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"Stormy waters ahead": global emergence of carbapenemases

Frontiers in microbiology, 2013, Vol.4, p.48-48

2013

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NDM-5 and OXA-181 Beta-Lactamases, a Significant Threat Continues To Spread in the Americas

Antimicrobial agents and chemotherapy, 2017-07, Vol.61 (7)

2017

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Molecular Diversity and Plasmid Analysis of KPC-Producing Escherichia coli

Antimicrobial agents and chemotherapy, 2016-07, Vol.60 (7), p.4073-4081

2016

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Inhibitor Resistance in the KPC-2 β-Lactamase, a Preeminent Property of This Class A β-Lactamase

Antimicrobial Agents and Chemotherapy, 2010-02, Vol.54 (2), p.890-897

2010

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Nacubactam Enhances Meropenem Activity against Carbapenem-Resistant Klebsiella pneumoniae Producing KPC

Antimicrobial agents and chemotherapy, 2019-08, Vol.63 (8)

2019

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Population Structure, Molecular Epidemiology, and β-Lactamase Diversity among Stenotrophomonas maltophilia Isolates in the United States

mBio, 2019-07, Vol.10 (4)

2019

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In Vitro Activity of Fosfomycin against blaKPC-Containing Klebsiella pneumoniae Isolates, Including Those Nonsusceptible to Tigecycline and/or Colistin

Antimicrobial Agents and Chemotherapy, 2010-01, Vol.54 (1), p.526-529

2010

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OXA-23 β-Lactamase Overexpression in Acinetobacter baumannii Drives Physiological Changes Resulting in New Genetic Vulnerabilities

mBio, 2021-12, Vol.12 (6), p.e0313721-e0313721

2021

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Structures of the Class D Carbapenemases OXA-23 and OXA-146: Mechanistic Basis of Activity against Carbapenems, Extended-Spectrum Cephalosporins, and Aztreonam

Antimicrobial Agents and Chemotherapy, 2013-10, Vol.57 (10), p.4848-4855

2013

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Extended-Spectrum β-Lactamases in Klebsiella pneumoniae Bloodstream Isolates from Seven Countries: Dominance and Widespread Prevalence of SHV- and CTX-M-Type β-Lactamases

Antimicrobial Agents and Chemotherapy, 2003-11, Vol.47 (11), p.3554-3560

2003

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Complete Sequence of a blaKPC-2-Harboring IncFIIK1 Plasmid from a Klebsiella pneumoniae Sequence Type 258 Strain

Antimicrobial Agents and Chemotherapy, 2013-03, Vol.57 (3), p.1542-1545

2013

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Infectious Diseases Society of America Guidance on the Treatment of AmpC β-Lactamase–Producing Enterobacterales, Carbapenem-Resistant Acinetobacter baumannii, and Stenotrophomonas maltophilia Infections

Clinical infectious diseases, 2022-07, Vol.74 (12), p.2089-2114

2022

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Effect of Antibiotic Treatment on Establishment and Elimination of Intestinal Colonization by KPC-Producing Klebsiella pneumoniae in Mice

Antimicrobial Agents and Chemotherapy, 2011-06, Vol.55 (6), p.2585-2589

2011

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Infectious Diseases Society of America 2022 Guidance on the Treatment of Extended-Spectrum β-lactamase Producing Enterobacterales (ESBL-E), Carbapenem-Resistant Enterobacterales (CRE), and Pseudomonas aeruginosa with Difficult-to-Treat Resistance (DTR-P. aeruginosa)

Clinical infectious diseases, 2022-08, Vol.75 (2), p.187-212

2022

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Extended-Spectrum AmpC Cephalosporinase in Acinetobacter baumannii: ADC-56 Confers Resistance to Cefepime

Antimicrobial Agents and Chemotherapy, 2011-10, Vol.55 (10), p.4922-4925

2011

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The role of the plasmid-mediated fluoroquinolone resistance genes as resistance mechanisms in pediatric infections due to Enterobacterales

Frontiers in cellular and infection microbiology, 2023-10, Vol.13, p.1249505-1249505

2023

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Resistance Emergence Mechanism and Mechanism of Resistance Suppression by Tobramycin for Cefepime for Pseudomonas aeruginosa

Antimicrobial Agents and Chemotherapy, 2012-01, Vol.56 (1), p.231-242

2012

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Understanding the Molecular Determinants of Substrate and Inhibitor Specificities in the Carbapenemase KPC-2: Exploring the Roles of Arg220 and Glu276

Antimicrobial Agents and Chemotherapy, 2012-08, Vol.56 (8), p.4428-4438

2012

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Structural Origins of Oxacillinase Specificity in Class D β-Lactamases

Antimicrobial Agents and Chemotherapy, 2014-01, Vol.58 (1), p.333-341

2014

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Crystal Structures of KPC-2 β-Lactamase in Complex with 3-Nitrophenyl Boronic Acid and the Penam Sulfone PSR-3-226

