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Are 1,4- and 1,5-Disubstituted 1,2,3-Triazoles Good Pharmacophoric Groups?

ChemMedChem, 2014-11, Vol.9 (11), p.2497-2508

2014

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New Hyaluronic Acid from Plant Origin to Improve Joint Protection—An In Vitro Study

International journal of molecular sciences, 2022-08, Vol.23 (15), p.8114

2022

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Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis

Nature communications, 2018-12, Vol.9 (1), p.5232-16, Article 5232

2018

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In vitro metabolism study of combretastatin A-4 in rat and human liver microsomes

Drug metabolism and disposition, 2007-12, Vol.35 (12), p.2252-2261

2007

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Biological effects of combined resveratrol and vitamin D3 on ovarian tissue

Journal of ovarian research, 2017-09, Vol.10 (1), p.61-14, Article 61

2017

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Metabolic Fate of the Isocyanide Moiety: Are Isocyanides Pharmacophore Groups Neglected by Medicinal Chemists?

Chemical research in toxicology, 2020-04, Vol.33 (4), p.955-966

2020

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An Unexpected Deuterium-Induced Metabolic Switch in Doxophylline

ACS medicinal chemistry letters, 2022-08, Vol.13 (8), p.1278-1285

2022

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Identification of the human UDP-glucuronosyltransferases involved in the glucuronidation of combretastatin A-4

Drug metabolism and disposition, 2010-07, Vol.38 (7), p.1141-1146

2010

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Correction to “An Unexpected Deuterium-Induced Metabolic Switch in Doxophylline”

ACS medicinal chemistry letters, 2023-12, Vol.14 (12), p.1891-1892

2023

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Troxerutin, a mixture of O-hydroxyethyl derivatives of the natural flavonoid rutin: Chemical stability and analytical aspects

Journal of pharmaceutical and biomedical analysis, 2018-02, Vol.150, p.248-257

2018

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Identification of potent triazolylpyridine nicotinamide phosphoribosyltransferase (NAMPT) inhibitors bearing a 1,2,3-triazole tail group

European journal of medicinal chemistry, 2019-11, Vol.181, p.111576-111576, Article 111576

2019

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Development and validation of a stability-indicating HPLC-UV method for the determination of Thiocolchicoside and its degradation products

Journal of pharmaceutical and biomedical analysis, 2017-01, Vol.132, p.66-71

2017

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Development and validation of a stability-indicating LC–UV method for the determination of pantethine and its degradation product based on a forced degradation study

Journal of pharmaceutical and biomedical analysis, 2014-08, Vol.97, p.141-150

2014

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New insights in the metabolism of oxybutynin: evidence of N-oxidation of propargylamine moiety and rearrangement to enaminoketone

Xenobiotica, 2018-05, Vol.48 (5), p.478-487

2018

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Forced degradation study of thiocolchicoside: Characterization of its degradation products

Journal of pharmaceutical and biomedical analysis, 2012-03, Vol.61, p.215-223

2012

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In vitro metabolic fate of alizapride: evidence for the formation of reactive metabolites based on liquid chromatography-tandem mass spectrometry

Journal of mass spectrometry., 2012-06, Vol.47 (6), p.737-750

2012

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Identification of a Potent Phosphoinositide 3‐Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs

ChemMedChem, 2017-09, Vol.12 (18), p.1542-1554

2017

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Semicarbazide Hydrochloride as Impurity in Drug Substances: a Validated LC-DAD-UV Method for Its Determination in Carbazochrome and Carbazochrome Sodium Sulfonate

Chromatographia, 2017-10, Vol.80 (10), p.1535-1544

2017

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Data on metabolic stability, aqueous solubility and CYP inhibition of novel triazole-based nicotinamide phosphoribosyltransferase (NAMPT) inhibitors

Data in brief, 2020-02, Vol.28, p.105034-105034, Article 105034

2020

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Development and validation of a solid-phase extraction and gas chromatography–tandem mass spectrometry method for the determination of isopropyl-9H-thioxanthen-9-one in carton packaged milk

