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Analysis of Non-linear Pharmacokinetics of P-Glycoprotein Substrates in a Microfluidic Device Using a Mathematical Model that Includes an Unstirred Water Layer (UWL) Compartment

Pharmaceutical research, 2021-06, Vol.38 (6), p.1031-1039

2021

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Parallel artificial membrane permeability assay (PAMPA) - Is it better than Caco-2 for human passive permeability prediction?

Mini reviews in medicinal chemistry, 2010-10, Vol.10 (11), p.1071

2010

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Unstirred Water Layers and the Kinetics of Organic Cation Transport

Pharmaceutical research, 2015-09, Vol.32 (9), p.2937-2949

2015

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Estimation of effective intestinal membrane permeability considering bile micelle solubilisation

International journal of pharmaceutics, 2009-02, Vol.368 (1-2), p.116-122

Sugano, Kiyohiko

2009

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Towards a better mechanistic comprehension of drug permeation and absorption: Introducing the diffusion-partitioning interplay

International journal of pharmaceutics, 2021-10, Vol.608, p.121116-121116, Article 121116

2021

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Effect of the unstirred water layer on permeability enhancement by hydrophilic cyclodextrins

International journal of pharmaceutics, 2007-09, Vol.342 (1), p.250-253

2007

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Lipid Absorption Triggers Drug Supersaturation at the Intestinal Unstirred Water Layer and Promotes Drug Absorption from Mixed Micelles

Pharmaceutical research, 2013-12, Vol.30 (12), p.3045-3058

2013

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Possible reduction of effective thickness of intestinal unstirred water layer by particle drifting effect

International journal of pharmaceutics, 2010-03, Vol.387 (1), p.103-109

Sugano, Kiyohiko

2010

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Combined effects of the drug distribution and mucus diffusion properties of self-microemulsifying drug delivery systems on the oral absorption of fenofibrate

International journal of pharmaceutics, 2018-07, Vol.546 (1-2), p.263-271

2018

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Effect of surface charge, particle size, and modification by polyethylene glycol of liposomes on their association with Caco-2 cells across an unstirred water layer

Pharmazie, 2018-01, Vol.73 (1), p.3-8

2018

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Prediction of food effect by bile micelles on oral drug absorption considering free fraction in intestinal fluid

European journal of pharmaceutical sciences, 2010-05, Vol.40 (2), p.118-124

2010

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Drug permeation through biomembranes: cyclodextrins and the unstirred water layer

Pharmazie, 2012-05, Vol.67 (5), p.363-370

Loftsson, T

2012

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Prediction of oral drug absorption in humans by theoretical passive absorption model

International journal of pharmaceutics, 2005-04, Vol.293 (1), p.183-192

2005

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PAMPA—a drug absorption in vitro model: 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones

European journal of pharmaceutical sciences, 2004-03, Vol.21 (4), p.429-441

2004

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Theoretical investigation of passive intestinal membrane permeability using Monte Carlo method to generate drug-like molecule population

International journal of pharmaceutics, 2009-05, Vol.373 (1), p.55-61

Sugano, Kiyohiko

2009

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Physicochemical properties of water and its effect on drug delivery A commentary

International journal of pharmaceutics, 2008-04, Vol.354 (1-2), p.248-254

2008

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In vitro digestion models to evaluate lipid based drug delivery systems; present status and current trends

Advanced drug delivery reviews, 2019-03, Vol.142, p.35-49

2019

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In vitro-in vivo correlation in the effect of cyclodextrin on oral absorption of poorly soluble drugs

International journal of pharmaceutics, 2021-05, Vol.600, p.120494-120494, Article 120494

2021

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Dose-Dependent Solubility-Permeability Interplay for Poorly Soluble Drugs under Non-Sink Conditions

Pharmaceutics, 2021-03, Vol.13 (3), p.323

2021

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Consideration of albumin-mediated hepatic uptake for highly protein-bound anionic drugs: Bridging the gap of hepatic uptake clearance between in vitro and in vivo

