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Preclinical activity of nanoliposomal irinotecan is governed by tumor deposition and intratumor prodrug conversion

Cancer research (Chicago, Ill.), 2014-12, Vol.74 (23), p.7003-7013

2014

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Correlation between Ferumoxytol Uptake in Tumor Lesions by MRI and Response to Nanoliposomal Irinotecan in Patients with Advanced Solid Tumors: A Pilot Study

Clinical cancer research, 2017-07, Vol.23 (14), p.3638-3648

2017

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Augmenting Experimental Gastric Cancer Activity of Irinotecan through Liposomal Formulation and Antiangiogenic Combination Therapy

Molecular cancer therapeutics, 2022-07, Vol.21 (7), p.1149-1159

2022

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Impact of tumor HER2/ERBB2 expression level on HER2-targeted liposomal doxorubicin-mediated drug delivery: multiple low-affinity interactions lead to a threshold effect

Molecular cancer therapeutics, 2013-09, Vol.12 (9), p.1816-1828

2013

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Extended topoisomerase 1 inhibition through liposomal irinotecan results in improved efficacy over topotecan and irinotecan in models of small-cell lung cancer

Anti-cancer drugs, 2017-11, Vol.28 (10), p.1086-1096

2017

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HER2-targeted liposomal doxorubicin displays enhanced anti-tumorigenic effects without associated cardiotoxicity

Toxicology and applied pharmacology, 2012-07, Vol.262 (1), p.1-10

2012

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Correction to: Longitudinal PET Imaging to Monitor Treatment Efficacy by Liposomal Irinotecan in Orthotopic Patient-Derived Pancreatic Tumor Models of High and Low Hypoxia

Molecular imaging and biology, 2021-04, Vol.23 (2), p.299-299

2021

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Longitudinal PET Imaging to Monitor Treatment Efficacy by Liposomal Irinotecan in Orthotopic Patient-Derived Pancreatic Tumor Models of High and Low Hypoxia

Molecular imaging and biology, 2020-06, Vol.22 (3), p.653-664

2020

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Pretherapy Ferumoxytol-enhanced MRI to Predict Response to Liposomal Irinotecan in Metastatic Breast Cancer

Radiology. Imaging cancer, 2023-03, Vol.5 (2), p.e220022-e220022

2023

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Longitudinal tumor hypoxia imaging with [18F]FAZA-PET provides early prediction of nanoliposomal irinotecan (nal-IRI) treatment activity

EJNMMI research, 2015-12, Vol.5 (1), p.57-57, Article 57

2015

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An EGF receptor/Ral-GTPase signaling cascade regulates c-Src activity and substrate specificity

The EMBO journal, 2000-02, Vol.19 (4), p.623-630

2000

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Ras‐dependent and ‐independent regulation of reactive oxygen species by mitogenic growth factors and TGF‐β1

The FASEB journal, 2000-09, Vol.14 (12), p.1741-1748

2000

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Abstract 4830: Preclinical anti-tumor activity of nanoliposomal irinotecan (Nal-IRI, MM-398) + 5-FU + oxaliplatin in pancreatic cancer

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4830-4830

2016

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Abstract P5-01-06: Characterization of metastatic breast cancer lesions with ferumoxytol MRI and treatment response to MM-398, nanoliposomal irinotecan (nal-IRI)

Cancer research (Chicago, Ill.), 2015-05, Vol.75 (9_Supplement), p.P5-P5-01-06

2015

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Abstract CT224: Pilot study in patients with advanced solid tumors to evaluate feasibility of ferumoxytol (FMX) as tumor imaging agent prior to MM-398, a nanoliposomal irinotecan (nal-IRI)

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.CT224-CT224

2014

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Abstract C293: Irinotecan sucrosofate liposome injection, MM-398, demonstrates superior activity and control of hypoxia as measured through longitudinal imaging using [18F]FAZA PET compared to free irinotecan in a colon adenocarcinoma xenograft model

Molecular cancer therapeutics, 2013-11, Vol.12 (11_Supplement), p.C293-C293

2013

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Abstract C207: Identifying differential mechanisms of action for MM-398/PEP02, a novel nanotherapeutic encapsulation of irinotecan

Molecular cancer therapeutics, 2011-11, Vol.10 (11_Supplement), p.C207-C207

2011

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Neural cell adhesion molecules modulate tyrosine phosphorylation of tubulin in nerve growth cone membranes

Neuron (Cambridge, Mass.), 1992-05, Vol.8 (5), p.831-842

1992

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L1 and N‐CAM Antibodies Trigger Protein Phosphatase Activity in Growth Cone‐Enriched Membranes

