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2365 Nanoliposomal irinotecan (MM-398, nal-IRI) population pharmacokinetics (PK) and its association with efficacy and safety in patients with solid tumors based on the phase 3 study NAPOLI-1 and five phase 1 and 2 studies

European journal of cancer (1990), 2015-09, Vol.51, p.S458-S458

2015

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261 Lesion characterization with ferumoxytol MRI in patients with advanced solid tumors and correlation with treatment response to MM-398, nanoliposomal irinotecan (nal-IRI)

European journal of cancer (1990), 2014-11, Vol.50, p.87-87

2014

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A phase I study of the safety and pharmacokinetics of trabectedin in combination with pegylated liposomal doxorubicin in patients with advanced malignancies

Annals of oncology, 2008-10, Vol.19 (10), p.1802-1809

2008

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Single-agent trabectedin as second-line therapy of persistent or recurrent endometrial cancer: Results of a multicenter phase II study

Gynecologic oncology, 2009-08, Vol.114 (2), p.288-292

2009

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692P First-in-human study of ELU001, a targeted nanoparticle drug conjugate, in subjects with folate receptor α (FRα) overexpressing solid tumors

Annals of oncology, 2023-10, Vol.34, p.S482-S483

2023

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Phase I trial of an antisense oligonucleotide OL(1)p53 in hematologic malignancies

Journal of clinical oncology, 1996-04, Vol.14 (4), p.1320-1326

1996

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Chromosomal transformation in donor cells following allogeneic bone marrow transplantation

Bone marrow transplantation (Basingstoke), 2004-06, Vol.33 (12), p.1253-1256

2004

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A phase 1 study of GBR 1302 in subjects with HER2-positive cancers

Annals of oncology, 2016-11, Vol.27, p.viii16-viii16

2016

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Vasculopathy of small muscular arteries in pediatric patients after bone marrow transplantation

Human pathology, 1999-07, Vol.30 (7), p.734-740

1999

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NAPOLI-1: Randomized Phase 3 Study of MM-398 (NAL-IRI), with or Without 5-Fluorouracil and Leucovorin, Versus 5-Fluorouracil and Leucovorin, in Metastatic Pancreatic Cancer Progressed on or Following Gemcitabine-Based Therapy

Annals of oncology, 2014-06, Vol.25, p.ii105-ii105

2014

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Xenotransplantation: a bold step forward

Annals of allergy, asthma, & immunology, 1995-12, Vol.75 (6 Pt 1), p.461-462

Bayever, E

1995

Volltextzugriff (PDF)

PCN29 - A Systematic Literature Review To Identify And Compare Clinical Trials Evaluating Novel Therapeutic Agents In Post-Gemcitabine Advanced Pancreatic Cancer

Value in health, 2015-11, Vol.18 (7), p.A434-A434

2015

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Final results of NAPOLI-1: A phase 3 study of nal-IRI (MM-398) ± 5-fluorouracil and leucovorin (5-FU/LV) vs 5-FU/LV in metastatic pancreatic cancer (mPAC) previously treated with gemcitabine-based therapy

Annals of oncology, 2016-10, Vol.27, p.vi211-vi211

2016

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A Systematic Literature Review To Identify And Compare Clinical Trials Evaluating Novel Therapeutic Agents In Post-Gemcitabine Advanced Pancreatic Cancer

Value in health, 2015-11, Vol.18 (7), p.A434-A434

2015

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The status of hematopoietic stem cell transplantation in lysosomal storage disease

Pediatric neurology, 2003-11, Vol.29 (5), p.391-403

2003

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8028 Safety analysis of trabectedin in combination with pegylated liposomal doxorubicin (PLD) vs PLD alone in ovarian cancer patients 65 years of age and older

European journal of cancer supplements, 2009, Vol.7 (2), p.458-458

2009

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9427 Efficacy of second-line trabectedin in patients with advanced liposarcomas and leiomyosarcomas progressing despite prior conventional chemotherapy

European journal of cancer supplements, 2009, Vol.7 (2), p.598-598

2009

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GENE TRANSFER INTO HEMATOPOIETIC CELLS

Blood, 1990-04, Vol.75 (7), p.1587-1587

Bayever, Eliel

1990

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Trabectedin (Tr) as single agent for advanced soft tissue sarcomas (STS) failing standard of care: Interim analysis of 1,400 patients (pts) in an expanded access program study

Journal of clinical oncology, 2010-05, Vol.28 (15_suppl), p.10027-10027

2010

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Tolerability of long-term use of trabectedin (Tr) in combination with pegylated liposomal doxorubicin (PLD) in patients (pts) with relapsed ovarian cancer (ROC)

Journal of clinical oncology, 2010-05, Vol.28 (15_suppl), p.5121-5121

2010

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Correlation of CA-125 and RECIST evaluation in recurrent ovarian cancer (ROC): Results from a randomized phase III study of trabectedin (T) with pegylated liposomal doxorubicin (PLD) versus PLD alone

