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Intercellular Spread of Protein Aggregates in Neurodegenerative Disease

Annual review of cell and developmental biology, 2018-10, Vol.34, p.545

2018

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Apolipoprotein E and Alzheimer's disease: the influence of apolipoprotein E on amyloid-β and other amyloidogenic proteins

Journal of lipid research, 2017-05, Vol.58 (5), p.824-836

2017

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Solving neurodegeneration: common mechanisms and strategies for new treatments

Molecular neurodegeneration, 2022-03, Vol.17 (1), p.23-23, Article 23

2022

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Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer's disease

PLoS biology, 2024-04, Vol.22 (4), p.e3002607-e3002607

2024

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HTRA1 disaggregates α-synuclein amyloid fibrils and converts them into non-toxic and seeding incompetent species

Nature communications, 2024-03, Vol.15 (1), p.2436-2436, Article 2436

2024

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Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

Experimental neurology, 2004-02, Vol.185 (2), p.232-240

2004

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Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels

BMC neurology, 2017-11, Vol.17 (1), p.198-198, Article 198

2017

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MAPT R406W increases tau T217 phosphorylation in absence of amyloid pathology

Annals of clinical and translational neurology, 2021-09, Vol.8 (9), p.1817-1830

2021

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Pleiotropic Effects of Variants in Dementia Genes in Parkinson Disease

Frontiers in neuroscience, 2018-04, Vol.12, p.230

2018

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TDP-43 dysfunction results in R-loop accumulation and DNA replication defects

Journal of cell science, 2020-10, Vol.133 (20)

2020

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Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease

Acta neuropathologica communications, 2020-11, Vol.8 (1), p.196-196, Article 196

2020

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Variants in GBA , SNCA , and MAPT influence Parkinson disease risk, age at onset, and progression

Neurobiology of aging, 2016-01, Vol.37, p.209.e1-209.e7

2016

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APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread

Cell, 2024-01, Vol.187 (2), p.428-445.e20

2024

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CSF tau microtubule-binding region identifies pathological changes in primary tauopathies

Nature medicine, 2022-12, Vol.28 (12), p.2547-2554

2022

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An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology

Neuron (Cambridge, Mass.), 2023-08, Vol.111 (15), p.2383-2398.e7

2023

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Parkinson disease and cognitive impairment: Five new things

Neurology. Clinical practice, 2016-10, Vol.6 (5), p.452-458

2016

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Neocortical Lewy Body Pathology Parallels Parkinson's Dementia, but Not Always

Annals of neurology, 2023-01, Vol.93 (1), p.184-195

2023

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Deletion of M1 Muscarinic Acetylcholine Receptors Increases Amyloid Pathology In Vitro and In Vivo

The Journal of neuroscience, 2010-03, Vol.30 (12), p.4190-4196

2010

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Pleiotropic effect of LRRK2 on Parkinson‐associated proteins and processing of pathological alpha‐synuclein in myeloid cells

Alzheimer's & dementia, 2022-12, Vol.18 (S4), p.n/a

2022

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Is Levodopa Response a Valid Indicator of Parkinson's Disease?

Movement disorders, 2021-04, Vol.36 (4), p.948-954

2021

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Astrocytic BMAL1 regulates protein aggregation in mouse models of alpha‐synuclein and tau pathology

Alzheimer's & dementia, 2021-12, Vol.17 (S2), p.e058631-n/a

2021

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Novel SGCE Mutation in a Patient With Myoclonus-Dystonia: A Case Report

Neurology. Genetics, 2024-04, Vol.10 (2), p.e200128-e200128

2024

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Resequencing analysis of five Mendelian genes and the top genes from genome-wide association studies in Parkinson's Disease

Molecular neurodegeneration, 2016-04, Vol.11 (29), p.29-29, Article 29

2016

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A Selective Allosteric Potentiator of the M1 Muscarinic Acetylcholine Receptor Increases Activity of Medial Prefrontal Cortical Neurons and Restores Impairments in Reversal Learning

The Journal of neuroscience, 2009-11, Vol.29 (45), p.14271-14286

2009

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A Subpopulation of Neuronal M4 Muscarinic Acetylcholine Receptors Plays a Critical Role in Modulating Dopamine-Dependent Behaviors

The Journal of neuroscience, 2010-02, Vol.30 (6), p.2396-2405

2010

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Intercellular Spread of Protein Aggregates in Neurodegenerative Disease

Apolipoprotein E and Alzheimer's disease: the influence of apolipoprotein E on amyloid-β and other amyloidogenic proteins

Solving neurodegeneration: common mechanisms and strategies for new treatments

Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer's disease

HTRA1 disaggregates α-synuclein amyloid fibrils and converts them into non-toxic and seeding incompetent species

Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels

MAPT R406W increases tau T217 phosphorylation in absence of amyloid pathology

Pleiotropic Effects of Variants in Dementia Genes in Parkinson Disease

TDP-43 dysfunction results in R-loop accumulation and DNA replication defects

Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease

Variants in GBA , SNCA , and MAPT influence Parkinson disease risk, age at onset, and progression

APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread

CSF tau microtubule-binding region identifies pathological changes in primary tauopathies

An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology

Parkinson disease and cognitive impairment: Five new things

Neocortical Lewy Body Pathology Parallels Parkinson's Dementia, but Not Always

Deletion of M1 Muscarinic Acetylcholine Receptors Increases Amyloid Pathology In Vitro and In Vivo

Pleiotropic effect of LRRK2 on Parkinson‐associated proteins and processing of pathological alpha‐synuclein in myeloid cells

Is Levodopa Response a Valid Indicator of Parkinson's Disease?

Astrocytic BMAL1 regulates protein aggregation in mouse models of alpha‐synuclein and tau pathology

Novel SGCE Mutation in a Patient With Myoclonus-Dystonia: A Case Report

Resequencing analysis of five Mendelian genes and the top genes from genome-wide association studies in Parkinson's Disease

A Selective Allosteric Potentiator of the M1 Muscarinic Acetylcholine Receptor Increases Activity of Medial Prefrontal Cortical Neurons and Restores Impairments in Reversal Learning

A Subpopulation of Neuronal M4 Muscarinic Acetylcholine Receptors Plays a Critical Role in Modulating Dopamine-Dependent Behaviors

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