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In Vitro Epsilon RNA-Dependent Protein Priming Activity of Human Hepatitis B Virus Polymerase

Journal of Virology, 2012-05, Vol.86 (9), p.5134-5150

2012

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Stephen S. Hecht Has Played a Major Role in Investigating Tobacco Carcinogenesis

Chemical research in toxicology, 2023-04, Vol.36 (4), p.563-564

Spratt, Thomas E.

2023

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Activity of DNA polymerase κ across the genome in human fibroblasts

Proceedings of the National Academy of Sciences - PNAS, 2024-07, Vol.121 (28), p.e2403130121

2024

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Glucuronidation of tobacco-specific nitrosamines by UGT2B10

Drug metabolism and disposition, 2008-05, Vol.36 (5), p.824-830

2008

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DNA Polymerases η and ζ Combine to Bypass O 2‑[4-(3-Pyridyl)-4-oxobutyl]thymine, a DNA Adduct Formed from Tobacco Carcinogens

Chemical research in toxicology, 2016-03, Vol.29 (3), p.303-316

2016

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N 2 -Substituted 2'-Deoxyguanosine Triphosphate Derivatives as Selective Substrates for Human DNA Polymerase κ

Angewandte Chemie International Edition, 2017-03, Vol.56 (10), p.2628-2631

2017

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Functional characterization of low-prevalence missense polymorphisms in the UDP-glucuronosyltransferase 1A9 gene

Drug metabolism and disposition, 2009-10, Vol.37 (10), p.1999-2007

2009

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Identification of Hydrogen Bonds between Escherichia coli DNA Polymerase I (Klenow fragment) and the Minor Groove of DNA by Amino Acid Substitution of the Polymerase and Atomic Substitution of the DNA

Biochemistry (Easton), 2001-03, Vol.40 (9), p.2647-2652

Spratt, Thomas E

2001

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DNA Polymerases η and ζ Combine to Bypass O(2)-[4-(3-Pyridyl)-4-oxobutyl]thymine, a DNA Adduct Formed from Tobacco Carcinogens

Chemical research in toxicology, 2016-03, Vol.29 (3), p.303

2016

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DNA Polymerase ν Rapidly Bypasses O 6‑Methyl-dG but Not O 6‑[4-(3-Pyridyl)-4-oxobutyl-dG and O 2‑Alkyl-dTs

Chemical research in toxicology, 2016-11, Vol.29 (11), p.1894-1900

2016

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Evidence for a Watson-Crick Hydrogen Bonding Requirement in DNA Synthesis by Human DNA Polymerase κ

Molecular and Cellular Biology, 2005-08, Vol.25 (16), p.7137-7143

2005

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Honokiol Inhibits DNA Polymerases β and λ and Increases Bleomycin Sensitivity of Human Cancer Cells

Chemical research in toxicology, 2017-02, Vol.30 (2), p.715-725

2017

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DNA Polymerase ν Rapidly Bypasses O6-Methyl-dG but Not O6-[4-(3-Pyridyl)-4-oxobutyl-dG and O2-Alkyl-dTs

Chemical research in toxicology, 2016-11, Vol.29 (11), p.1894-1900

2016

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Active Site Interactions Impact Phosphoryl Transfer during Replication of Damaged and Undamaged DNA by Escherichia coli DNA Polymerase I

Chemical research in toxicology, 2017-11, Vol.30 (11), p.2033-2043

2017

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N2‐Substituted 2′‐Deoxyguanosine Triphosphate Derivatives as Selective Substrates for Human DNA Polymerase κ

Angewandte Chemie International Edition, 2017-03, Vol.56 (10), p.2628-2631

2017

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Mutagenic Replication of N 2‑Deoxyguanosine Benzo[a]pyrene Adducts by Escherichia coli DNA Polymerase I and Sulfolobus solfataricus DNA Polymerase IV

Chemical research in toxicology, 2017-05, Vol.30 (5), p.1168-1176

2017

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Mutagenic Replication of N2-Deoxyguanosine Benzo[a]pyrene Adducts by Escherichia coli DNA Polymerase I and Sulfolobus solfataricus DNA Polymerase IV

Chemical research in toxicology, 2017-05, Vol.30 (5), p.1168-1176

2017

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Roles of translesion synthesis DNA polymerases in the potent mutagenicity of tobacco-specific nitrosamine-derived O 2-alkylthymidines in human cells

DNA repair, 2015-11, Vol.35, p.63-70

2015

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Fidelity of Mispair Formation and Mispair Extension Is Dependent on the Interaction between the Minor Groove of the Primer Terminus and Arg668 of DNA Polymerase I of Escherichia coli

Biochemistry (Easton), 2005-04, Vol.44 (15), p.5647-5659

2005

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Tobacco-Specific Nitrosamine-Derived O 2-Alkylthymidines Are Potent Mutagenic Lesions in SOS-Induced Escherichia coli

