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Synaptotoxicity in Alzheimer's Disease Involved a Dysregulation of Actin Cytoskeleton Dynamics through Cofilin 1 Phosphorylation

The Journal of neuroscience, 2018-11, Vol.38 (48), p.10349-10361

2018

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Activity-dependent tau protein translocation to excitatory synapse is disrupted by exposure to amyloid-beta oligomers

The Journal of neuroscience, 2014-04, Vol.34 (17), p.6084-6097

2014

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A peptide inhibitor of Tau-SH3 interactions ameliorates amyloid-β toxicity

Neurobiology of disease, 2020-02, Vol.134, p.104668-104668, Article 104668

2020

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Alzheimer's disease risk gene BIN1 induces Tau-dependent network hyperexcitability

eLife, 2020-07, Vol.9

2020

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Functional upregulation of system xc− by fibroblast growth factor-2

Neuropharmacology, 2012-02, Vol.62 (2), p.901-906

2012

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Glutathione-mediated neuroprotection against methylmercury neurotoxicity in cortical culture is dependent on MRP1

Neurotoxicology (Park Forest South), 2012-06, Vol.33 (3), p.476-481

2012

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Reciprocal disruption of neuronal signaling and Aβ production mediated by extrasynaptic NMDA receptors: a downward spiral

Cell and tissue research, 2014-05, Vol.356 (2), p.279-286

2014

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Effects of chelators on mercury, iron, and lead neurotoxicity in cortical culture

Neurotoxicology (Park Forest South), 2009, Vol.30 (1), p.47-51

2009

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Iron overload accelerates neuronal amyloid-β production and cognitive impairment in transgenic mice model of Alzheimer's disease

Neurobiology of aging, 2014-10, Vol.35 (10), p.2288-2301

2014

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Reciprocal disruption of neuronal signaling and A[beta] production mediated by extrasynaptic NMDA receptors: a downward spiral

Cell and tissue research, 2014-05, Vol.356 (2), p.279

2014

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Rho‐associated protein kinase 1 (ROCK1) is increased in Alzheimer's disease and ROCK1 depletion reduces amyloid‐β levels in brain

Journal of neurochemistry, 2016-08, Vol.138 (4), p.525-531

2016

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Rho-associated protein kinase 1 (ROCK1) is increased in Alzheimer's disease and ROCK1 depletion reduces amyloid-[beta] levels in brain

Journal of neurochemistry, 2016-08, Vol.138 (4), p.525

2016

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The Alzheimer's disease risk factor CD2AP maintains blood-brain barrier integrity

Human molecular genetics, 2015-12, Vol.24 (23), p.6667-6674

2015

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Synergistic toxicity of the environmental neurotoxins methylmercury and β-N-methylamino-L-alanine

Neuroreport, 2012-03, Vol.23 (4), p.216-219

2012

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Tau‐dependent regulation of neuronal activity by the Alzheimer’s disease risk gene BIN1: Molecular and cell biology/tau

Alzheimer's & dementia, 2020-12, Vol.16 (S3)

2020

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Development of small-molecule Tau-SH3 interaction inhibitors that prevent amyloid-β toxicity and network hyperexcitability

Neurotherapeutics, 2024-01, Vol.21 (1), p.e00291-e00291, Article e00291

2024

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P3‐106: THE ALZHEIMER'S DISEASE RISK GENE BIN1 REGULATES NETWORK HYPEREXCITABILITY

Alzheimer's & dementia, 2018-07, Vol.14 (7S_Part_20), p.P1108-P1108

2018

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THE ALZHEIMER’S DISEASE RISK GENE BIN1 REGULATES NETWORK HYPEREXCITABILITY

Alzheimer's & dementia, 2018-07, Vol.14 (7), p.P1108-P1108

2018

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Rho‐associated protein kinase 1 ( ROCK 1) is increased in Alzheimer's disease and ROCK 1 depletion reduces amyloid‐β levels in brain

Journal of neurochemistry, 2016-08, Vol.138 (4), p.525-531

2016

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Development of small‐molecule tau‐SH3 interaction inhibitors that prevent amyloid‐β toxicity