Journal of neurochemistry, 1995-07, Vol.65 (1), p.84-95

1995

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267. Enhancement of T-Cell Immunity by CEA Delivery to Dendritic Cells with Adenovirus Retargeted Via sCAR-Fibritin-CD40L

Molecular therapy, 2004-05, Vol.9 (S1), p.S102-S103

2004

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Ras‐dependent and ‐independent regulation of reactive oxygen species by mitogenic growth factors and TGF‐β1

The FASEB journal, 2000-09, Vol.14 (12), p.1741-1748

2000

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Protein tyrosine phosphatases expressed in developing brain and retinal Müller glia

Brain research. Molecular brain research., 1995, Vol.28 (1), p.110-116

1995

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Tyrosine kinase pp60c-src in Nerve growth cones and developing brain: Topographical and functional analysis

NeuroProtocols (Orlando, Fla.), 1992-12, Vol.1 (3), p.224-231

1992

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Tyrosine kinase pp60 c-src in Nerve growth cones and developing brain: Topographical and functional analysis

NeuroProtocols (Orlando, Fla.), 1992, Vol.1 (3), p.224-231

1992

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Preclinical activity of nanoliposomal irinotecan is governed by tumor deposition and intratumor prodrug conversion

Correlation between Ferumoxytol Uptake in Tumor Lesions by MRI and Response to Nanoliposomal Irinotecan in Patients with Advanced Solid Tumors: A Pilot Study

Augmenting Experimental Gastric Cancer Activity of Irinotecan through Liposomal Formulation and Antiangiogenic Combination Therapy

Impact of tumor HER2/ERBB2 expression level on HER2-targeted liposomal doxorubicin-mediated drug delivery: multiple low-affinity interactions lead to a threshold effect

Extended topoisomerase 1 inhibition through liposomal irinotecan results in improved efficacy over topotecan and irinotecan in models of small-cell lung cancer

HER2-targeted liposomal doxorubicin displays enhanced anti-tumorigenic effects without associated cardiotoxicity

Correction to: Longitudinal PET Imaging to Monitor Treatment Efficacy by Liposomal Irinotecan in Orthotopic Patient-Derived Pancreatic Tumor Models of High and Low Hypoxia

Longitudinal PET Imaging to Monitor Treatment Efficacy by Liposomal Irinotecan in Orthotopic Patient-Derived Pancreatic Tumor Models of High and Low Hypoxia

Pretherapy Ferumoxytol-enhanced MRI to Predict Response to Liposomal Irinotecan in Metastatic Breast Cancer

Longitudinal tumor hypoxia imaging with [18F]FAZA-PET provides early prediction of nanoliposomal irinotecan (nal-IRI) treatment activity

An EGF receptor/Ral-GTPase signaling cascade regulates c-Src activity and substrate specificity

Ras‐dependent and ‐independent regulation of reactive oxygen species by mitogenic growth factors and TGF‐β1

Abstract 4830: Preclinical anti-tumor activity of nanoliposomal irinotecan (Nal-IRI, MM-398) + 5-FU + oxaliplatin in pancreatic cancer

Abstract P5-01-06: Characterization of metastatic breast cancer lesions with ferumoxytol MRI and treatment response to MM-398, nanoliposomal irinotecan (nal-IRI)

Abstract CT224: Pilot study in patients with advanced solid tumors to evaluate feasibility of ferumoxytol (FMX) as tumor imaging agent prior to MM-398, a nanoliposomal irinotecan (nal-IRI)

Abstract C293: Irinotecan sucrosofate liposome injection, MM-398, demonstrates superior activity and control of hypoxia as measured through longitudinal imaging using [18F]FAZA PET compared to free irinotecan in a colon adenocarcinoma xenograft model

Abstract C207: Identifying differential mechanisms of action for MM-398/PEP02, a novel nanotherapeutic encapsulation of irinotecan

Neural cell adhesion molecules modulate tyrosine phosphorylation of tubulin in nerve growth cone membranes

L1 and N‐CAM Antibodies Trigger Protein Phosphatase Activity in Growth Cone‐Enriched Membranes

267. Enhancement of T-Cell Immunity by CEA Delivery to Dendritic Cells with Adenovirus Retargeted Via sCAR-Fibritin-CD40L

Ras‐dependent and ‐independent regulation of reactive oxygen species by mitogenic growth factors and TGF‐β1

Protein tyrosine phosphatases expressed in developing brain and retinal Müller glia

Tyrosine kinase pp60c-src in Nerve growth cones and developing brain: Topographical and functional analysis

Tyrosine kinase pp60 c-src in Nerve growth cones and developing brain: Topographical and functional analysis

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