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Structural characterization of bisretinoid A2E photocleavage products and implications for age-related macular degeneration

Proceedings of the National Academy of Sciences - PNAS, 2010-04, Vol.107 (16), p.7275-7280

2010

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Further Evidence that a Cell Wall Precursor [C55-MurNAc-(Peptide)-GlcNAc] Serves as an Acceptor in a Sorting Reaction

Journal of Bacteriology, 2002-04, Vol.184 (8), p.2141-2147

2002

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Septocylindrins A and B: Peptaibols Produced by the Terrestrial Fungus Septocylindrium sp. LL-Z1518

Journal of natural products (Washington, D.C.), 2007-03, Vol.70 (3), p.391-396

2007

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Activation Loop Phosphorylation Modulates Bruton’s Tyrosine Kinase (Btk) Kinase Domain Activity

Biochemistry (Easton), 2009-03, Vol.48 (9), p.2021-2032

2009

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2-(Quinazolin-4-ylamino)-[1,4]benzoquinones as Covalent-Binding, Irreversible Inhibitors of the Kinase Domain of Vascular Endothelial Growth Factor Receptor-2

Journal of medicinal chemistry, 2005-12, Vol.48 (24), p.7560-7581

2005

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Early discovery drug screening using mass spectrometry

Current topics in medicinal chemistry, 2002-01, Vol.2 (1), p.13-33

Siegel, Marshall M

2002

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FTMS structure elucidation of natural products: application to muraymycin antibiotics using ESI multi-CHEF SORI-CID FTMS(n), the top-down/bottom-up approach, and HPLC ESI capillary-skimmer CID FTMS

Analytical chemistry (Washington), 2003-06, Vol.75 (11), p.2730-2739

2003

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Isolation and Structural Elucidation of AC326-α, A New Member of the Moenomycin Group

The Journal of Antibiotics, 2000/02/25, Vol.53(2), pp.191-195

2000

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GPC spin column HPLC-ESI-MS methods for screening drugs noncovalently bound to proteins

Methods in molecular biology (Clifton, N.J.), 2009, Vol.572, p.231

Siegel, Marshall M

2009

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Mechanism of Inactivation of β-Lactamases by Novel 6-Methylidene Penems Elucidated Using Electrospray Ionization Mass Spectrometry

Journal of medicinal chemistry, 2004-07, Vol.47 (14), p.3674-3688

2004

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Flavins Inhibit Human Cytomegalovirus UL80 Protease via Disulfide Bond Formation

Biochemistry (Easton), 1996-05, Vol.35 (18), p.5847-5855

1996

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Inhibition of Human Cytomegalovirus UL80 Protease by Specific Intramolecular Disulfide Bond Formation

Biochemistry (Easton), 1996-05, Vol.35 (18), p.5838-5846

1996

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Septocylindrins A and B: Peptaibols Produced by the Terrestrial Fungus S eptocylindrium sp. LL-Z1518

Journal of natural products (Washington, D.C.), 2007-03, Vol.70 (3), p.391-396

2007

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Multiple Ion Isolation Applications in FT-ICR MS: Exact-Mass MS n Internal Calibration and Purification/Interrogation of Protein−Drug Complexes

Analytical chemistry (Washington), 2002-08, Vol.74 (15), p.3877-3886

2002

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FTMS Structure Elucidation of Natural Products: Application to Muraymycin Antibiotics Using ESI Multi-CHEF SORI-CID FTMS n , the Top-Down/Bottom-Up Approach, and HPLC ESI Capillary-Skimmer CID FTMS

Analytical chemistry (Washington), 2003-06, Vol.75 (11), p.2730-2739

2003

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Sulfinemycin, a New Anthelmintic Antibiotic: Fermentation, Isolation and Structure Determination

The Journal of Antibiotics, 1995/03/25, Vol.48(3), pp.282-285

1995

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Calicheamicins, a novel family of antitumor antibiotics. 4. Structure elucidation of calicheamicins .beta.1Br, .gamma.1Br, .alpha.2I, .alpha.3I, .beta.1I, .gamma.1I, and .delta.1I

Journal of the American Chemical Society, 1992-01, Vol.114 (3), p.985-997

1992

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PYRROINDOMYCINS, NOVEL ANTIBIOTICS PRODUCED BY Streptomyces rugosporus sp. LL-42D005: I. ISOLATION AND STRUCTURE DETERMINATION

The Journal of Antibiotics, 1994/11/25, Vol.47(11), pp.1250-1257

1994

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Calichemicins, a novel family of antitumor antibiotics. 1. Chemistry and partial structure of calichemicin .gamma.1I

Journal of the American Chemical Society, 1987-05, Vol.109 (11), p.3464-3466

1987

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Calichemicins, a novel family of antitumor antibiotics. 2. Chemistry and structure of calichemicin .gamma.1I

