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ASK1 contributes to fibrosis and dysfunction in models of kidney disease

The Journal of clinical investigation, 2018-10, Vol.128 (10), p.4485-4500

2018

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Dynamic Chromatin Targeting of BRD4 Stimulates Cardiac Fibroblast Activation

Circulation research, 2019-09, Vol.125 (7), p.662-677

2019

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Cortical bone stem cell-derived exosomes' therapeutic effect on myocardial ischemia-reperfusion and cardiac remodeling

American journal of physiology. Heart and circulatory physiology, 2021-12, Vol.321 (6), p.H1014-H1029

2021

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High Throughput Screen Identifies the DNMT1 (DNA Methyltransferase-1) Inhibitor, 5-Azacytidine, as a Potent Inducer of PTEN (Phosphatase and Tensin Homolog): Central Role for PTEN in 5-Azacytidine Protection Against Pathological Vascular Remodeling

Arteriosclerosis, thrombosis, and vascular biology, 2020-08, Vol.40 (8), p.1854-1869

2020

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Cortical bone stem cells modify cardiac inflammation after myocardial infarction by inducing a novel macrophage phenotype

American journal of physiology. Heart and circulatory physiology, 2021-10, Vol.321 (4), p.H684-H701

2021

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Inhibition of Eicosanoid Degradation Mitigates Fibrosis of the Heart

Circulation research, 2023-01, Vol.132 (1), p.10-29

2023

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p38α: A Profibrotic Signaling Nexus

Circulation (New York, N.Y.), 2017-08, Vol.136 (6), p.562-565

2017

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A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase

FEBS letters, 2010-02, Vol.584 (3), p.631-637

2010

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The potential of targeting epigenetic regulators for the treatment of fibrotic cardiac diseases

Future medicinal chemistry, 2016-09, Vol.8 (13), p.1533-1536

2016

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Identification of Potent and Selective Amidobipyridyl Inhibitors of Protein Kinase D

Journal of medicinal chemistry, 2010-08, Vol.53 (15), p.5422-5438

2010

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3,5-Diarylazoles as novel and selective inhibitors of protein kinase D

Bioorganic & medicinal chemistry letters, 2011-03, Vol.21 (5), p.1447-1451

2011

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Suppression of HDAC nuclear export and cardiomyocyte hypertrophy by novel irreversible inhibitors of CRM1

Biochimica et biophysica acta, 2009-05, Vol.1789 (5), p.422-431

2009

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Dynamic Regulation of Copper Uptake and Detoxification Genes in Saccharomyces cerevisiae

Molecular and Cellular Biology, 1998-05, Vol.18 (5), p.2514-2523

1998

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Screening and identification of a novel class of TGF-β type 1 receptor kinase inhibitor

Journal of biomolecular screening, 2011-08, Vol.16 (7), p.724-733

2011

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A trans-Activation Domain in Yeast Heat Shock Transcription Factor Is Essential for Cell Cycle Progression during Stress

Molecular and Cellular Biology, 1999-01, Vol.19 (1), p.402-411

1999

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p38α: a pro-fibrotic signaling nexus

Circulation (New York, N.Y.), 2017-08, Vol.136 (6), p.562-565

2017

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Sphingolipid biosynthesis in pathogenic fungi: Identification and characterization of the 3-ketosphinganine reductase activity of Candida albicans and Aspergillus fumigatus

Biochimica et biophysica acta, 2006, Vol.1761 (1), p.52-63

2006

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The role of the conserved Lys68:Glu265 intersubunit salt bridge in aspartate aminotransferase kinetics: Multiple forced covariant amino acid substitutions in natural variants

Protein science, 2002-05, Vol.11 (5), p.1062-1073

2002

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Functional Analysis of a Homopolymeric (dA-dT) Element That Provides Nucleosomal Access to Yeast and Mammalian Transcription Factors

