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Leveraging external data in the design and analysis of clinical trials in neuro-oncology

The lancet oncology, 2021-10, Vol.22 (10), p.e456-e465

2021

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Virus Specific Immune Responses after Human Neoadjuvant Adenovirus-mediated Suicide Gene Therapy for Prostate Cancer

European urology, 2005-07, Vol.48 (1), p.153-161

2005

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Targeting of the rasT24 oncogene to the proximal convoluted tubules in transgenic mice results in hyperplasia and polycystic kidneys

The American journal of pathology, 1993-04, Vol.142 (4), p.1051-1060

1993

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Intravenous administration of replication‐incompetent adenovirus to rhesus monkeys induces thrombocytopenia by increasing in vivo platelet clearance

British journal of haematology, 2003-12, Vol.123 (5), p.903-905

2003

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p53 is required for both radiation-induced differentiation and rescue of V(D)J rearrangement in scid mouse thymocytes

Genes & development, 1996-03, Vol.10 (5), p.553-565

1996

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Phase I study of replication-competent adenovirus-mediated double suicide gene therapy for the treatment of locally recurrent prostate cancer

Cancer research (Chicago, Ill.), 2002-09, Vol.62 (17), p.4968-4976

2002

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Adenovirus-Mediated Thymidine Kinase Gene Therapy in Combination with Topotecan for Patients with Recurrent Ovarian Cancer: 2.5-Year Follow-Up

Gynecologic oncology, 2001-12, Vol.83 (3), p.549-554

2001

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Treatment with human metalloproteinase-8 gene delivery ameliorates experimental rat liver cirrhosis

Gastroenterology (New York, N.Y. 1943), 2004-04, Vol.126 (4), p.1122-1133

2004

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Metastatic and Nonmetastatic Models of Retinoblastoma

The American journal of pathology, 2000-10, Vol.157 (4), p.1405-1412

2000

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Sensitivity and reproducibility in adenoviral infectious titer determination

Nature medicine, 1997-07, Vol.3 (7), p.808-811

1997

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Thymic nurse cells are sites of thymocyte apoptosis

The Journal of immunology (1950), 1994-03, Vol.152 (6), p.2645-2651

1994

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Instability of adenoviral vectors during transport and its implication for clinical studies

Nature medicine, 1999-08, Vol.5 (8), p.955-957

1999

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A clinical trial of retroviral-mediated transfer of a rev-responsive element decoy gene into CD34+ cells from the bone marrow of human immunodeficiency virus-1-infected children

Blood, 1999-07, Vol.94 (1), p.368-371

1999

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Adenoviral-mediated thymidine kinase gene transfer into the primate brain followed by systemic ganciclovir: pathologic, radiologic, and molecular studies

Human gene therapy, 1996-06, Vol.7 (10), p.1241-1250

1996

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TAK, an HIV Tat-Associated Kinase, is a Member of the Cyclin-Dependent Family of Protein Kinases and is Induced by Activation of Peripheral Blood Lymphocytes and Differentiation of Promonocytic Cell Lines

Proceedings of the National Academy of Sciences - PNAS, 1997-11, Vol.94 (23), p.12331-12336

1997

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Vectorology recapitulates virology-will it capitulate oncology?

Nature biotechnology, 2003-07, Vol.21 (7), p.756-757

Aguilar-Cordova, Estaurdo

2003

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Suicide gene therapy for prostate cancer using a replication-deficient adenovirus containing the herpesvirus thymidine kinase gene

World journal of urology, 2000-04, Vol.18 (2), p.125-129

2000

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P2.07-059 Phase I Trial of Gene Mediated Cytotoxic Immunotherapy (GMCI) for Malignant Pleural Effusion (MPE) and Malignant Pleural Mesothelioma (MPM)

Journal of thoracic oncology, 2017-11, Vol.12 (11), p.S2151-S2152

2017

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The combination of adenoviral HSV TK gene therapy and radiation is effective in athymic mouse glioblastoma xenografts without increasing toxic side effects

