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Cell-type-specific need of Ddx3 and PACT for interferon induction by RNA viruses

Journal of virology, 2023-12, Vol.97 (12), p.e0130423-e0130423

2023

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Interferon induction by STING requires its translocation to the late endosomes

Traffic (Copenhagen, Denmark), 2023-12, Vol.24 (12), p.576-586

2023

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Ifit2 restricts murine coronavirus spread to the spinal cord white matter and its associated myelin pathology

Journal of virology, 2023-08, Vol.97 (8), p.e0074923-e0074923

2023

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Unexpected Need of the Epidermal Growth Factor Receptor Tyrosine Kinase Activity for Signaling by Intracellular Pattern Recognition Receptors of Nucleic Acids

Journal of interferon & cytokine research, 2023-05, Vol.43 (5), p.189

2023

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STAT2 hinders STING intracellular trafficking and reshapes its activation in response to DNA damage

Proceedings of the National Academy of Sciences - PNAS, 2023-04, Vol.120 (16), p.e2216953120-e2216953120

2023

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IFN-Induced Protein with Tetratricopeptide Repeats 2 Limits Autoimmune Inflammation by Regulating Myeloid Cell Activation and Metabolic Activity

The Journal of immunology (1950), 2023-03, Vol.210 (6), p.721-731

2023

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Intracranial delivery of antisense locked nucleic acids for silencing microRNAs in the mouse brain

STAR protocols, 2022-12, Vol.3 (4), p.101836-101836, Article 101836

2022

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IRF3 inhibits nuclear translocation of NF-κB to prevent viral inflammation

Proceedings of the National Academy of Sciences - PNAS, 2022-09, Vol.119 (37), p.e2121385119-e2121385119

2022

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The antiviral action of the RIG-I induced pathway of apoptosis (RIPA) is enhanced by its ability to degrade Otulin, which deubiquitinates IRF3

Cell death and differentiation, 2022-03, Vol.29 (3), p.504-513

2022

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Innate Immune Responses to Herpesvirus Infection

Cells (Basel, Switzerland), 2021-08, Vol.10 (8), p.2122

2021

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EGFR‐mediated tyrosine phosphorylation of STING determines its trafficking route and cellular innate immunity functions

The EMBO journal, 2020-11, Vol.39 (22), p.e104106-n/a

2020

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Relative Contributions of the cGAS-STING and TLR3 Signaling Pathways to Attenuation of Herpes Simplex Virus 1 Replication

Journal of virology, 2020-02, Vol.94 (6)

2020

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Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis

Nature communications, 2020-02, Vol.11 (1), p.900-15, Article 900

2020

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Lnc(ing) interferon production and action

Cell research, 2019-09, Vol.29 (9), p.690-691

2019

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TRAF4 binds to the juxtamembrane region of EGFR directly and promotes kinase activation

Proceedings of the National Academy of Sciences - PNAS, 2018-11, Vol.115 (45), p.11531-11536

2018

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Constitutively Bound EGFR-Mediated Tyrosine Phosphorylation of TLR9 Is Required for Its Ability To Signal

The Journal of immunology (1950), 2018-04, Vol.200 (8), p.2809-2818

2018

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Attenuation of cGAS‐STING signaling is mediated by a p62/SQSTM1‐dependent autophagy pathway activated by TBK1

The EMBO journal, 2018-04, Vol.37 (8), p.n/a

2018

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RIG-I-like receptor-induced IRF3 mediated pathway of apoptosis (RIPA): a new antiviral pathway

Protein & Cell, 2017-03, Vol.8 (3), p.165-168

2017

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Interferon Regulatory Factor 8 (IRF8) Impairs Induction of Interferon Induced with Tetratricopeptide Repeat Motif (IFIT) Gene Family Members

The Journal of biological chemistry, 2016-06, Vol.291 (26), p.13535-13545

2016

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Ubiquitination of the Transcription Factor IRF-3 Activates RIPA, the Apoptotic Pathway that Protects Mice from Viral Pathogenesis

Immunity (Cambridge, Mass.), 2016-05, Vol.44 (5), p.1151-1161

2016

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protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development

The FEBS journal, 2015-12, Vol.282 (24), p.4766-4781

2015

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No Love Lost Between Viruses and Interferons

Annual review of virology, 2015-11, Vol.2 (1), p.549-572

2015

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Regulation of PACT-Mediated Protein Kinase Activation by the OV20.0 Protein of Orf Virus

Journal of virology, 2015-11, Vol.89 (22), p.11619-11629

2015

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EGFR kinase activity is required for TLR4 signaling and the septic shock response

EMBO reports, 2015-11, Vol.16 (11), p.1535-1547

2015

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Cell-type-specific need of Ddx3 and PACT for interferon induction by RNA viruses

Interferon induction by STING requires its translocation to the late endosomes

Ifit2 restricts murine coronavirus spread to the spinal cord white matter and its associated myelin pathology

Unexpected Need of the Epidermal Growth Factor Receptor Tyrosine Kinase Activity for Signaling by Intracellular Pattern Recognition Receptors of Nucleic Acids

STAT2 hinders STING intracellular trafficking and reshapes its activation in response to DNA damage

IFN-Induced Protein with Tetratricopeptide Repeats 2 Limits Autoimmune Inflammation by Regulating Myeloid Cell Activation and Metabolic Activity

Intracranial delivery of antisense locked nucleic acids for silencing microRNAs in the mouse brain

IRF3 inhibits nuclear translocation of NF-κB to prevent viral inflammation

The antiviral action of the RIG-I induced pathway of apoptosis (RIPA) is enhanced by its ability to degrade Otulin, which deubiquitinates IRF3

Innate Immune Responses to Herpesvirus Infection

EGFR‐mediated tyrosine phosphorylation of STING determines its trafficking route and cellular innate immunity functions

PACT-mediated PKR activation acts as a hyperosmotic stress intensity sensor weakening osmoadaptation and enhancing inflammation

Relative Contributions of the cGAS-STING and TLR3 Signaling Pathways to Attenuation of Herpes Simplex Virus 1 Replication

Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis

Lnc(ing) interferon production and action

TRAF4 binds to the juxtamembrane region of EGFR directly and promotes kinase activation

Constitutively Bound EGFR-Mediated Tyrosine Phosphorylation of TLR9 Is Required for Its Ability To Signal

Attenuation of cGAS‐STING signaling is mediated by a p62/SQSTM1‐dependent autophagy pathway activated by TBK1

RIG-I-like receptor-induced IRF3 mediated pathway of apoptosis (RIPA): a new antiviral pathway

Interferon Regulatory Factor 8 (IRF8) Impairs Induction of Interferon Induced with Tetratricopeptide Repeat Motif (IFIT) Gene Family Members

Ubiquitination of the Transcription Factor IRF-3 Activates RIPA, the Apoptotic Pathway that Protects Mice from Viral Pathogenesis

protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development

No Love Lost Between Viruses and Interferons

Regulation of PACT-Mediated Protein Kinase Activation by the OV20.0 Protein of Orf Virus

EGFR kinase activity is required for TLR4 signaling and the septic shock response

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