Chemical research in toxicology, 2011-11, Vol.24 (11), p.1833-1835

2011

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Human DNA Polymerase ν Catalyzes Correct and Incorrect DNA Synthesis with High Catalytic Efficiency

The Journal of biological chemistry, 2015-06, Vol.290 (26), p.16292-16303

2015

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Low Fidelity Bypass of O 2-(3-Pyridyl)-4-oxobutylthymine, the Most Persistent Bulky Adduct Produced by the Tobacco Specific Nitrosamine 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone by Model DNA Polymerases

Chemical research in toxicology, 2012-06, Vol.25 (6), p.1195-1202

2012

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An unprecedented nucleic acid capture mechanism for excision of DNA damage

Nature (London), 2010-11, Vol.468 (7322), p.406-411

2010

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Yeast DNA Polymerase η Makes Functional Contacts with the DNA Minor Groove Only at the Incoming Nucleoside Triphosphate

Proceedings of the National Academy of Sciences - PNAS, 2003-04, Vol.100 (9), p.5113-5118

2003

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Low fidelity bypass of O(2)-(3-pyridyl)-4-oxobutylthymine, the most persistent bulky adduct produced by the tobacco specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by model DNA polymerases

Chemical research in toxicology, 2012-06, Vol.25 (6), p.1195

2012

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In Vitro Epsilon RNA-Dependent Protein Priming Activity of Human Hepatitis B Virus Polymerase

Stephen S. Hecht Has Played a Major Role in Investigating Tobacco Carcinogenesis

Activity of DNA polymerase κ across the genome in human fibroblasts

Glucuronidation of tobacco-specific nitrosamines by UGT2B10

DNA Polymerases η and ζ Combine to Bypass O 2‑[4-(3-Pyridyl)-4-oxobutyl]thymine, a DNA Adduct Formed from Tobacco Carcinogens

N 2 -Substituted 2'-Deoxyguanosine Triphosphate Derivatives as Selective Substrates for Human DNA Polymerase κ

Functional characterization of low-prevalence missense polymorphisms in the UDP-glucuronosyltransferase 1A9 gene

Identification of Hydrogen Bonds between Escherichia coli DNA Polymerase I (Klenow fragment) and the Minor Groove of DNA by Amino Acid Substitution of the Polymerase and Atomic Substitution of the DNA

DNA Polymerases η and ζ Combine to Bypass O(2)-[4-(3-Pyridyl)-4-oxobutyl]thymine, a DNA Adduct Formed from Tobacco Carcinogens

DNA Polymerase ν Rapidly Bypasses O 6‑Methyl-dG but Not O 6‑[4-(3-Pyridyl)-4-oxobutyl-dG and O 2‑Alkyl-dTs

Evidence for a Watson-Crick Hydrogen Bonding Requirement in DNA Synthesis by Human DNA Polymerase κ

Honokiol Inhibits DNA Polymerases β and λ and Increases Bleomycin Sensitivity of Human Cancer Cells

DNA Polymerase ν Rapidly Bypasses O6-Methyl-dG but Not O6-[4-(3-Pyridyl)-4-oxobutyl-dG and O2-Alkyl-dTs

Active Site Interactions Impact Phosphoryl Transfer during Replication of Damaged and Undamaged DNA by Escherichia coli DNA Polymerase I

N2‐Substituted 2′‐Deoxyguanosine Triphosphate Derivatives as Selective Substrates for Human DNA Polymerase κ

Mutagenic Replication of N 2‑Deoxyguanosine Benzo[a]pyrene Adducts by Escherichia coli DNA Polymerase I and Sulfolobus solfataricus DNA Polymerase IV

Mutagenic Replication of N2-Deoxyguanosine Benzo[a]pyrene Adducts by Escherichia coli DNA Polymerase I and Sulfolobus solfataricus DNA Polymerase IV

Roles of translesion synthesis DNA polymerases in the potent mutagenicity of tobacco-specific nitrosamine-derived O 2-alkylthymidines in human cells

Fidelity of Mispair Formation and Mispair Extension Is Dependent on the Interaction between the Minor Groove of the Primer Terminus and Arg668 of DNA Polymerase I of Escherichia coli

Tobacco-Specific Nitrosamine-Derived O 2-Alkylthymidines Are Potent Mutagenic Lesions in SOS-Induced Escherichia coli

Human DNA Polymerase ν Catalyzes Correct and Incorrect DNA Synthesis with High Catalytic Efficiency

Low Fidelity Bypass of O 2-(3-Pyridyl)-4-oxobutylthymine, the Most Persistent Bulky Adduct Produced by the Tobacco Specific Nitrosamine 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone by Model DNA Polymerases

An unprecedented nucleic acid capture mechanism for excision of DNA damage

Yeast DNA Polymerase η Makes Functional Contacts with the DNA Minor Groove Only at the Incoming Nucleoside Triphosphate

Low fidelity bypass of O(2)-(3-pyridyl)-4-oxobutylthymine, the most persistent bulky adduct produced by the tobacco specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by model DNA polymerases

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