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Targetable Pathways in Advanced Bladder Cancer: FGFR Signaling

Cancers, 2021-09, Vol.13 (19), p.4891

2021

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Inhibition of the CCL2 receptor, CCR2, enhances tumor response to immune checkpoint therapy

Communications biology, 2020-11, Vol.3 (1), p.720-720, Article 720

2020

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Advances in bladder cancer biology and therapy

Nature reviews. Cancer, 2021-02, Vol.21 (2), p.104-121

2021

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Functional Impact of Chromatin Remodeling Gene Mutations and Predictive Signature for Therapeutic Response in Bladder Cancer

Molecular cancer research, 2018-01, Vol.16 (1), p.69-77

2018

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VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P2 in yeast and mouse

The EMBO journal, 2008-12, Vol.27 (24), p.3221-3234

2008

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CD24 expression is important in male urothelial tumorigenesis and metastasis in mice and is androgen regulated

Proceedings of the National Academy of Sciences - PNAS, 2012-12, Vol.109 (51), p.E3588-E3596

2012

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Vac14p-Fig4p complex acts independently of Vac7p and couples PI3,5P₂ synthesis and turnover

The Journal of cell biology, 2006-02, Vol.172 (5), p.693-704

2006

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Patient Mutation Directed shRNA Screen Uncovers Novel Bladder Tumor Growth Suppressors

Molecular cancer research, 2015-09, Vol.13 (9), p.1306-1315

2015

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Quantitative Analysis of Endocytosis and Turnover of Epidermal Growth Factor (EGF) and EGF Receptor

Current protocols in cell biology, 2010-03, Vol.46 (1), p.15.14.1-15.14.20

2010

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Phosphoinositide 5-Phosphatase Fig4p Is Required for both Acute Rise and Subsequent Fall in Stress-Induced Phosphatidylinositol 3,5-Bisphosphate Levels

Eukaryotic Cell, 2006-04, Vol.5 (4), p.723-731

2006

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Osmotic Stress-Induced increase of Phosphatidylinositol 3,5-Bisphosphate Requires Vac14p, an Activator of the Lipid Kinase Fab1p

The Journal of cell biology, 2002-03, Vol.156 (6), p.1015-1028

2002

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GON4L Drives Cancer Growth through a YY1-Androgen Receptor-CD24 Axis

Cancer research (Chicago, Ill.), 2016-09, Vol.76 (17), p.5175-5185

2016

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Nuclear CD24 Drives Tumor Growth and Is Predictive of Poor Patient Prognosis

Cancer research (Chicago, Ill.), 2017-09, Vol.77 (18), p.4858-4867

2017

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VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P 2 in yeast and mouse

The EMBO journal, 2008-12, Vol.27 (24), p.3221-3234

2008

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RNA interference screen identifies Usp18 as a regulator of epidermal growth factor receptor synthesis

Molecular biology of the cell, 2009-03, Vol.20 (6), p.1833-1844

2009

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KDM6A Depletion in Breast Epithelial Cells Leads to Reduced Sensitivity to Anticancer Agents and Increased TGFβ Activity

Molecular cancer research, 2022-04, Vol.20 (4), p.637-649

2022

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Targeting DDR2 enhances tumor response to anti-PD-1 immunotherapy

Science advances, 2019-02, Vol.5 (2), p.eaav2437-eaav2437

2019

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Two Distinct Regions in a Yeast Myosin-V Tail Domain Are Required for the Movement of Different Cargoes

The Journal of cell biology, 2000-08, Vol.150 (3), p.513-525

2000

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Role in Tumor Growth of a Glycogen Debranching Enzyme Lost in Glycogen Storage Disease

JNCI : Journal of the National Cancer Institute, 2014-04, Vol.106 (5), p.1

2014

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Recruitment of Uev1B to Hrs-containing endosomes and its effect on endosomal trafficking

Experimental cell research, 2010-08, Vol.316 (13), p.2136-2151

2010

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The Potential of Combination Therapies and Patient Stratification to Improve CCR2 Inhibition Therapeutics

Journal of Cellular Immunology, 2021-01, Vol.3 (3)

2021

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Abstract 3949: Characterization of MP1115; a new natural killer cell activator

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.3949-3949

2019

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Abstract IA10: Developing rational combination therapy with checkpoint inhibitors

Clinical cancer research, 2020-08, Vol.26 (15_Supplement), p.IA10-IA10

2020

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Abstract 4085: DDR2 inhibition enhances response to anti-PD-1 immunotherapy

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.4085-4085

2019

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Abstract 4691: Inhibition of ubiquitin specific protease Usp18 reduces cancer cell proliferation by down regulating multiple proto-oncogenes including EGFR

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.4691-4691

2011

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Targetable Pathways in Advanced Bladder Cancer: FGFR Signaling

Inhibition of the CCL2 receptor, CCR2, enhances tumor response to immune checkpoint therapy

Advances in bladder cancer biology and therapy

Functional Impact of Chromatin Remodeling Gene Mutations and Predictive Signature for Therapeutic Response in Bladder Cancer

VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P2 in yeast and mouse

CD24 expression is important in male urothelial tumorigenesis and metastasis in mice and is androgen regulated

Vac14p-Fig4p complex acts independently of Vac7p and couples PI3,5P₂ synthesis and turnover

Patient Mutation Directed shRNA Screen Uncovers Novel Bladder Tumor Growth Suppressors

Quantitative Analysis of Endocytosis and Turnover of Epidermal Growth Factor (EGF) and EGF Receptor

Phosphoinositide 5-Phosphatase Fig4p Is Required for both Acute Rise and Subsequent Fall in Stress-Induced Phosphatidylinositol 3,5-Bisphosphate Levels

Osmotic Stress-Induced increase of Phosphatidylinositol 3,5-Bisphosphate Requires Vac14p, an Activator of the Lipid Kinase Fab1p

GON4L Drives Cancer Growth through a YY1-Androgen Receptor-CD24 Axis

Nuclear CD24 Drives Tumor Growth and Is Predictive of Poor Patient Prognosis

VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P 2 in yeast and mouse

RNA interference screen identifies Usp18 as a regulator of epidermal growth factor receptor synthesis

KDM6A Depletion in Breast Epithelial Cells Leads to Reduced Sensitivity to Anticancer Agents and Increased TGFβ Activity

Targeting DDR2 enhances tumor response to anti-PD-1 immunotherapy

Two Distinct Regions in a Yeast Myosin-V Tail Domain Are Required for the Movement of Different Cargoes

Role in Tumor Growth of a Glycogen Debranching Enzyme Lost in Glycogen Storage Disease

Recruitment of Uev1B to Hrs-containing endosomes and its effect on endosomal trafficking

The Potential of Combination Therapies and Patient Stratification to Improve CCR2 Inhibition Therapeutics

Abstract 3949: Characterization of MP1115; a new natural killer cell activator

Abstract IA10: Developing rational combination therapy with checkpoint inhibitors

Abstract 4085: DDR2 inhibition enhances response to anti-PD-1 immunotherapy

Abstract 4691: Inhibition of ubiquitin specific protease Usp18 reduces cancer cell proliferation by down regulating multiple proto-oncogenes including EGFR

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