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A bone paradigm challenging the standard model of myeloma oncogenesis

Critical reviews in oncology/hematology, 2022-04, Vol.172, p.103640-103640, Article 103640

2022

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Multiple Myeloma as a Bone Disease? The Tissue Disruption-Induced Cell Stochasticity (TiDiS) Theory

Cancers, 2020-08, Vol.12 (8), p.2158

2020

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Noxa up-regulation and mcl-1 cleavage are associated to apoptosis induction by bortezomib in multiple myeloma

Cancer research (Chicago, Ill.), 2007-06, Vol.67 (11), p.5418-5424

2007

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Prediction of Survival in Multiple Myeloma Based on Gene Expression Profiles Reveals Cell Cycle and Chromosomal Instability Signatures in High-Risk Patients and Hyperdiploid Signatures in Low-Risk Patients: A Study of the Intergroupe Francophone du Myélome

Journal of clinical oncology, 2008-10, Vol.26 (29), p.4798-4805

2008

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ABT-737 is highly effective against molecular subgroups of multiple myeloma

Blood, 2011-10, Vol.118 (14), p.3901-3910

2011

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A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines

Haematologica (Roma), 2011-04, Vol.96 (4), p.574-582

2011

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Toll-like receptors: lessons to learn from normal and malignant human B cells

Blood, 2008-09, Vol.112 (6), p.2205-2213

2008

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Myeloma cells induce imbalance in the osteoprotegerin/osteoprotegerin ligand system in the human bone marrow environment

Blood, 2001-12, Vol.98 (13), p.3527-3533

2001

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TLR3 Ligand Induces NF-κB Activation and Various Fates of Multiple Myeloma Cells Depending on IFN-α Production

The Journal of immunology (1950), 2009-04, Vol.182 (7), p.4471-4478

2009

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Recurrent 14q32 translocations determine the prognosis of multiple myeloma, especially in patients receiving intensive chemotherapy

Blood, 2002-09, Vol.100 (5), p.1579-1583

2002

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Rearrangements of the c-myc oncogene are present in 15% of primary human multiple myeloma tumors

Blood, 2001-11, Vol.98 (10), p.3082-3086

2001

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Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-xL is an essential survival protein of human myeloma cells

Blood, 2002-07, Vol.100 (1), p.194-199

2002

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Interleukin-6 is a growth factor for nonmalignant human plasmablasts

Blood, 2001-03, Vol.97 (6), p.1817-1822

2001

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CD20 is associated with a small mature plasma cell morphology and t(11;14) in multiple myeloma

Blood, 2003-08, Vol.102 (3), p.1070-1071

2003

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Chromosome 13 abnormalities identified by FISH analysis and serum β2-microglobulin produce a powerful myeloma staging system for patients receiving high-dose therapy

Blood, 2001-03, Vol.97 (6), p.1566-1571

2001

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Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentation

Blood, 2002-03, Vol.99 (6), p.2185-2191

2002

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A Prospective, Randomized Trial of Autologous Bone Marrow Transplantation and Chemotherapy in Multiple Myeloma

The New England journal of medicine, 1996-07, Vol.335 (2), p.91-97

1996

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The Ins and Outs of Endosteal Niche Disruption in the Bone Marrow: Relevance for Myeloma Oncogenesis

Biology (Basel, Switzerland), 2023-07, Vol.12 (7), p.990

2023

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The peripheral CD138+ population but not the CD138− population contains myeloma clonogenic cells in plasma cell leukaemia patients

British journal of haematology, 2012-03, Vol.156 (5), p.679-683

2012

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Phenotypic characterization of the human myeloma cell growth fraction

Blood, 2005-06, Vol.105 (12), p.4845-4848

2005

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Multiple Myeloma Exemplifies a Model of Cancer Based on Tissue Disruption as the Initiator Event

Frontiers in oncology, 2018-09, Vol.8, p.355-355

2018

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Multiple Myeloma

The New England journal of medicine, 1997-06, Vol.336 (23), p.1657-1664

1997

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Impact of XIAP protein levels on the survival of myeloma cells

Haematologica (Roma), 2009-01, Vol.94 (1), p.87-93

2009

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Translocation t(11;14)(q13;q32) is the hallmark of IgM, IgE, and nonsecretory multiple myeloma variants

Blood, 2003-02, Vol.101 (4), p.1570-1571

2003

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A bone paradigm challenging the standard model of myeloma oncogenesis

Multiple Myeloma as a Bone Disease? The Tissue Disruption-Induced Cell Stochasticity (TiDiS) Theory

Noxa up-regulation and mcl-1 cleavage are associated to apoptosis induction by bortezomib in multiple myeloma

Prediction of Survival in Multiple Myeloma Based on Gene Expression Profiles Reveals Cell Cycle and Chromosomal Instability Signatures in High-Risk Patients and Hyperdiploid Signatures in Low-Risk Patients: A Study of the Intergroupe Francophone du Myélome

ABT-737 is highly effective against molecular subgroups of multiple myeloma

A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines

Toll-like receptors: lessons to learn from normal and malignant human B cells

Myeloma cells induce imbalance in the osteoprotegerin/osteoprotegerin ligand system in the human bone marrow environment

TLR3 Ligand Induces NF-κB Activation and Various Fates of Multiple Myeloma Cells Depending on IFN-α Production

Genetic abnormalities and survival in multiple myeloma: the experience of the Intergroupe Francophone du Myélome

Recurrent 14q32 translocations determine the prognosis of multiple myeloma, especially in patients receiving intensive chemotherapy

Rearrangements of the c-myc oncogene are present in 15% of primary human multiple myeloma tumors

Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-xL is an essential survival protein of human myeloma cells

Interleukin-6 is a growth factor for nonmalignant human plasmablasts

CD20 is associated with a small mature plasma cell morphology and t(11;14) in multiple myeloma

Chromosome 13 abnormalities identified by FISH analysis and serum β2-microglobulin produce a powerful myeloma staging system for patients receiving high-dose therapy

Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentation

A Prospective, Randomized Trial of Autologous Bone Marrow Transplantation and Chemotherapy in Multiple Myeloma

The Ins and Outs of Endosteal Niche Disruption in the Bone Marrow: Relevance for Myeloma Oncogenesis

The peripheral CD138+ population but not the CD138− population contains myeloma clonogenic cells in plasma cell leukaemia patients

Phenotypic characterization of the human myeloma cell growth fraction

Multiple Myeloma Exemplifies a Model of Cancer Based on Tissue Disruption as the Initiator Event

Multiple Myeloma

Impact of XIAP protein levels on the survival of myeloma cells

Translocation t(11;14)(q13;q32) is the hallmark of IgM, IgE, and nonsecretory multiple myeloma variants

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