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A Prominent Role of Interleukin-18 in Acetaminophen-Induced Liver Injury Advocates Its Blockage for Therapy of Hepatic Necroinflammation

Frontiers in immunology, 2018-02, Vol.9, p.161

2018

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IL-18/IL-18BP and IL-22/IL-22BP: Two interrelated couples with therapeutic potential

Cellular signalling, 2019-11, Vol.63, p.109388-109388, Article 109388

2019

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IL‐22 in tissue‐protective therapy

British journal of pharmacology, 2013-06, Vol.169 (4), p.761-771

2013

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Pro-Inflammatory Signaling by IL-10 and IL-22: Bad Habit Stirred Up by Interferons?

Frontiers in immunology, 2013-01, Vol.4, p.18-18

Mühl, Heiko

2013

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Epigenetic regulation by CpG methylation splits strong from retarded IFNγ-induced IL-18BP in epithelial versus monocytic cells

Biochimica et biophysica acta. Gene regulatory mechanisms, 2018-03, Vol.1861 (3), p.191-199

2018

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Inducible NO synthase and antibacterial host defence in times of Th17/Th22/T22 immunity

Cellular microbiology, 2011-03, Vol.13 (3), p.340-348

2011

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IFNα converts IL-22 into a cytokine efficiently activating STAT1 and its downstream targets

Biochemical pharmacology, 2013-02, Vol.85 (3), p.396-403

2013

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Systemic Anti-TNFα Treatment Restores Diabetes-Impaired Skin Repair in ob/ob Mice by Inactivation of Macrophages

Journal of investigative dermatology, 2007-09, Vol.127 (9), p.2259-2267

2007

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Interferon‐α curbs production of interleukin‐22 by human peripheral blood mononuclear cells exposed to live Borrelia burgdorferi

Journal of cellular and molecular medicine, 2015-10, Vol.19 (10), p.2507-2511

2015

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Molecular mechanisms of IL‐18BP regulation in DLD‐1 cells: pivotal direct action of the STAT1/GAS axis on the promoter level

Journal of cellular and molecular medicine, 2009-08, Vol.13 (8b), p.1987-1994

2009

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Interleukin-18 bioactivity: a novel target for immunopharmacological anti-inflammatory intervention

European journal of pharmacology, 2004-10, Vol.500 (1), p.63-71

2004

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Failure of interferon gamma to induce the anti-inflammatory interleukin 18 binding protein in familial hemophagocytosis

PloS one, 2010-01, Vol.5 (1), p.e8663-e8663

2010

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Genome-wide analysis displays marked induction of EBI3/IL-27B in IL-18-activated AML-derived KG1 cells: Critical role of two κB binding sites in the human EBI3 promotor

Molecular immunology, 2008-05, Vol.45 (10), p.2869-2880

2008

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Endothelial nitric oxide synthase: a determinant of TNFalpha production by human monocytes/macrophages

Biochemical and biophysical research communications, 2003-10, Vol.310 (3), p.677-680

2003

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Endothelial nitric oxide synthase: a determinant of TNFα production by human monocytes/macrophages

Biochemical and biophysical research communications, 2003-10, Vol.310 (3), p.677-680

2003

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Controlling the cytokine storm by insulin: Glycogen synthase kinase-3 as a target in systemic inflammation

Critical care medicine, 2006-05, Vol.34 (5), p.1567-1569

2006

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Systematic analysis highlights the key role of TLR2/NF-κB/MAP kinase signaling for IL-8 induction by macrophage-like THP-1 cells under influence of Borrelia burgdorferi lysates

The international journal of biochemistry & cell biology, 2008, Vol.40 (11), p.2508-2521

2008

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IL-18 initiates release of matrix metalloproteinase-9 from peripheral blood mononuclear cells without affecting tissue inhibitor of matrix metalloproteinases-1: suppression by TNF alpha blockage and modulation by IL-10

Naunyn-Schmiedeberg's archives of pharmacology, 2003-01, Vol.367 (1), p.68-75

2003

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Immunopharmacology: anti-inflammatory therapy targeting transcription factors

