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Valproic acid use is associated with diminished risk of contracting COVID-19, and diminished disease severity: Epidemiologic and in vitro analysis reveal mechanistic insights

PloS one, 2024-08, Vol.19 (8), p.e0307154

2024

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Aprepitant’s roles in abating seizures, behavioral, and cognitive deficits in mice model of epilepsy

Epilepsy & behavior, 2024-10, Vol.159, p.110028, Article 110028

2024

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Adolescent treadmill exercise enhances hippocampal brain-derived neurotrophic factor (BDNF) expression and improves cognition in autism-modeled rats

Physiology & behavior, 2024-10, Vol.284, p.114638, Article 114638

2024

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MSC Exosomes Containing Valproic Acid Promote Wound Healing by Modulating Inflammation and Angiogenesis

Molecules (Basel, Switzerland), 2024-09, Vol.29 (17), p.4281

2024

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Comparative effect of atorvastatin and risperidone on modulation of TLR4/NF-κB/NOX-2 in a rat model of valproic acid-induced autism

Behavioral and brain functions, 2024-09, Vol.20 (1), p.26, Article 26

2024

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Biomimetic nanoparticles with enhanced rapamycin delivery for autism spectrum disorder treatment via autophagy activation and oxidative stress modulation

Theranostics, 2024-01, Vol.14 (11), p.4375-4392

2024

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Preconditioning of Human Umbilical Cord Mesenchymal Stem Cells with a Histone Deacetylase Inhibitor: Valproic Acid

Balkan medical journal, 2024-09, Vol.41 (5), p.369-376

2024

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Erroneous predictive coding across brain hierarchies in a non-human primate model of autism spectrum disorder

Communications biology, 2024-07, Vol.7 (1), p.851-16, Article 851

2024

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Delving into the Complexity of Valproate-Induced Autism Spectrum Disorder: The Use of Zebrafish Models

Cells (Basel, Switzerland), 2024-08, Vol.13 (16), p.1349

2024

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Upregulation of Transferrin Receptor 1 (TfR1) but Not Glucose Transporter 1 (GLUT1) or CD98hc at the Blood-Brain Barrier in Response to Valproic Acid

Cells (Basel, Switzerland), 2024-07, Vol.13 (14), p.1181

2024

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Saliva Versus Plasma Therapeutic Drug Monitoring of Valproic Acid in Jordanian Patients

Drug research, 2024-09, Vol.74 (7), p.314-324

2024

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Cenobamate as an Early Adjunctive Treatment in Drug-Resistant Focal-Onset Seizures: An Observational Cohort Study

CNS drugs, 2024-09, Vol.38 (9), p.733-742

2024

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UGT2B10 is the Major UDP-Glucuronosyltransferase 2B Isoform Involved in the Metabolism of Lamotrigine and is Implicated in the Drug-Drug Interaction with Valproic Acid

The AAPS journal, 2024-09, Vol.26 (6), p.107, Article 107

2024

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Inhibition of PLA2G4A attenuated valproic acid- induced lysosomal membrane permeabilization and restored impaired autophagic flux: Implications for hepatotoxicity

Biochemical pharmacology, 2024-09, Vol.227, p.116438, Article 116438

2024

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Melatonin prevents bone loss in osteoporotic rats with valproic acid treatment by anti-inflammatory and anti-oxidative stress

International immunopharmacology, 2024-11, Vol.141, p.112932, Article 112932

2024

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Design of experiment (DoE) of mucoadhesive valproic acid-loaded nanostructured lipid carriers (NLC) for potential nose-to-brain application

International journal of pharmaceutics, 2024-10, Vol.664, p.124631, Article 124631

2024

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Oral edaravone ameliorates behavioral deficits and pathologies in a valproic acid-induced rat model of autism spectrum disorder

Neuropharmacology, 2024-11, Vol.258, p.110089, Article 110089

2024

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Joint use of population pharmacokinetics and machine learning for prediction of valproic acid plasma concentration in elderly epileptic patients

European journal of pharmaceutical sciences, 2024-10, Vol.201, p.106876, Article 106876

2024

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TAAR1 and 5-HT1B receptor agonists attenuate autism-like irritability and aggression in rats prenatally exposed to valproic acid

Pharmacology, biochemistry and behavior, 2024-12, Vol.245, p.173862, Article 173862

2024

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Pharmacological intervention of behavioural traits and brain histopathology of prenatal valproic acid-induced mouse model of autism

