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Valproate, in Combination with Pemetrexed and Cisplatin, Provides Additional Efficacy to the Treatment of Malignant Mesothelioma

Clinical cancer research, 2009-04, Vol.15 (8), p.2818-2828

2009

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Histone deacetylase–mediated transcriptional activation reduces proviral loads in HTLV-1–associated myelopathy/tropical spastic paraparesis patients

Blood, 2007-11, Vol.110 (10), p.3722-3728

2007

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Valproate activates bovine leukemia virus gene expression, triggers apoptosis, and induces leukemia/lymphoma regression in vivo

Proceedings of the National Academy of Sciences - PNAS, 2005-07, Vol.102 (29), p.10309-10314

2005

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SHANK3 overexpression causes manic―like behaviour with unique pharmacogenetic properties

Nature (London), 2013-11, Vol.503 (7474), p.72-77

2013

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Photo-uncaging of BODIPY oxime ester for histone deacetylases induced apoptosis in tumor cells

Chemical communications (Cambridge, England), 2019-12, Vol.55 (94), p.14162-14165

2019

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Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma

Clinical cancer research, 2012-01, Vol.18 (2), p.408-416

2012

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Oxytocin-Mediated GABA Inhibition During Delivery Attenuates Autism Pathogenesis in Rodent Offspring

Science (American Association for the Advancement of Science), 2014-02, Vol.343 (6171), p.675-679

2014

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Correction of Niemann-Pick type C1 trafficking and activity with the histone deacetylase inhibitor valproic acid

The Journal of biological chemistry, 2020-06, Vol.295 (23), p.8017-8035

2020

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Prescribing Practices of Valproic Acid for Agitation and Delirium in the Intensive Care Unit

The Annals of pharmacotherapy, 2021-03, Vol.55 (3), p.311-317

2021

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Induction of a CD8+ T-cell response to the MAGE cancer testis antigen by combined treatment with azacitidine and sodium valproate in patients with acute myeloid leukemia and myelodysplasia

Blood, 2010-09, Vol.116 (11), p.1908-1918

2010

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Targeting autophagy potentiates the apoptotic effect of histone deacetylase inhibitors in t(8;21) AML cells

Blood, 2013-10, Vol.122 (14), p.2467-2476

2013

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Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2

Nature biotechnology, 2008-11, Vol.26 (11), p.1269-1275

2008

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Phase 1/2 study of the combination of 5-aza-2′-deoxycytidine with valproic acid in patients with leukemia

Blood, 2006-11, Vol.108 (10), p.3271-3279

2006

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Targeted transcriptional activation of silent oct4 pluripotency gene by combining designer TALEs and inhibition of epigenetic modifiers

Nucleic acids research, 2012-07, Vol.40 (12), p.5368-5377

2012

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Highly efficient biallelic genome editing of human ES/iPS cells using a CRISPR/Cas9 or TALEN system

Nucleic acids research, 2017-05, Vol.45 (9), p.5198-5207

2017

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Valproic acid-induced changes of 4D nuclear morphology in astrocyte cells

Molecular biology of the cell, 2021-08, Vol.32 (18), p.1624-1633

2021

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Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models

Proceedings of the National Academy of Sciences - PNAS, 2009-12, Vol.106 (51), p.21819-21824

2009

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Acetylation stabilizes the signaling protein WISP2 by preventing its degradation to suppress the progression of acute myeloid leukemia

The Journal of biological chemistry, 2023-03, Vol.299 (3), p.102971-102971, Article 102971

2023

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Valproic acid induces aberrant development of striatal compartments and corticostriatal pathways in a mouse model of autism spectrum disorder

The FASEB journal, 2017-10, Vol.31 (10), p.4458-4471

2017

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The histone deacetylase inhibitor valproic acid attenuates phospholipase Cγ2 and IgE‐mediated mast cell activation

Journal of leukocyte biology, 2020-09, Vol.108 (3), p.859-866

2020

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HDACs link the DNA damage response, processing of double-strand breaks and autophagy

Nature (London), 2011-03, Vol.471 (7336), p.74-79

2011

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Histone Deacetylase Inhibition-Mediated Neuronal Differentiation of Multipotent Adult Neural Progenitor Cells

Proceedings of the National Academy of Sciences - PNAS, 2004-11, Vol.101 (47), p.16659-16664

2004

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Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon

Nature methods, 2009-05, Vol.6 (5), p.363-369

2009

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Histone deacetylase is a target of valproic acid-mediated cellular differentiation

Cancer research (Chicago, Ill.), 2004-02, Vol.64 (3), p.1079-1086

2004

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GANT61 and Valproic Acid Synergistically Inhibited Multiple Myeloma Cell Proliferation via Hedgehog Signaling Pathway

Medical science monitor, 2020-02, Vol.26, p.e920541-e920541-9

2020

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Valproate, in Combination with Pemetrexed and Cisplatin, Provides Additional Efficacy to the Treatment of Malignant Mesothelioma

Histone deacetylase–mediated transcriptional activation reduces proviral loads in HTLV-1–associated myelopathy/tropical spastic paraparesis patients

Valproate activates bovine leukemia virus gene expression, triggers apoptosis, and induces leukemia/lymphoma regression in vivo

SHANK3 overexpression causes manic―like behaviour with unique pharmacogenetic properties

Photo-uncaging of BODIPY oxime ester for histone deacetylases induced apoptosis in tumor cells

Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma

Oxytocin-Mediated GABA Inhibition During Delivery Attenuates Autism Pathogenesis in Rodent Offspring

Correction of Niemann-Pick type C1 trafficking and activity with the histone deacetylase inhibitor valproic acid

Prescribing Practices of Valproic Acid for Agitation and Delirium in the Intensive Care Unit

Induction of a CD8+ T-cell response to the MAGE cancer testis antigen by combined treatment with azacitidine and sodium valproate in patients with acute myeloid leukemia and myelodysplasia

Targeting autophagy potentiates the apoptotic effect of histone deacetylase inhibitors in t(8;21) AML cells

Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2

Phase 1/2 study of the combination of 5-aza-2′-deoxycytidine with valproic acid in patients with leukemia

Targeted transcriptional activation of silent oct4 pluripotency gene by combining designer TALEs and inhibition of epigenetic modifiers

Highly efficient biallelic genome editing of human ES/iPS cells using a CRISPR/Cas9 or TALEN system

Valproic acid-induced changes of 4D nuclear morphology in astrocyte cells

Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models

Acetylation stabilizes the signaling protein WISP2 by preventing its degradation to suppress the progression of acute myeloid leukemia

Valproic acid induces aberrant development of striatal compartments and corticostriatal pathways in a mouse model of autism spectrum disorder

The histone deacetylase inhibitor valproic acid attenuates phospholipase Cγ2 and IgE‐mediated mast cell activation

HDACs link the DNA damage response, processing of double-strand breaks and autophagy

Histone Deacetylase Inhibition-Mediated Neuronal Differentiation of Multipotent Adult Neural Progenitor Cells

Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon

Histone deacetylase is a target of valproic acid-mediated cellular differentiation

GANT61 and Valproic Acid Synergistically Inhibited Multiple Myeloma Cell Proliferation via Hedgehog Signaling Pathway

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