Journal of Chromatography A, 2008-12, Vol.1214 (1), p.128-133

2008

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Metabolic fate of combretastatin A-1: LC-DAD-MS/MS investigation and biological evaluation of its reactive metabolites

Journal of pharmaceutical and biomedical analysis, 2013-05, Vol.78-79, p.233-242

2013

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A Concise Synthesis of Pyrazole Analogues of CombretastatinA1 as Potent Anti-Tubulin Agents

ChemMedChem, 2013-04, Vol.8 (4), p.633

2013

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New insights in oxybutynin chemical stability: Identification in transdermal patches of a new impurity arising from oxybutynin N-oxide rearrangement

European journal of pharmaceutical sciences, 2016-03, Vol.84, p.123-131

2016

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In vitro metabolism study of 2-isopropyl-9H-thioxanthen-9-one (2-ITX) in rat and human: evidence for the formation of an epoxide metabolite

Xenobiotica, 2011-03, Vol.41 (3), p.212-225

2011

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In vitro metabolism study of 2-isopropyl-9 H -thioxanthen-9-one (2-ITX) in rat and human: evidence for the formation of an epoxide metabolite

Xenobiotica, 2011-03, Vol.41 (3), p.212-225

2011

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Are 1,4- and 1,5-Disubstituted 1,2,3-Triazoles Good Pharmacophoric Groups?

New Hyaluronic Acid from Plant Origin to Improve Joint Protection—An In Vitro Study

Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis

In vitro metabolism study of combretastatin A-4 in rat and human liver microsomes

Biological effects of combined resveratrol and vitamin D3 on ovarian tissue

Metabolic Fate of the Isocyanide Moiety: Are Isocyanides Pharmacophore Groups Neglected by Medicinal Chemists?

An Unexpected Deuterium-Induced Metabolic Switch in Doxophylline

Identification of the human UDP-glucuronosyltransferases involved in the glucuronidation of combretastatin A-4

Correction to “An Unexpected Deuterium-Induced Metabolic Switch in Doxophylline”

Troxerutin, a mixture of O-hydroxyethyl derivatives of the natural flavonoid rutin: Chemical stability and analytical aspects

Identification of potent triazolylpyridine nicotinamide phosphoribosyltransferase (NAMPT) inhibitors bearing a 1,2,3-triazole tail group

Development and validation of a stability-indicating HPLC-UV method for the determination of Thiocolchicoside and its degradation products

Development and validation of a stability-indicating LC–UV method for the determination of pantethine and its degradation product based on a forced degradation study

New insights in the metabolism of oxybutynin: evidence of N-oxidation of propargylamine moiety and rearrangement to enaminoketone

Forced degradation study of thiocolchicoside: Characterization of its degradation products

In vitro metabolic fate of alizapride: evidence for the formation of reactive metabolites based on liquid chromatography-tandem mass spectrometry

Identification of a Potent Phosphoinositide 3‐Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs

Semicarbazide Hydrochloride as Impurity in Drug Substances: a Validated LC-DAD-UV Method for Its Determination in Carbazochrome and Carbazochrome Sodium Sulfonate

Data on metabolic stability, aqueous solubility and CYP inhibition of novel triazole-based nicotinamide phosphoribosyltransferase (NAMPT) inhibitors

Development and validation of a solid-phase extraction and gas chromatography–tandem mass spectrometry method for the determination of isopropyl-9H-thioxanthen-9-one in carton packaged milk

Metabolic fate of combretastatin A-1: LC-DAD-MS/MS investigation and biological evaluation of its reactive metabolites

A Concise Synthesis of Pyrazole Analogues of CombretastatinA1 as Potent Anti-Tubulin Agents

New insights in oxybutynin chemical stability: Identification in transdermal patches of a new impurity arising from oxybutynin N-oxide rearrangement

In vitro metabolism study of 2-isopropyl-9H-thioxanthen-9-one (2-ITX) in rat and human: evidence for the formation of an epoxide metabolite

In vitro metabolism study of 2-isopropyl-9 H -thioxanthen-9-one (2-ITX) in rat and human: evidence for the formation of an epoxide metabolite

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