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A Prominent Role of Interleukin-18 in Acetaminophen-Induced Liver Injury Advocates Its Blockage for Therapy of Hepatic Necroinflammation

Frontiers in immunology, 2018-02, Vol.9, p.161

2018

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Type I Interferon Supports Inducible Nitric Oxide Synthase in Murine Hepatoma Cells and Hepatocytes and during Experimental Acetaminophen-Induced Liver Damage

Frontiers in immunology, 2017-07, Vol.8, p.890-890

2017

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Interleukin-36γ is causative for liver damage upon infection with Rift Valley fever virus in type I interferon receptor-deficient mice

Frontiers in immunology, 2023-09, Vol.14, p.1194733-1194733

2023

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Hypothermia Promotes Interleukin-22 Expression and Fine-Tunes Its Biological Activity

Frontiers in immunology, 2017-06, Vol.8, p.742-742

2017

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Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1

PLoS pathogens, 2010-10, Vol.6 (10), p.e1001144-e1001144

2010

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IL-18/IL-18BP and IL-22/IL-22BP: Two interrelated couples with therapeutic potential

Cellular signalling, 2019-11, Vol.63, p.109388-109388, Article 109388

2019

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Interleukin-18 directly activates T-bet expression and function via p38 mitogen-activated protein kinase and nuclear factor-κB in acute myeloid leukemia–derived predendritic KG-1 cells

Molecular cancer therapeutics, 2007-02, Vol.6 (2), p.723-731

2007

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STAT3, a Key Parameter of Cytokine-Driven Tissue Protection during Sterile Inflammation - the Case of Experimental Acetaminophen (Paracetamol)-Induced Liver Damage

Frontiers in immunology, 2016-05, Vol.7, p.163-163

Mühl, Heiko

2016

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IL‐22 in tissue‐protective therapy

British journal of pharmacology, 2013-06, Vol.169 (4), p.761-771

2013

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Pro-Inflammatory Signaling by IL-10 and IL-22: Bad Habit Stirred Up by Interferons?

Frontiers in immunology, 2013-01, Vol.4, p.18-18

Mühl, Heiko

2013

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Epigenetic regulation by CpG methylation splits strong from retarded IFNγ-induced IL-18BP in epithelial versus monocytic cells

Biochimica et biophysica acta. Gene regulatory mechanisms, 2018-03, Vol.1861 (3), p.191-199

2018

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IL-36γ/IL-1F9, an Innate T-bet Target in Myeloid Cells

The Journal of biological chemistry, 2012-12, Vol.287 (50), p.41684-41696

2012

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Inducible NO synthase and antibacterial host defence in times of Th17/Th22/T22 immunity

Cellular microbiology, 2011-03, Vol.13 (3), p.340-348

2011

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Targeting cathepsin C ameliorates murine acetaminophen-induced liver injury

Theranostics, 2024-01, Vol.14 (8), p.3029-3042

2024

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IFNα converts IL-22 into a cytokine efficiently activating STAT1 and its downstream targets

Biochemical pharmacology, 2013-02, Vol.85 (3), p.396-403

2013

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Systemic Anti-TNFα Treatment Restores Diabetes-Impaired Skin Repair in ob/ob Mice by Inactivation of Macrophages

Journal of investigative dermatology, 2007-09, Vol.127 (9), p.2259-2267

2007

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Though Active on RINm5F Insulinoma Cells and Cultured Pancreatic Islets, Recombinant IL-22 Fails to Modulate Cytotoxicity and Disease in a Protocol of Streptozotocin-Induced Experimental Diabetes

Frontiers in pharmacology, 2016-01, Vol.6, p.317

2016

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Pathogenetic mechanisms and therapeutic approaches of acute-to-chronic liver failure

American Journal of Physiology: Cell Physiology, 2023-07, Vol.325 (1), p.C129-C140

2023

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Interferon‐α curbs production of interleukin‐22 by human peripheral blood mononuclear cells exposed to live Borrelia burgdorferi

