vol.3 (7), p.e179-e179, Article e179

2014

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Using graphs and charts in scientific figures

Trends in biochemical sciences (Amsterdam. Regular ed.), 2023-11, Vol.48 (11), p.913-916

2023

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SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7), p.983-996

2023

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Relocalization of PU.1 Underlies the On- and Off-Tumor Effects of SWI/SNF Blockade in AML

Blood, 2022-11, Vol.140 (Supplement 1), p.2242-2243

2022

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Reactivation of the G1 enhancer landscape underlies core circuitry addiction to SWI/SNF

Nucleic acids research, 2024-01, Vol.52 (1), p.4-21

2024

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Lessons Learned: HIV Points the Way Towards Precision Treatment of Mixed-Lineage Leukemia

Trends in pharmacological sciences (Regular ed.), 2016-08, Vol.37 (8), p.660-671

2016

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SERS spectroscopy with Ag colloids

Journal of molecular structure, 1997-06, Vol.408, p.149-154

1997

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Validation of the MLL-LEDGF/P75 interaction as a therapeutic target for mixed lineage leukemia

Experimental hematology, 2016-09, Vol.44 (9), p.S69-S69

2016

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Surface-Enhanced Raman Scattering (SERS) Spectroscopy with Borohydride-Reduced Silver Colloids: Controlling Adsorption of the Scattering Species by Surface Potential of Silver Colloid

Collection of Czechoslovak chemical communications, 1993-11, Vol.58 (11), p.2682-2694

1993

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Occurrence and fate of microplastics at two different drinking water treatment plants within a river catchment

The Science of the total environment, 2020-11, Vol.741, p.140236-140236, Article 140236

2020

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Validation and structural characterization of the LEDGF/p75-MLL interface as a new target for the treatment of MLL-dependent leukemia

Molecular Mechanism of LEDGF/p75 Dimerization

Unlike Its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival

Structure of the effector-binding domain of the arabinose repressor AraR from Bacillus subtilis

Sensitive quantification of fibroblast activation protein and high-throughput screening for inhibition by FDA-approved compounds

Only mothers feed mature offspring in European Ceratina bees

Diversity and phylogeny of Paradiplozoon species (Monogenea: Diplozoidae) parasitising endemic cyprinoids in the peri-Mediterranean area, with a description of three new Paradiplozoon species

Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation

Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif

The TFIIS N-terminal domain (TND): a transcription assembly module at the interface of order and disorder

Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers

Next-Generation Drugs and Probes for Chromatin Biology: From Targeted Protein Degradation to Phase Separation

A ubiquitous disordered protein interaction module orchestrates transcription elongation

Synthesis and antimicrobial evaluation of new 2-substituted 5,7-di- tert-butylbenzoxazoles

Interaction modules that impart specificity to disordered protein

BET-independent MLV-based Vectors Target Away From Promoters and Regulatory Elements

Using graphs and charts in scientific figures

SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia

Relocalization of PU.1 Underlies the On- and Off-Tumor Effects of SWI/SNF Blockade in AML

Reactivation of the G1 enhancer landscape underlies core circuitry addiction to SWI/SNF

Lessons Learned: HIV Points the Way Towards Precision Treatment of Mixed-Lineage Leukemia

SERS spectroscopy with Ag colloids

Validation of the MLL-LEDGF/P75 interaction as a therapeutic target for mixed lineage leukemia

Surface-Enhanced Raman Scattering (SERS) Spectroscopy with Borohydride-Reduced Silver Colloids: Controlling Adsorption of the Scattering Species by Surface Potential of Silver Colloid

Occurrence and fate of microplastics at two different drinking water treatment plants within a river catchment

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