Journal of clinical oncology, 2009-05, Vol.27 (15_suppl), p.5550-5550

2009

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Outcomes of patients (pts) with advanced soft-tissue sarcomas (STS) treated in clinical trials (CTs) versus expanded access programs (EAPs): A decade of experience with single-agent trabectedin (Tr)

Journal of clinical oncology, 2010-05, Vol.28 (15_suppl), p.10029-10029

2010

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Trabectedin (Tr) in the treatment of advanced uterine leiomyosarcomas (U-LMS): Results of a pooled analysis of five single-agent phase II studies using the recommended dose

Journal of clinical oncology, 2010-05, Vol.28 (15_suppl), p.10028-10028

2010

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Allogeneic bone marrow transplantation for children with acute leukemia : long-term follow-up of patients prepared with high-dose cytosine arabinoside and fractionated total body irradiation

Bone marrow transplantation (Basingstoke), 1997-07, Vol.20 (1), p.5-10

1997

Volltextzugriff (PDF)

Long-term results of a randomized phase II study of trabectedin by two different dose and schedule regimens in patients with advanced liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide

Journal of clinical oncology, 2009-05, Vol.27 (15_suppl), p.10509-10509

2009

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2365 Nanoliposomal irinotecan (MM-398, nal-IRI) population pharmacokinetics (PK) and its association with efficacy and safety in patients with solid tumors based on the phase 3 study NAPOLI-1 and five phase 1 and 2 studies

261 Lesion characterization with ferumoxytol MRI in patients with advanced solid tumors and correlation with treatment response to MM-398, nanoliposomal irinotecan (nal-IRI)

A phase I study of the safety and pharmacokinetics of trabectedin in combination with pegylated liposomal doxorubicin in patients with advanced malignancies

Single-agent trabectedin as second-line therapy of persistent or recurrent endometrial cancer: Results of a multicenter phase II study

692P First-in-human study of ELU001, a targeted nanoparticle drug conjugate, in subjects with folate receptor α (FRα) overexpressing solid tumors

Phase I trial of an antisense oligonucleotide OL(1)p53 in hematologic malignancies

Chromosomal transformation in donor cells following allogeneic bone marrow transplantation

A phase 1 study of GBR 1302 in subjects with HER2-positive cancers

Vasculopathy of small muscular arteries in pediatric patients after bone marrow transplantation

NAPOLI-1: Randomized Phase 3 Study of MM-398 (NAL-IRI), with or Without 5-Fluorouracil and Leucovorin, Versus 5-Fluorouracil and Leucovorin, in Metastatic Pancreatic Cancer Progressed on or Following Gemcitabine-Based Therapy

Xenotransplantation: a bold step forward

PCN29 - A Systematic Literature Review To Identify And Compare Clinical Trials Evaluating Novel Therapeutic Agents In Post-Gemcitabine Advanced Pancreatic Cancer

Final results of NAPOLI-1: A phase 3 study of nal-IRI (MM-398) ± 5-fluorouracil and leucovorin (5-FU/LV) vs 5-FU/LV in metastatic pancreatic cancer (mPAC) previously treated with gemcitabine-based therapy

A Systematic Literature Review To Identify And Compare Clinical Trials Evaluating Novel Therapeutic Agents In Post-Gemcitabine Advanced Pancreatic Cancer

The status of hematopoietic stem cell transplantation in lysosomal storage disease

8028 Safety analysis of trabectedin in combination with pegylated liposomal doxorubicin (PLD) vs PLD alone in ovarian cancer patients 65 years of age and older

9427 Efficacy of second-line trabectedin in patients with advanced liposarcomas and leiomyosarcomas progressing despite prior conventional chemotherapy

GENE TRANSFER INTO HEMATOPOIETIC CELLS

Trabectedin (Tr) as single agent for advanced soft tissue sarcomas (STS) failing standard of care: Interim analysis of 1,400 patients (pts) in an expanded access program study

Tolerability of long-term use of trabectedin (Tr) in combination with pegylated liposomal doxorubicin (PLD) in patients (pts) with relapsed ovarian cancer (ROC)

Correlation of CA-125 and RECIST evaluation in recurrent ovarian cancer (ROC): Results from a randomized phase III study of trabectedin (T) with pegylated liposomal doxorubicin (PLD) versus PLD alone

Outcomes of patients (pts) with advanced soft-tissue sarcomas (STS) treated in clinical trials (CTs) versus expanded access programs (EAPs): A decade of experience with single-agent trabectedin (Tr)

Trabectedin (Tr) in the treatment of advanced uterine leiomyosarcomas (U-LMS): Results of a pooled analysis of five single-agent phase II studies using the recommended dose

Allogeneic bone marrow transplantation for children with acute leukemia : long-term follow-up of patients prepared with high-dose cytosine arabinoside and fractionated total body irradiation

Long-term results of a randomized phase II study of trabectedin by two different dose and schedule regimens in patients with advanced liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide

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