Journal of cellular and molecular medicine, 2015-10, Vol.19 (10), p.2507-2511

2015

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3'mRNA sequencing reveals pro-regenerative properties of c5ar1 during resolution of murine acetaminophen-induced liver injury

npj Regenerative medicine, 2022-01, Vol.7 (1), p.10-10

2022

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Molecular mechanisms of IL‐18BP regulation in DLD‐1 cells: pivotal direct action of the STAT1/GAS axis on the promoter level

Journal of cellular and molecular medicine, 2009-08, Vol.13 (8b), p.1987-1994

2009

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Molecular signature of interleukin-22 in colon carcinoma cells and organoid models

Translational research : the journal of laboratory and clinical medicine, 2020-02, Vol.216, p.1-22

2020

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Molecular mechanisms of PDGF-AA expression induced by the dsRNA-mimetic poly (I:C) and IL-18

Biochemical and biophysical research communications, 2013-06, Vol.435 (4), p.691-695

2013

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IFN-gamma impairs release of IL-8 by IL-1beta-stimulated A549 lung carcinoma cells

BMC cancer, 2008-09, Vol.8 (1), p.265-265, Article 265

2008

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Interleukin-18 bioactivity: a novel target for immunopharmacological anti-inflammatory intervention

European journal of pharmacology, 2004-10, Vol.500 (1), p.63-71

2004

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A Prominent Role of Interleukin-18 in Acetaminophen-Induced Liver Injury Advocates Its Blockage for Therapy of Hepatic Necroinflammation

Type I Interferon Supports Inducible Nitric Oxide Synthase in Murine Hepatoma Cells and Hepatocytes and during Experimental Acetaminophen-Induced Liver Damage

Interleukin-36γ is causative for liver damage upon infection with Rift Valley fever virus in type I interferon receptor-deficient mice

Hypothermia Promotes Interleukin-22 Expression and Fine-Tunes Its Biological Activity

Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1

IL-18/IL-18BP and IL-22/IL-22BP: Two interrelated couples with therapeutic potential

Interleukin-18 directly activates T-bet expression and function via p38 mitogen-activated protein kinase and nuclear factor-κB in acute myeloid leukemia–derived predendritic KG-1 cells

STAT3, a Key Parameter of Cytokine-Driven Tissue Protection during Sterile Inflammation - the Case of Experimental Acetaminophen (Paracetamol)-Induced Liver Damage

IL‐22 in tissue‐protective therapy

Pro-Inflammatory Signaling by IL-10 and IL-22: Bad Habit Stirred Up by Interferons?

Epigenetic regulation by CpG methylation splits strong from retarded IFNγ-induced IL-18BP in epithelial versus monocytic cells

IL-36γ/IL-1F9, an Innate T-bet Target in Myeloid Cells

Inducible NO synthase and antibacterial host defence in times of Th17/Th22/T22 immunity

Targeting cathepsin C ameliorates murine acetaminophen-induced liver injury

IFNα converts IL-22 into a cytokine efficiently activating STAT1 and its downstream targets

Systemic Anti-TNFα Treatment Restores Diabetes-Impaired Skin Repair in ob/ob Mice by Inactivation of Macrophages

Though Active on RINm5F Insulinoma Cells and Cultured Pancreatic Islets, Recombinant IL-22 Fails to Modulate Cytotoxicity and Disease in a Protocol of Streptozotocin-Induced Experimental Diabetes

Pathogenetic mechanisms and therapeutic approaches of acute-to-chronic liver failure

Interferon‐α curbs production of interleukin‐22 by human peripheral blood mononuclear cells exposed to live Borrelia burgdorferi

3'mRNA sequencing reveals pro-regenerative properties of c5ar1 during resolution of murine acetaminophen-induced liver injury

Molecular mechanisms of IL‐18BP regulation in DLD‐1 cells: pivotal direct action of the STAT1/GAS axis on the promoter level

Molecular signature of interleukin-22 in colon carcinoma cells and organoid models

Molecular mechanisms of PDGF-AA expression induced by the dsRNA-mimetic poly (I:C) and IL-18

IFN-gamma impairs release of IL-8 by IL-1beta-stimulated A549 lung carcinoma cells

Interleukin-18 bioactivity: a novel target for immunopharmacological anti-inflammatory intervention

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