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In-vitro mercaptopyruvate sulfurtransferase species comparison in humans and common laboratory animals

Toxicology letters, 2017-05, Vol.274, p.64-68

2017

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An Orally Bioavailable (Mice) Prodrug of Glutathione

Antioxidants, 2021-06, Vol.10 (6), p.939

2021

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Sequestration and Elimination of Toxic Aldehydes

Chemical research in toxicology, 2020-03, Vol.33 (3), p.764-768

2020

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Development of sulfanegen for mass cyanide casualties

Annals of the New York Academy of Sciences, 2016-06, Vol.1374 (1), p.202-209

2016

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Cyanide Antidotes for Mass Casualties: Water-Soluble Salts of the Dithiane (Sulfanegen) from 3‑Mercaptopyruvate for Intramuscular Administration

Journal of medicinal chemistry, 2013-02, Vol.56 (3), p.1346-1349

2013

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Cyanide Toxicity in Juvenile Pigs and Its Reversal by a New Prodrug, Sulfanegen Sodium

Anesthesia and analgesia, 2012-05, Vol.114 (5), p.956-961

2012

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Sulfanegen sodium treatment in a rabbit model of sub-lethal cyanide toxicity

Toxicology and applied pharmacology, 2010-11, Vol.248 (3), p.269-276

2010

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Novel, Orally Effective Cyanide Antidotes

Journal of medicinal chemistry, 2007-12, Vol.50 (26), p.6462-6464

2007

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Donors of HNO

Current topics in medicinal chemistry, 2005-01, Vol.5 (7), p.649-664

2005

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Reaction between S-Nitrosothiols and Thiols: Generation of Nitroxyl (HNO) and Subsequent Chemistry

Biochemistry (Easton), 1998-04, Vol.37 (16), p.5362-5371

1998

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The combination of cobinamide and sulfanegen is highly effective in mouse models of cyanide poisoning

Clinical toxicology (Philadelphia, Pa.), 2011-06, Vol.49 (5), p.366-373

2011

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Diverse antioxidants protect against acetaminophen hepatotoxicity

Journal of biochemical and molecular toxicology, 2005-01, Vol.18 (6), p.361-368

2005

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A novel paradigm for assessing efficacies of potential antidotes against neurotoxins in mice

Toxicology letters, 2007-12, Vol.175 (1), p.111-117

2007

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Prodrugs of nitroxyl as inhibitors of aldehyde dehydrogenase

Journal of medicinal chemistry, 1992-10, Vol.35 (20), p.3648-3652

1992

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Prodrugs of L-cysteine as protective agents against acetaminophen-induced hepatotoxicity. 2-(Polyhydroxyalkyl)- and 2-(polyacetoxyalkyl)thiazolidine-4(R)-carboxylic acids

Journal of medicinal chemistry, 1987-10, Vol.30 (10), p.1891-1896

1987

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Reaction of Nitric Oxide with the Free Sulfhydryl Group of Human Serum Albumin Yields a Sulfenic Acid and Nitrous Oxide

Biochemistry (Easton), 1995-09, Vol.34 (36), p.11494-11499

1995

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Glutathione monoethyl ester protects against glutathione deficiencies due to aging and acetaminophen in mice

Mechanisms of ageing and development, 2000-12, Vol.120 (1), p.127-139

2000

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2-Substituted thiazolidine-4(R)-carboxylic acids as prodrugs of L-cysteine. Protection of mice against acetaminophen hepatotoxicity

Journal of medicinal chemistry, 1984-05, Vol.27 (5), p.591-596

1984

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Hepatoprotection by L-cysteine-glutathione mixed disulfide, a sulfhydryl-modified prodrug of glutathione

Journal of biochemical and molecular toxicology, 2003, Vol.17 (2), p.95-97

2003

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Carbethoxylating Agents as Inhibitors of Aldehyde Dehydrogenase