European Journal of Pharmacology, 1999-06, Vol.375 (1), p.237-245

1999

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Inhibition of lipopolysaccharide/ATP-induced release of interleukin-18 by KN-62 and glyburide

European journal of pharmacology, 2003-12, Vol.482 (1), p.325-328

2003

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Expression and release of chemokines associated with apoptotic cell death in human promonocytic U937 cells and peripheral blood mononuclear cells

European journal of immunology, 1999-10, Vol.29 (10), p.3225-3235

1999

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Nitric oxide augments release of chemokines from monocytic U937 cells: modulation by anti-inflammatory pathways

Free radical biology & medicine, 2000-11, Vol.29 (10), p.969-980

2000

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Systemic anti-TNFalpha treatment restores diabetes-impaired skin repair in ob/ob mice by inactivation of macrophages

Journal of investigative dermatology, 2007-09, Vol.127 (9), p.2259-2267

2007

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Transforming growth factors type‐β and dexamethasone attenuate group II phospholipase A2 gene expression by interleukin‐1 and forskolin in rat mesangial cells

FEBS letters, 1992-04, Vol.301 (2), p.190-194

1992

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A Prominent Role of Interleukin-18 in Acetaminophen-Induced Liver Injury Advocates Its Blockage for Therapy of Hepatic Necroinflammation

IL-18/IL-18BP and IL-22/IL-22BP: Two interrelated couples with therapeutic potential

IL‐22 in tissue‐protective therapy

Pro-Inflammatory Signaling by IL-10 and IL-22: Bad Habit Stirred Up by Interferons?

Epigenetic regulation by CpG methylation splits strong from retarded IFNγ-induced IL-18BP in epithelial versus monocytic cells

Inducible NO synthase and antibacterial host defence in times of Th17/Th22/T22 immunity

IFNα converts IL-22 into a cytokine efficiently activating STAT1 and its downstream targets

Systemic Anti-TNFα Treatment Restores Diabetes-Impaired Skin Repair in ob/ob Mice by Inactivation of Macrophages

Interferon‐α curbs production of interleukin‐22 by human peripheral blood mononuclear cells exposed to live Borrelia burgdorferi

Molecular mechanisms of IL‐18BP regulation in DLD‐1 cells: pivotal direct action of the STAT1/GAS axis on the promoter level

Interleukin-18 bioactivity: a novel target for immunopharmacological anti-inflammatory intervention

Failure of interferon gamma to induce the anti-inflammatory interleukin 18 binding protein in familial hemophagocytosis

Genome-wide analysis displays marked induction of EBI3/IL-27B in IL-18-activated AML-derived KG1 cells: Critical role of two κB binding sites in the human EBI3 promotor

Endothelial nitric oxide synthase: a determinant of TNFalpha production by human monocytes/macrophages

Endothelial nitric oxide synthase: a determinant of TNFα production by human monocytes/macrophages

Controlling the cytokine storm by insulin: Glycogen synthase kinase-3 as a target in systemic inflammation

Systematic analysis highlights the key role of TLR2/NF-κB/MAP kinase signaling for IL-8 induction by macrophage-like THP-1 cells under influence of Borrelia burgdorferi lysates

IL-18 initiates release of matrix metalloproteinase-9 from peripheral blood mononuclear cells without affecting tissue inhibitor of matrix metalloproteinases-1: suppression by TNF alpha blockage and modulation by IL-10

Immunopharmacology: anti-inflammatory therapy targeting transcription factors

Inhibition of lipopolysaccharide/ATP-induced release of interleukin-18 by KN-62 and glyburide

Expression and release of chemokines associated with apoptotic cell death in human promonocytic U937 cells and peripheral blood mononuclear cells

Nitric oxide augments release of chemokines from monocytic U937 cells: modulation by anti-inflammatory pathways

Systemic anti-TNFalpha treatment restores diabetes-impaired skin repair in ob/ob mice by inactivation of macrophages

Transforming growth factors type‐β and dexamethasone attenuate group II phospholipase A2 gene expression by interleukin‐1 and forskolin in rat mesangial cells

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