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Wilms' tumours: about tumour suppressor genes, an oncogene and a chameleon gene

Nature reviews. Cancer, 2011-02, Vol.11 (2), p.111-121

Huff, Vicki

2011

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A unique subset of low-risk Wilms tumors is characterized by loss of function of TRIM28 (KAP1), a gene critical in early renal development: A Children's Oncology Group study

PloS one, 2018-12, Vol.13 (12), p.e0208936-e0208936

2018

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Wilms tumor genetics: Mutations in WT1, WTX, and CTNNB1 account for only about one-third of tumors

Genes chromosomes & cancer, 2008-06, Vol.47 (6), p.461-470

2008

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The Wilms tumor gene, Wt1, is critical for mouse spermatogenesis via regulation of sertoli cell polarity and is associated with non-obstructive azoospermia in humans

PLoS genetics, 2013-08, Vol.9 (8), p.e1003645-e1003645

2013

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The Wilms Tumor Gene, Wt1, Is Required for Sox9 Expression and Maintenance of Tubular Architecture in the Developing Testis

Proceedings of the National Academy of Sciences - PNAS, 2006-08, Vol.103 (32), p.11987-11992

2006

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Clinically Relevant Subsets Identified by Gene Expression Patterns Support a Revised Ontogenic Model of Wilms Tumor: A Children's Oncology Group Study

Neoplasia (New York, N.Y.), 2012-08, Vol.14 (8), p.742-IN21

2012

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Nephron Progenitor But Not Stromal Progenitor Cells Give Rise to Wilms Tumors in Mouse Models with β-Catenin Activation or Wt1 Ablation and Igf2 Upregulation

Neoplasia (New York, N.Y.), 2016-02, Vol.18 (2), p.71-81

2016

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Ubiquitin specific protease 18 (Usp18) is a WT1 transcriptional target

Experimental cell research, 2013-03, Vol.319 (5), p.612-622

2013

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Identification of germline DICER1 mutations and loss of heterozygosity in familial Wilms tumour

Journal of medical genetics, 2016-06, Vol.53 (6), p.385-388

2016

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Wt1 negatively regulates beta-catenin signaling during testis development

Development (Cambridge), 2008-05, Vol.135 (10), p.1875-1885

2008

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Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylation

The Journal of clinical investigation, 2011-01, Vol.121 (1), p.174-183

2011

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Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models

The Journal of clinical investigation, 2010-11, Vol.120 (11), p.3940-3952

2010

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MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours

Nature communications, 2015-12, Vol.6 (1), p.10013, Article 10013

2015

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Frequent association of β-catenin and WT1 mutations in Wilms tumors

Cancer research (Chicago, Ill.), 2000-11, Vol.60 (22), p.6288-6292

2000

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The Wilms Tumor Gene, Wt1, Is Critical for Mouse Spermatogenesis via Regulation of Sertoli Cell Polarity and Is Associated with Non-Obstructive Azoospermia in Humans: e1003645

PLoS genetics, 2013-08, Vol.9 (8)

2013

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Upregulation of c-MYC in WT1-mutant tumors: assessment of WT1 putative transcriptional targets using cDNA microarray expression profiling of genetically defined Wilms' tumors

Oncogene, 2003-06, Vol.22 (24), p.3821-3826

2003

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Genome-wide loss of heterozygosity analysis of WT1-wild-type and WT1-mutant Wilms tumors

Genes chromosomes & cancer, 2005-06, Vol.43 (2), p.172-180

2005

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Linkage of familial Wilms' tumor predisposition to chromosome 19 and a two-locus model for the etiology of familial tumors

Cancer research (Chicago, Ill.), 1998-04, Vol.58 (7), p.1387-1390

1998

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Parental origin of WT1 mutations and mental retardation in WAGR syndrome

Nature genetics, 1994-09, Vol.8 (1), p.13-13

Huff, Vicki

1994

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Absence of PPP2R1A mutations in Wilms tumor

Oncogene, 2001-04, Vol.20 (16), p.2050-2054

2001

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Lack of linkage of familial Wilms' tumour to chromosomal band 11p13

Nature (London), 1988-11, Vol.336 (6197), p.377-378

1988

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Wilms' tumours: about tumour suppressor genes, an oncogene and a chameleon gene

A unique subset of low-risk Wilms tumors is characterized by loss of function of TRIM28 (KAP1), a gene critical in early renal development: A Children's Oncology Group study

Wilms tumor genetics: Mutations in WT1, WTX, and CTNNB1 account for only about one-third of tumors

The Wilms tumor gene, Wt1, is critical for mouse spermatogenesis via regulation of sertoli cell polarity and is associated with non-obstructive azoospermia in humans

The Wilms Tumor Gene, Wt1, Is Required for Sox9 Expression and Maintenance of Tubular Architecture in the Developing Testis

Clinically Relevant Subsets Identified by Gene Expression Patterns Support a Revised Ontogenic Model of Wilms Tumor: A Children's Oncology Group Study

Nephron Progenitor But Not Stromal Progenitor Cells Give Rise to Wilms Tumors in Mouse Models with β-Catenin Activation or Wt1 Ablation and Igf2 Upregulation

Ubiquitin specific protease 18 (Usp18) is a WT1 transcriptional target

A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor

Identification of germline DICER1 mutations and loss of heterozygosity in familial Wilms tumour

Recurrent DGCR8, DROSHA, and SIX Homeodomain Mutations in Favorable Histology Wilms Tumors

Wt1 negatively regulates beta-catenin signaling during testis development

Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylation

Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models

MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours

Frequent association of β-catenin and WT1 mutations in Wilms tumors

The Wilms Tumor Gene, Wt1, Is Critical for Mouse Spermatogenesis via Regulation of Sertoli Cell Polarity and Is Associated with Non-Obstructive Azoospermia in Humans: e1003645

Upregulation of c-MYC in WT1-mutant tumors: assessment of WT1 putative transcriptional targets using cDNA microarray expression profiling of genetically defined Wilms' tumors

Genome-wide loss of heterozygosity analysis of WT1-wild-type and WT1-mutant Wilms tumors

Linkage of familial Wilms' tumor predisposition to chromosome 19 and a two-locus model for the etiology of familial tumors

Parental origin of WT1 mutations and mental retardation in WAGR syndrome

Absence of PPP2R1A mutations in Wilms tumor

Lack of linkage of familial Wilms' tumour to chromosomal band 11p13

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