Alzheimer's & dementia, 2021-12, Vol.17 (S9), p.n/a

2021

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P4‐080: Pharmacologic Inhibition of Rock1 and Rock2 Reverses Dendritic Spine Morphology Abnormalities Associated with Age‐Related Memory Loss and Alzheimer’s Disease

Alzheimer's & dementia, 2016-07, Vol.12 (7S_Part_21), p.P1043-P1044

2016

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The amyloid-β oligomer Aβ56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregation

Science signaling, 2017-05, Vol.10 (478)

2017

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Effects of Token Reinforcement on Physical Activity and Intrinsic Motivation

Research quarterly for exercise and sport, 2014-03, Vol.85 (S1), p.A22

2014

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Specific alterations of tau phosphorylation and neuronal signaling induced by the amyloid-β oligomer Aβ56

Neurobiology of aging, 2016-03, Vol.39, p.S27-S27

2016

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PHARMACOLOGIC INHIBITION OF ROCK1 AND ROCK2 REVERSES DENDRITIC SPINE MORPHOLOGY ABNORMALITIES ASSOCIATED WITH AGE-RELATED MEMORY LOSS AND ALZHEIMER’S DISEASE

Alzheimer's & dementia, 2016-07, Vol.12 (7), p.P1043-P1044

2016

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Synaptotoxicity in Alzheimer's Disease Involved a Dysregulation of Actin Cytoskeleton Dynamics through Cofilin 1 Phosphorylation

Activity-dependent tau protein translocation to excitatory synapse is disrupted by exposure to amyloid-beta oligomers

A peptide inhibitor of Tau-SH3 interactions ameliorates amyloid-β toxicity

Alzheimer's disease risk gene BIN1 induces Tau-dependent network hyperexcitability

Functional upregulation of system xc− by fibroblast growth factor-2

Glutathione-mediated neuroprotection against methylmercury neurotoxicity in cortical culture is dependent on MRP1

Reciprocal disruption of neuronal signaling and Aβ production mediated by extrasynaptic NMDA receptors: a downward spiral

Effects of chelators on mercury, iron, and lead neurotoxicity in cortical culture

Iron overload accelerates neuronal amyloid-β production and cognitive impairment in transgenic mice model of Alzheimer's disease

Reciprocal disruption of neuronal signaling and A[beta] production mediated by extrasynaptic NMDA receptors: a downward spiral

Rho‐associated protein kinase 1 (ROCK1) is increased in Alzheimer's disease and ROCK1 depletion reduces amyloid‐β levels in brain

Rho-associated protein kinase 1 (ROCK1) is increased in Alzheimer's disease and ROCK1 depletion reduces amyloid-[beta] levels in brain

The Alzheimer's disease risk factor CD2AP maintains blood-brain barrier integrity

Synergistic toxicity of the environmental neurotoxins methylmercury and β-N-methylamino-L-alanine

Tau‐dependent regulation of neuronal activity by the Alzheimer’s disease risk gene BIN1: Molecular and cell biology/tau

Development of small-molecule Tau-SH3 interaction inhibitors that prevent amyloid-β toxicity and network hyperexcitability

P3‐106: THE ALZHEIMER'S DISEASE RISK GENE BIN1 REGULATES NETWORK HYPEREXCITABILITY

THE ALZHEIMER’S DISEASE RISK GENE BIN1 REGULATES NETWORK HYPEREXCITABILITY

Rho‐associated protein kinase 1 ( ROCK 1) is increased in Alzheimer's disease and ROCK 1 depletion reduces amyloid‐β levels in brain

Development of small‐molecule tau‐SH3 interaction inhibitors that prevent amyloid‐β toxicity

P4‐080: Pharmacologic Inhibition of Rock1 and Rock2 Reverses Dendritic Spine Morphology Abnormalities Associated with Age‐Related Memory Loss and Alzheimer’s Disease

The amyloid-β oligomer Aβ56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregation

Effects of Token Reinforcement on Physical Activity and Intrinsic Motivation

Specific alterations of tau phosphorylation and neuronal signaling induced by the amyloid-β oligomer Aβ56

PHARMACOLOGIC INHIBITION OF ROCK1 AND ROCK2 REVERSES DENDRITIC SPINE MORPHOLOGY ABNORMALITIES ASSOCIATED WITH AGE-RELATED MEMORY LOSS AND ALZHEIMER’S DISEASE

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