Journal of the American Chemical Society, 1987-05, Vol.109 (11), p.3466-3468

1987

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Mechanism of inhibition of the class A beta -lactamases PC1 and TEM-1 by tazobactam. Observation of reaction products by electrospray ionization mass spectrometry

The Journal of biological chemistry, 2000-09, Vol.275 (35), p.26674-26682

2000

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Drug Screening Using Gel Permeation Chromatography Spin Columns Coupled with ESI‐MS

Mass Spectrometry in Medicinal Chemistry, 2007, p.63-120

2007

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Thermospray mass spectrometer interface used as a flow reactor for in situ thermal degradation studies: applications to .beta.-lactam antibiotics

Analytical chemistry (Washington), 1987-04, Vol.59 (7), p.989-995

1987

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Mass‐Spectrometry‐Based Drug Screening Assays for Early Phases in Drug Discovery

Integrated Strategies for Drug Discovery Using Mass Spectrometry, 2005, p.27-70

2005

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Mass Spectrometry Based Assays for Drug Screening in the Early Phases of Drug Discovery

Frontiers in Medicinal Chemistry - Online, 2004-01, Vol.1 (1), p.273-292

Siegel, Marshall M.

2004

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Structural characterization of bisretinoid A2E photocleavage products and implications for age-related macular degeneration

Further Evidence that a Cell Wall Precursor [C55-MurNAc-(Peptide)-GlcNAc] Serves as an Acceptor in a Sorting Reaction

Septocylindrins A and B: Peptaibols Produced by the Terrestrial Fungus Septocylindrium sp. LL-Z1518

Activation Loop Phosphorylation Modulates Bruton’s Tyrosine Kinase (Btk) Kinase Domain Activity

2-(Quinazolin-4-ylamino)-[1,4]benzoquinones as Covalent-Binding, Irreversible Inhibitors of the Kinase Domain of Vascular Endothelial Growth Factor Receptor-2

Early discovery drug screening using mass spectrometry

FTMS structure elucidation of natural products: application to muraymycin antibiotics using ESI multi-CHEF SORI-CID FTMS(n), the top-down/bottom-up approach, and HPLC ESI capillary-skimmer CID FTMS

Isolation and Structural Elucidation of AC326-α, A New Member of the Moenomycin Group

GPC spin column HPLC-ESI-MS methods for screening drugs noncovalently bound to proteins

Mechanism of Inactivation of β-Lactamases by Novel 6-Methylidene Penems Elucidated Using Electrospray Ionization Mass Spectrometry

Flavins Inhibit Human Cytomegalovirus UL80 Protease via Disulfide Bond Formation

Inhibition of Human Cytomegalovirus UL80 Protease by Specific Intramolecular Disulfide Bond Formation

Septocylindrins A and B: Peptaibols Produced by the Terrestrial Fungus S eptocylindrium sp. LL-Z1518

Multiple Ion Isolation Applications in FT-ICR MS: Exact-Mass MS n Internal Calibration and Purification/Interrogation of Protein−Drug Complexes

FTMS Structure Elucidation of Natural Products: Application to Muraymycin Antibiotics Using ESI Multi-CHEF SORI-CID FTMS n , the Top-Down/Bottom-Up Approach, and HPLC ESI Capillary-Skimmer CID FTMS

Sulfinemycin, a New Anthelmintic Antibiotic: Fermentation, Isolation and Structure Determination

Calicheamicins, a novel family of antitumor antibiotics. 4. Structure elucidation of calicheamicins .beta.1Br, .gamma.1Br, .alpha.2I, .alpha.3I, .beta.1I, .gamma.1I, and .delta.1I

PYRROINDOMYCINS, NOVEL ANTIBIOTICS PRODUCED BY Streptomyces rugosporus sp. LL-42D005: I. ISOLATION AND STRUCTURE DETERMINATION

Calichemicins, a novel family of antitumor antibiotics. 1. Chemistry and partial structure of calichemicin .gamma.1I

Calichemicins, a novel family of antitumor antibiotics. 2. Chemistry and structure of calichemicin .gamma.1I

Mechanism of inhibition of the class A beta -lactamases PC1 and TEM-1 by tazobactam. Observation of reaction products by electrospray ionization mass spectrometry

Drug Screening Using Gel Permeation Chromatography Spin Columns Coupled with ESI‐MS

Thermospray mass spectrometer interface used as a flow reactor for in situ thermal degradation studies: applications to .beta.-lactam antibiotics

Mass‐Spectrometry‐Based Drug Screening Assays for Early Phases in Drug Discovery

Mass Spectrometry Based Assays for Drug Screening in the Early Phases of Drug Discovery

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