The Journal of biological chemistry, 1999-08, Vol.274 (34), p.23752-23760

1999

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The human cDNA for a homologue of the plant enzyme 1-aminocyclopropane-1-carboxylate synthase encodes a protein lacking that activity

Gene, 2001-07, Vol.272 (1-2), p.75-84

2001

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The Candida glabrata Amt1 copper‐sensing transcription factor requires Swi/Snf and Gcn5 at a critical step in copper detoxification

Molecular microbiology, 2001-06, Vol.40 (5), p.1165-1174

2001

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ASK1 contributes to fibrosis and dysfunction in models of kidney disease

The Journal of clinical investigation, 2018-10, Vol.128 (10), p.4485-4500

2018

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tRNA-guanine transglycosylase from Escherichia coli: Gross tRNA structural requirements for recognition

Biochemistry (Easton), 1993-05, Vol.32 (19), p.5239-5246

1993

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Abstract 1440: Identification of a novel EGFR sparing brain penetrant ErbB2 inhibitor with activity against oncogenic ErbB2 mutations

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.1440-1440

2023

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Copper-binding motifs in catalysis, transport, detoxification and signaling

Chemistry & Biology, 1997-08, Vol.4 (8), p.549-560

1997

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ASK1 contributes to fibrosis and dysfunction in models of kidney disease

Dynamic Chromatin Targeting of BRD4 Stimulates Cardiac Fibroblast Activation

Cortical bone stem cell-derived exosomes' therapeutic effect on myocardial ischemia-reperfusion and cardiac remodeling

High Throughput Screen Identifies the DNMT1 (DNA Methyltransferase-1) Inhibitor, 5-Azacytidine, as a Potent Inducer of PTEN (Phosphatase and Tensin Homolog): Central Role for PTEN in 5-Azacytidine Protection Against Pathological Vascular Remodeling

Cortical bone stem cells modify cardiac inflammation after myocardial infarction by inducing a novel macrophage phenotype

Inhibition of Eicosanoid Degradation Mitigates Fibrosis of the Heart

p38α: A Profibrotic Signaling Nexus

A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase

The potential of targeting epigenetic regulators for the treatment of fibrotic cardiac diseases

Identification of Potent and Selective Amidobipyridyl Inhibitors of Protein Kinase D

3,5-Diarylazoles as novel and selective inhibitors of protein kinase D

Suppression of HDAC nuclear export and cardiomyocyte hypertrophy by novel irreversible inhibitors of CRM1

Dynamic Regulation of Copper Uptake and Detoxification Genes in Saccharomyces cerevisiae

Screening and identification of a novel class of TGF-β type 1 receptor kinase inhibitor

A trans-Activation Domain in Yeast Heat Shock Transcription Factor Is Essential for Cell Cycle Progression during Stress

p38α: a pro-fibrotic signaling nexus

Sphingolipid biosynthesis in pathogenic fungi: Identification and characterization of the 3-ketosphinganine reductase activity of Candida albicans and Aspergillus fumigatus

The role of the conserved Lys68:Glu265 intersubunit salt bridge in aspartate aminotransferase kinetics: Multiple forced covariant amino acid substitutions in natural variants

Functional Analysis of a Homopolymeric (dA-dT) Element That Provides Nucleosomal Access to Yeast and Mammalian Transcription Factors

The human cDNA for a homologue of the plant enzyme 1-aminocyclopropane-1-carboxylate synthase encodes a protein lacking that activity

The Candida glabrata Amt1 copper‐sensing transcription factor requires Swi/Snf and Gcn5 at a critical step in copper detoxification

ASK1 contributes to fibrosis and dysfunction in models of kidney disease

tRNA-guanine transglycosylase from Escherichia coli: Gross tRNA structural requirements for recognition

Abstract 1440: Identification of a novel EGFR sparing brain penetrant ErbB2 inhibitor with activity against oncogenic ErbB2 mutations

Copper-binding motifs in catalysis, transport, detoxification and signaling

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