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Leveraging external data in the design and analysis of clinical trials in neuro-oncology

The lancet oncology, 2021-10, Vol.22 (10), p.e456-e465

2021

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Histologic and immunohistochemical analysis of tissue response to adenovirus‐mediated herpes simplex thymidine kinase gene therapy of ovarian cancer

International journal of gynecological cancer, 2002-01, Vol.12 (1), p.66-73

2002

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Gene therapy for prostate cancer: toxicological profile of four HSV-tk transducing adenoviral vectors regulated by different promoters

Prostate cancer and prostatic diseases, 2002-12, Vol.5 (4), p.316-325

2002

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Virus Specific Immune Responses after Human Neoadjuvant Adenovirus-mediated Suicide Gene Therapy for Prostate Cancer

European urology, 2005-07, Vol.48 (1), p.153-161

2005

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Targeting of the rasT24 oncogene to the proximal convoluted tubules in transgenic mice results in hyperplasia and polycystic kidneys

The American journal of pathology, 1993-04, Vol.142 (4), p.1051-1060

1993

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Intravenous administration of replication‐incompetent adenovirus to rhesus monkeys induces thrombocytopenia by increasing in vivo platelet clearance

British journal of haematology, 2003-12, Vol.123 (5), p.903-905

2003

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p53 is required for both radiation-induced differentiation and rescue of V(D)J rearrangement in scid mouse thymocytes

Genes & development, 1996-03, Vol.10 (5), p.553-565

1996

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Phase I study of replication-competent adenovirus-mediated double suicide gene therapy for the treatment of locally recurrent prostate cancer

Cancer research (Chicago, Ill.), 2002-09, Vol.62 (17), p.4968-4976

2002

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Adenovirus-Mediated Thymidine Kinase Gene Therapy in Combination with Topotecan for Patients with Recurrent Ovarian Cancer: 2.5-Year Follow-Up

Gynecologic oncology, 2001-12, Vol.83 (3), p.549-554

2001

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Treatment with human metalloproteinase-8 gene delivery ameliorates experimental rat liver cirrhosis

Gastroenterology (New York, N.Y. 1943), 2004-04, Vol.126 (4), p.1122-1133

2004

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Metastatic and Nonmetastatic Models of Retinoblastoma

The American journal of pathology, 2000-10, Vol.157 (4), p.1405-1412

2000

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Administration of Helper-Dependent Adenoviral Vectors and Sequential Delivery of Different Vector Serotype for Long-Term Liver-Directed Gene Transfer in Baboons

Proceedings of the National Academy of Sciences - PNAS, 1999-10, Vol.96 (22), p.12816-12821

1999

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Sensitivity and reproducibility in adenoviral infectious titer determination

Nature medicine, 1997-07, Vol.3 (7), p.808-811

1997

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Thymic nurse cells are sites of thymocyte apoptosis

The Journal of immunology (1950), 1994-03, Vol.152 (6), p.2645

1994

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Instability of adenoviral vectors during transport and its implication for clinical studies

Nature medicine, 1999-08, Vol.5 (8), p.955-957

1999

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A clinical trial of retroviral-mediated transfer of a rev-responsive element decoy gene into CD34+ cells from the bone marrow of human immunodeficiency virus-1-infected children

Blood, 1999-07, Vol.94 (1), p.368-371

1999

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TAK, an HIV Tat-Associated Kinase, is a Member of the Cyclin-Dependent Family of Protein Kinases and is Induced by Activation of Peripheral Blood Lymphocytes and Differentiation of Promonocytic Cell Lines

Proceedings of the National Academy of Sciences - PNAS, 1997-11, Vol.94 (23), p.12331-12336

1997

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Adenoviral gene transfer into dendritic cells efficiently amplifies the immune response to LMP2A antigen: A potential treatment strategy for Epstein‐Barr virus–positive Hodgkin's lymphoma

International journal of cancer, 2001-09, Vol.93 (5), p.706-713

2001

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Suicide gene therapy for prostate cancer using a replication-deficient adenovirus containing the herpesvirus thymidine kinase gene

World journal of urology, 2000-04, Vol.18 (2), p.125-129

2000

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SUICIDE GENE THERAPY TOXICITY AFTER MULTIPLE AND REPEAT INJECTIONS IN PATIENTS WITH LOCALIZED PROSTATE CANCER