Journal of neuro-oncology, 2004-03, Vol.67 (1-2), p.177-188

2004

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Efficient ectopic gene expression targeting chick mesoderm

Developmental dynamics, 2002-07, Vol.224 (3), p.291-302

2002

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Lethal toxicity, severe endothelial injury, and a threshold effect with high doses of an adenoviral vector in baboons

Human gene therapy, 2002-01, Vol.13 (1), p.143-154

2002

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Suicide gene therapy for treatment of retinoblastoma in a murine model

Human gene therapy, 1999-02, Vol.10 (3), p.441-448

1999

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Rapid isolation of substrate-quality plasmid DNA without CsCl-dye density gradients

BioTechniques, 1990-11, Vol.9 (5), p.538

1990

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Phase I trial of gene-mediated cytotoxic immunotherapy in combination with chemoradiation for locally advanced pancreatic cancer

Journal of clinical oncology, 2011-02, Vol.29 (4_suppl), p.195-195

2011

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Genotyping of bovine kappa-casein loci following DNA sequence amplification

Bio/technology (New York, N.Y. 1983), 1990-02, Vol.8 (2), p.144-146

1990

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Leveraging external data in the design and analysis of clinical trials in neuro-oncology

Virus Specific Immune Responses after Human Neoadjuvant Adenovirus-mediated Suicide Gene Therapy for Prostate Cancer

Targeting of the rasT24 oncogene to the proximal convoluted tubules in transgenic mice results in hyperplasia and polycystic kidneys

Intravenous administration of replication‐incompetent adenovirus to rhesus monkeys induces thrombocytopenia by increasing in vivo platelet clearance

p53 is required for both radiation-induced differentiation and rescue of V(D)J rearrangement in scid mouse thymocytes

Phase I study of replication-competent adenovirus-mediated double suicide gene therapy for the treatment of locally recurrent prostate cancer

Adenovirus-Mediated Thymidine Kinase Gene Therapy in Combination with Topotecan for Patients with Recurrent Ovarian Cancer: 2.5-Year Follow-Up

Treatment with human metalloproteinase-8 gene delivery ameliorates experimental rat liver cirrhosis

Metastatic and Nonmetastatic Models of Retinoblastoma

Sensitivity and reproducibility in adenoviral infectious titer determination

Thymic nurse cells are sites of thymocyte apoptosis

Instability of adenoviral vectors during transport and its implication for clinical studies

A clinical trial of retroviral-mediated transfer of a rev-responsive element decoy gene into CD34+ cells from the bone marrow of human immunodeficiency virus-1-infected children

Adenoviral-mediated thymidine kinase gene transfer into the primate brain followed by systemic ganciclovir: pathologic, radiologic, and molecular studies

TAK, an HIV Tat-Associated Kinase, is a Member of the Cyclin-Dependent Family of Protein Kinases and is Induced by Activation of Peripheral Blood Lymphocytes and Differentiation of Promonocytic Cell Lines

Vectorology recapitulates virology-will it capitulate oncology?

Suicide gene therapy for prostate cancer using a replication-deficient adenovirus containing the herpesvirus thymidine kinase gene

P2.07-059 Phase I Trial of Gene Mediated Cytotoxic Immunotherapy (GMCI) for Malignant Pleural Effusion (MPE) and Malignant Pleural Mesothelioma (MPM)

The combination of adenoviral HSV TK gene therapy and radiation is effective in athymic mouse glioblastoma xenografts without increasing toxic side effects

Efficient ectopic gene expression targeting chick mesoderm

Lethal toxicity, severe endothelial injury, and a threshold effect with high doses of an adenoviral vector in baboons

Suicide gene therapy for treatment of retinoblastoma in a murine model

Rapid isolation of substrate-quality plasmid DNA without CsCl-dye density gradients

Phase I trial of gene-mediated cytotoxic immunotherapy in combination with chemoradiation for locally advanced pancreatic cancer

Genotyping of bovine kappa-casein loci following DNA sequence amplification

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