Pharmacology & therapeutics (Oxford), 2022-01, Vol.229, p.107938-107938, Article 107938

2022

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Evaluation of the artificial membrane permeability of drugs by digital simulation

European journal of pharmaceutical sciences, 2016-08, Vol.91, p.154-161

2016

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Nasal powders of quercetin-β-cyclodextrin derivatives complexes with mannitol/lecithin microparticles for Nose-to-Brain delivery: In vitro and ex vivo evaluation

International journal of pharmaceutics, 2021-09, Vol.607, p.121016-121016, Article 121016

2021

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Towards a unified model of passive drug permeation I: Origins of the unstirred water layer with applications to ionic permeation

European journal of pharmaceutical sciences, 2014-02, Vol.52, p.109-124

2014

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In vitro dissolution testing of respirable size anti-tubercular drug particles using a small volume dissolution apparatus

International journal of pharmaceutics, 2019-03, Vol.559, p.235-244

2019

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Experimental estimation of the effective unstirred water layer thickness in the human jejunum, and its importance in oral drug absorption

European journal of pharmaceutical sciences, 1995-10, Vol.3 (5), p.247-253

1995

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Analysis of Non-linear Pharmacokinetics of P-Glycoprotein Substrates in a Microfluidic Device Using a Mathematical Model that Includes an Unstirred Water Layer (UWL) Compartment

Parallel artificial membrane permeability assay (PAMPA) - Is it better than Caco-2 for human passive permeability prediction?

Unstirred Water Layers and the Kinetics of Organic Cation Transport

Estimation of effective intestinal membrane permeability considering bile micelle solubilisation

Towards a better mechanistic comprehension of drug permeation and absorption: Introducing the diffusion-partitioning interplay

Effect of the unstirred water layer on permeability enhancement by hydrophilic cyclodextrins

Lipid Absorption Triggers Drug Supersaturation at the Intestinal Unstirred Water Layer and Promotes Drug Absorption from Mixed Micelles

Possible reduction of effective thickness of intestinal unstirred water layer by particle drifting effect

Combined effects of the drug distribution and mucus diffusion properties of self-microemulsifying drug delivery systems on the oral absorption of fenofibrate

Effect of surface charge, particle size, and modification by polyethylene glycol of liposomes on their association with Caco-2 cells across an unstirred water layer

Prediction of food effect by bile micelles on oral drug absorption considering free fraction in intestinal fluid

Drug permeation through biomembranes: cyclodextrins and the unstirred water layer

Prediction of oral drug absorption in humans by theoretical passive absorption model

PAMPA—a drug absorption in vitro model: 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones

Theoretical investigation of passive intestinal membrane permeability using Monte Carlo method to generate drug-like molecule population

Physicochemical properties of water and its effect on drug delivery A commentary

In vitro digestion models to evaluate lipid based drug delivery systems; present status and current trends

In vitro-in vivo correlation in the effect of cyclodextrin on oral absorption of poorly soluble drugs

Dose-Dependent Solubility-Permeability Interplay for Poorly Soluble Drugs under Non-Sink Conditions

Consideration of albumin-mediated hepatic uptake for highly protein-bound anionic drugs: Bridging the gap of hepatic uptake clearance between in vitro and in vivo

Evaluation of the artificial membrane permeability of drugs by digital simulation

Nasal powders of quercetin-β-cyclodextrin derivatives complexes with mannitol/lecithin microparticles for Nose-to-Brain delivery: In vitro and ex vivo evaluation

Towards a unified model of passive drug permeation I: Origins of the unstirred water layer with applications to ionic permeation

In vitro dissolution testing of respirable size anti-tubercular drug particles using a small volume dissolution apparatus

Experimental estimation of the effective unstirred water layer thickness in the human jejunum, and its importance in oral drug absorption

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