The Journal of urology, 2000-06, Vol.163 (6), p.1747-1750

2000

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Phase I–II trial evaluating combined intensity-modulated radiotherapy and in situ gene therapy with or without hormonal therapy in treatment of prostate cancer—interim report on PSA response and biopsy data

International journal of radiation oncology, biology, physics, 2004-04, Vol.58 (5), p.1520-1529

2004

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Thymidine kinase (TK) gene therapy of solid tumors: valacyclovir facilitates outpatient treatment

Anticancer research, 1999-05, Vol.19 (3B), p.2163

1999

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Phase I/II trial evaluating combined radiotherapy and in situ gene therapy with or without hormonal therapy in the treatment of prostate cancer : A preliminary report

International journal of radiation oncology, biology, physics, 2001-11, Vol.51 (3), p.605-613

2001

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Evolution of a gene therapy clinical trial. From bench to bedside and back

Journal of neuro-oncology, 2003-12, Vol.65 (3), p.307

2003

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P2.07-059 Phase I Trial of Gene Mediated Cytotoxic Immunotherapy (GMCI) for Malignant Pleural Effusion (MPE) and Malignant Pleural Mesothelioma (MPM)

Journal of thoracic oncology, 2017-11, Vol.12 (11), p.S2151-S2152

2017

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Leveraging external data in the design and analysis of clinical trials in neuro-oncology

Histologic and immunohistochemical analysis of tissue response to adenovirus‐mediated herpes simplex thymidine kinase gene therapy of ovarian cancer

Gene therapy for prostate cancer: toxicological profile of four HSV-tk transducing adenoviral vectors regulated by different promoters

Virus Specific Immune Responses after Human Neoadjuvant Adenovirus-mediated Suicide Gene Therapy for Prostate Cancer

Targeting of the rasT24 oncogene to the proximal convoluted tubules in transgenic mice results in hyperplasia and polycystic kidneys

Intravenous administration of replication‐incompetent adenovirus to rhesus monkeys induces thrombocytopenia by increasing in vivo platelet clearance

p53 is required for both radiation-induced differentiation and rescue of V(D)J rearrangement in scid mouse thymocytes

Phase I study of replication-competent adenovirus-mediated double suicide gene therapy for the treatment of locally recurrent prostate cancer

Adenovirus-Mediated Thymidine Kinase Gene Therapy in Combination with Topotecan for Patients with Recurrent Ovarian Cancer: 2.5-Year Follow-Up

Treatment with human metalloproteinase-8 gene delivery ameliorates experimental rat liver cirrhosis

Metastatic and Nonmetastatic Models of Retinoblastoma

Administration of Helper-Dependent Adenoviral Vectors and Sequential Delivery of Different Vector Serotype for Long-Term Liver-Directed Gene Transfer in Baboons

Sensitivity and reproducibility in adenoviral infectious titer determination

Thymic nurse cells are sites of thymocyte apoptosis

Instability of adenoviral vectors during transport and its implication for clinical studies

A clinical trial of retroviral-mediated transfer of a rev-responsive element decoy gene into CD34+ cells from the bone marrow of human immunodeficiency virus-1-infected children

TAK, an HIV Tat-Associated Kinase, is a Member of the Cyclin-Dependent Family of Protein Kinases and is Induced by Activation of Peripheral Blood Lymphocytes and Differentiation of Promonocytic Cell Lines

Adenoviral gene transfer into dendritic cells efficiently amplifies the immune response to LMP2A antigen: A potential treatment strategy for Epstein‐Barr virus–positive Hodgkin's lymphoma

Suicide gene therapy for prostate cancer using a replication-deficient adenovirus containing the herpesvirus thymidine kinase gene

SUICIDE GENE THERAPY TOXICITY AFTER MULTIPLE AND REPEAT INJECTIONS IN PATIENTS WITH LOCALIZED PROSTATE CANCER

Phase I–II trial evaluating combined intensity-modulated radiotherapy and in situ gene therapy with or without hormonal therapy in treatment of prostate cancer—interim report on PSA response and biopsy data

Thymidine kinase (TK) gene therapy of solid tumors: valacyclovir facilitates outpatient treatment

Phase I/II trial evaluating combined radiotherapy and in situ gene therapy with or without hormonal therapy in the treatment of prostate cancer : A preliminary report

Evolution of a gene therapy clinical trial. From bench to bedside and back

P2.07-059 Phase I Trial of Gene Mediated Cytotoxic Immunotherapy (GMCI) for Malignant Pleural Effusion (MPE) and Malignant Pleural Mesothelioma (MPM)

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