Antimicrobial Agents and Chemotherapy, 2012-05, Vol.56 (5), p.2713-2718

2012

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EDITORIAL COMMENTARY: Ceftazidime-Avibactam and Carbapenem-Resistant Enterobacteriaceae: "We're Gonna Need a Bigger Boat"

Clinical infectious diseases, 2016-12, Vol.63 (12), p.1619-1621

2016

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Can Inhibitor-Resistant Substitutions in the Mycobacterium tuberculosis β-Lactamase BlaC Lead to Clavulanate Resistance?: a Biochemical Rationale for the Use of β-Lactam–β-Lactamase Inhibitor Combinations

Antimicrobial Agents and Chemotherapy, 2013-12, Vol.57 (12), p.6085-6096

2013

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Multiplex Real-Time PCR for Detection of an Epidemic KPC-Producing Klebsiella pneumoniae ST258 Clone

Antimicrobial Agents and Chemotherapy, 2012-06, Vol.56 (6), p.3444-3447

2012

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Substrate Selectivity and a Novel Role in Inhibitor Discrimination by Residue 237 in the KPC-2 β-Lactamase

Antimicrobial Agents and Chemotherapy, 2010-07, Vol.54 (7), p.2867-2877

2010

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"Stormy waters ahead": global emergence of carbapenemases

NDM-5 and OXA-181 Beta-Lactamases, a Significant Threat Continues To Spread in the Americas

Molecular Diversity and Plasmid Analysis of KPC-Producing Escherichia coli

Inhibitor Resistance in the KPC-2 β-Lactamase, a Preeminent Property of This Class A β-Lactamase

Nacubactam Enhances Meropenem Activity against Carbapenem-Resistant Klebsiella pneumoniae Producing KPC

Population Structure, Molecular Epidemiology, and β-Lactamase Diversity among Stenotrophomonas maltophilia Isolates in the United States

In Vitro Activity of Fosfomycin against blaKPC-Containing Klebsiella pneumoniae Isolates, Including Those Nonsusceptible to Tigecycline and/or Colistin

OXA-23 β-Lactamase Overexpression in Acinetobacter baumannii Drives Physiological Changes Resulting in New Genetic Vulnerabilities

Structures of the Class D Carbapenemases OXA-23 and OXA-146: Mechanistic Basis of Activity against Carbapenems, Extended-Spectrum Cephalosporins, and Aztreonam

Extended-Spectrum β-Lactamases in Klebsiella pneumoniae Bloodstream Isolates from Seven Countries: Dominance and Widespread Prevalence of SHV- and CTX-M-Type β-Lactamases

Complete Sequence of a blaKPC-2-Harboring IncFIIK1 Plasmid from a Klebsiella pneumoniae Sequence Type 258 Strain

Infectious Diseases Society of America Guidance on the Treatment of AmpC β-Lactamase–Producing Enterobacterales, Carbapenem-Resistant Acinetobacter baumannii, and Stenotrophomonas maltophilia Infections

Effect of Antibiotic Treatment on Establishment and Elimination of Intestinal Colonization by KPC-Producing Klebsiella pneumoniae in Mice

Infectious Diseases Society of America 2022 Guidance on the Treatment of Extended-Spectrum β-lactamase Producing Enterobacterales (ESBL-E), Carbapenem-Resistant Enterobacterales (CRE), and Pseudomonas aeruginosa with Difficult-to-Treat Resistance (DTR-P. aeruginosa)

Inhibiting Mycobacterium abscessus Cell Wall Synthesis: Using a Novel Diazabicyclooctane β-Lactamase Inhibitor To Augment β-Lactam Action

Extended-Spectrum AmpC Cephalosporinase in Acinetobacter baumannii: ADC-56 Confers Resistance to Cefepime

The role of the plasmid-mediated fluoroquinolone resistance genes as resistance mechanisms in pediatric infections due to Enterobacterales

Resistance Emergence Mechanism and Mechanism of Resistance Suppression by Tobramycin for Cefepime for Pseudomonas aeruginosa

Understanding the Molecular Determinants of Substrate and Inhibitor Specificities in the Carbapenemase KPC-2: Exploring the Roles of Arg220 and Glu276

Structural Origins of Oxacillinase Specificity in Class D β-Lactamases

Crystal Structures of KPC-2 β-Lactamase in Complex with 3-Nitrophenyl Boronic Acid and the Penam Sulfone PSR-3-226

EDITORIAL COMMENTARY: Ceftazidime-Avibactam and Carbapenem-Resistant Enterobacteriaceae: "We're Gonna Need a Bigger Boat"

Can Inhibitor-Resistant Substitutions in the Mycobacterium tuberculosis β-Lactamase BlaC Lead to Clavulanate Resistance?: a Biochemical Rationale for the Use of β-Lactam–β-Lactamase Inhibitor Combinations

Multiplex Real-Time PCR for Detection of an Epidemic KPC-Producing Klebsiella pneumoniae ST258 Clone

Substrate Selectivity and a Novel Role in Inhibitor Discrimination by Residue 237 in the KPC-2 β-Lactamase

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