Journal of medicinal chemistry, 1995-05, Vol.38 (11), p.1872-1876

1995

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Acetaminophen-induced suppression of hepatic AdoMet synthetase activity is attenuated by prodrugs of l-cysteine

Toxicology letters, 2002-06, Vol.132 (1), p.1-8

2002

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p-Aminophenol-induced hepatotoxicity in hamsters: Role of glutathione

Journal of biochemical and molecular toxicology, 2004, Vol.18 (3), p.154-161

2004

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N-Terminal Dipeptides of d(−)-Penicillamine as Sequestration Agents for Acetaldehyde

Journal of medicinal chemistry, 2000-03, Vol.43 (5), p.1029-1033

2000

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Effects of 2( RS)- n-propylthiazolidine-4( R)-carboxylic acid on extrahepatic sulfhydryl levels in mice treated with acetaminophen

Biochemical pharmacology, 2001-04, Vol.61 (7), p.925-931

2001

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Diethylcarbamoylating/Nitroxylating Agents as Dual Action Inhibitors of Aldehyde Dehydrogenase: A Disulfiram−Cyanamide Merger

Journal of medicinal chemistry, 1999-10, Vol.42 (20), p.4016-4020

1999

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In-vitro mercaptopyruvate sulfurtransferase species comparison in humans and common laboratory animals

An Orally Bioavailable (Mice) Prodrug of Glutathione

Sequestration and Elimination of Toxic Aldehydes

Development of sulfanegen for mass cyanide casualties

Cyanide Antidotes for Mass Casualties: Water-Soluble Salts of the Dithiane (Sulfanegen) from 3‑Mercaptopyruvate for Intramuscular Administration

Cyanide Toxicity in Juvenile Pigs and Its Reversal by a New Prodrug, Sulfanegen Sodium

Sulfanegen sodium treatment in a rabbit model of sub-lethal cyanide toxicity

Novel, Orally Effective Cyanide Antidotes

Donors of HNO

Reaction between S-Nitrosothiols and Thiols: Generation of Nitroxyl (HNO) and Subsequent Chemistry

The combination of cobinamide and sulfanegen is highly effective in mouse models of cyanide poisoning

Diverse antioxidants protect against acetaminophen hepatotoxicity

A novel paradigm for assessing efficacies of potential antidotes against neurotoxins in mice

Prodrugs of nitroxyl as inhibitors of aldehyde dehydrogenase

Prodrugs of L-cysteine as protective agents against acetaminophen-induced hepatotoxicity. 2-(Polyhydroxyalkyl)- and 2-(polyacetoxyalkyl)thiazolidine-4(R)-carboxylic acids

Reaction of Nitric Oxide with the Free Sulfhydryl Group of Human Serum Albumin Yields a Sulfenic Acid and Nitrous Oxide

Glutathione monoethyl ester protects against glutathione deficiencies due to aging and acetaminophen in mice

2-Substituted thiazolidine-4(R)-carboxylic acids as prodrugs of L-cysteine. Protection of mice against acetaminophen hepatotoxicity

Hepatoprotection by L-cysteine-glutathione mixed disulfide, a sulfhydryl-modified prodrug of glutathione

Carbethoxylating Agents as Inhibitors of Aldehyde Dehydrogenase

Acetaminophen-induced suppression of hepatic AdoMet synthetase activity is attenuated by prodrugs of l-cysteine

p-Aminophenol-induced hepatotoxicity in hamsters: Role of glutathione

N-Terminal Dipeptides of d(−)-Penicillamine as Sequestration Agents for Acetaldehyde

Effects of 2( RS)- n-propylthiazolidine-4( R)-carboxylic acid on extrahepatic sulfhydryl levels in mice treated with acetaminophen

Diethylcarbamoylating/Nitroxylating Agents as Dual Action Inhibitors of Aldehyde Dehydrogenase: A Disulfiram−Cyanamide Merger

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