PloS one, 2024-09, Vol.19 (9), p.e0308632

2024

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Identification of Blood Biomarkers Related to Energy Metabolism and Construction of Diagnostic Prediction Model Based on Three Independent Alzheimer's Disease Cohorts

Journal of Alzheimer's disease, 2024, Vol.100 (4), p.1261-1287

2024

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Successful Synergistic Use of Gabapentin With Other Antiepileptic Drugs in the Management of Lance-Adams Syndrome Complicated by Alcohol Withdrawal Seizures: A Case Report

Clinical neuropharmacology, 2024-07, Vol.47 (4), p.134

2024

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CHIR99021 and Brdu Are Critical in Chicken iPSC Reprogramming via Small-Molecule Screening

Genes, 2024-09, Vol.15 (9), p.1206

2024

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Caregiver Perspective of Benefits and Side Effects of Anti-Seizure Medications in CDKL5 Deficiency Disorder from an International Database

CNS drugs, 2024-09, Vol.38 (9), p.719-732

2024

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Women’s health in focus: Real-world data on valproate prescriptions during pregnancy – a cohort study in Catalonia (Spain)

BMJ open, 2024-08, Vol.14 (8), p.e085167

2024

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Valproic acid use is associated with diminished risk of contracting COVID-19, and diminished disease severity: Epidemiologic and in vitro analysis reveal mechanistic insights

Aprepitant’s roles in abating seizures, behavioral, and cognitive deficits in mice model of epilepsy

Adolescent treadmill exercise enhances hippocampal brain-derived neurotrophic factor (BDNF) expression and improves cognition in autism-modeled rats

MSC Exosomes Containing Valproic Acid Promote Wound Healing by Modulating Inflammation and Angiogenesis

Comparative effect of atorvastatin and risperidone on modulation of TLR4/NF-κB/NOX-2 in a rat model of valproic acid-induced autism

Biomimetic nanoparticles with enhanced rapamycin delivery for autism spectrum disorder treatment via autophagy activation and oxidative stress modulation

Preconditioning of Human Umbilical Cord Mesenchymal Stem Cells with a Histone Deacetylase Inhibitor: Valproic Acid

Erroneous predictive coding across brain hierarchies in a non-human primate model of autism spectrum disorder

Delving into the Complexity of Valproate-Induced Autism Spectrum Disorder: The Use of Zebrafish Models

Upregulation of Transferrin Receptor 1 (TfR1) but Not Glucose Transporter 1 (GLUT1) or CD98hc at the Blood-Brain Barrier in Response to Valproic Acid

Saliva Versus Plasma Therapeutic Drug Monitoring of Valproic Acid in Jordanian Patients

Cenobamate as an Early Adjunctive Treatment in Drug-Resistant Focal-Onset Seizures: An Observational Cohort Study

UGT2B10 is the Major UDP-Glucuronosyltransferase 2B Isoform Involved in the Metabolism of Lamotrigine and is Implicated in the Drug-Drug Interaction with Valproic Acid

Inhibition of PLA2G4A attenuated valproic acid- induced lysosomal membrane permeabilization and restored impaired autophagic flux: Implications for hepatotoxicity

Melatonin prevents bone loss in osteoporotic rats with valproic acid treatment by anti-inflammatory and anti-oxidative stress

Design of experiment (DoE) of mucoadhesive valproic acid-loaded nanostructured lipid carriers (NLC) for potential nose-to-brain application

Oral edaravone ameliorates behavioral deficits and pathologies in a valproic acid-induced rat model of autism spectrum disorder

Joint use of population pharmacokinetics and machine learning for prediction of valproic acid plasma concentration in elderly epileptic patients

TAAR1 and 5-HT1B receptor agonists attenuate autism-like irritability and aggression in rats prenatally exposed to valproic acid

Pharmacological intervention of behavioural traits and brain histopathology of prenatal valproic acid-induced mouse model of autism

Identification of Blood Biomarkers Related to Energy Metabolism and Construction of Diagnostic Prediction Model Based on Three Independent Alzheimer's Disease Cohorts

Successful Synergistic Use of Gabapentin With Other Antiepileptic Drugs in the Management of Lance-Adams Syndrome Complicated by Alcohol Withdrawal Seizures: A Case Report

CHIR99021 and Brdu Are Critical in Chicken iPSC Reprogramming via Small-Molecule Screening

Caregiver Perspective of Benefits and Side Effects of Anti-Seizure Medications in CDKL5 Deficiency Disorder from an International Database

Women’s health in focus: Real-world data on valproate prescriptions during pregnancy – a cohort study in Catalonia (Spain)

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