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Adverse outcome pathway networks I: Development and applications

Environmental toxicology and chemistry, 2018-06, Vol.37 (6), p.1723-1733

2018

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Human exposure pathways to poly- and perfluoroalkyl substances (PFAS) from indoor media: A systematic review protocol

Environment international, 2021-01, Vol.146, p.106308-106308, Article 106308

2021

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Tipping the Balance: Hepatotoxicity and the 4 Apical Key Events of Hepatic Steatosis

Toxicological sciences, 2016-04, Vol.150 (2), p.261-268

2016

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Adverse outcome pathways: a concise introduction for toxicologists

Archives of toxicology, 2017-11, Vol.91 (11), p.3697-3707

2017

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Integrating Publicly Available Data to Generate Computationally Predicted Adverse Outcome Pathways for Fatty Liver

Toxicological sciences, 2016-04, Vol.150 (2), p.510-520

2016

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Adverse outcome pathway networks II: Network analytics

Environmental toxicology and chemistry, 2018-06, Vol.37 (6), p.1734-1748

2018

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Comparative analysis of temporal and dose-dependent TCDD-elicited gene expression in human, mouse, and rat primary hepatocytes

Toxicological sciences, 2013-05, Vol.133 (1), p.54-66

2013

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Standardization of the collection of exhaled breath condensate and exhaled breath aerosol using a feedback regulated sampling device

Journal of breath research, 2017-11, Vol.11 (4), p.047107-047107

2017

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Leveraging human genetic and adverse outcome pathway (AOP) data to inform susceptibility in human health risk assessment

Mammalian genome, 2018-02, Vol.29 (1-2), p.190-204

2018

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Probe Molecule (PrM) Approach in Adverse Outcome Pathway (AOP) Based High-Throughput Screening (HTS): In Vivo Discovery for Developing in Vitro Target Methods

Chemical research in toxicology, 2015-04, Vol.28 (4), p.551-559

2015

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Advancing systematic-review methodology in exposure science for environmental health decision making

Journal of exposure science & environmental epidemiology, 2020-11, Vol.30 (6), p.906-916

2020

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Dietary fat is a lipid source in 2,3,7,8-tetrachlorodibenzo-ρ-dioxin (TCDD)-elicited hepatic steatosis in C57BL/6 mice

Toxicological sciences, 2012-08, Vol.128 (2), p.377-386

2012

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Use of systematic evidence maps within the US Environmental Protection Agency (EPA) Integrated Risk Information System (IRIS) program: Advancements to date and looking ahead

Environment international, 2022-11, Vol.169, p.107363-107363, Article 107363

2022

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Aryl Hydrocarbon Receptor-Mediated Induction of Stearoyl-CoA Desaturase 1 Alters Hepatic Fatty Acid Composition in TCDD-Elicited Steatosis

Toxicological sciences, 2011-12, Vol.124 (2), p.299-310

2011

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TCDD-elicited effects on liver, serum, and adipose lipid composition in C57BL/6 mice

Toxicological sciences, 2013-01, Vol.131 (1), p.108-115

2013

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Taxonomic applicability of inflammatory cytokines in adverse outcome pathway (AOP) development

Journal of Toxicology and Environmental Health, Part A, 2016-02, Vol.79 (4), p.184-196

2016

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Immunochemistry for high-throughput screening of human exhaled breath condensate (EBC) media: implementation of automated quanterix SIMOA instrumentation

Journal of breath research, 2015-12, Vol.9 (4), p.047108-047108

2015

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Utility of In Vitro Bioactivity as a Lower Bound Estimate of In Vivo Adverse Effect Levels and in Risk-Based Prioritization

Toxicological sciences, 2020-01, Vol.173 (1), p.202-225

2020

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Progress in data interoperability to support computational toxicology and chemical safety evaluation

Toxicology and applied pharmacology, 2019-10, Vol.380, p.114707-114707, Article 114707

2019

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Predicting the Probability that a Chemical Causes Steatosis Using Adverse Outcome Pathway Bayesian Networks (AOPBNs)

Risk analysis, 2020-03, Vol.40 (3), p.512-523

2020

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Endogenous and Synthetic ABHD5 Ligands Regulate ABHD5-Perilipin Interactions and Lipolysis in Fat and Muscle

Cell metabolism, 2015-11, Vol.22 (5), p.851-860

2015

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Why adverse outcome pathways need to be FAIR

ALTEX, 2024-01, Vol.41 (1), p.50-56

2024

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Diets enriched with coconut, fish, or olive oil modify peripheral metabolic effects of ozone in rats

Toxicology and applied pharmacology, 2021-01, Vol.410, p.115337-115337, Article 115337

2021

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Systematic evidence map (SEM) template: Report format and methods used for the US EPA Integrated Risk Information System (IRIS) program, Provisional Peer Reviewed Toxicity Value (PPRTV) program, and other “fit for purpose” literature-based human health analyses

Environment international, 2022-11, Vol.169, p.107468, Article 107468

2022

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Corrigendum to “Systematic evidence map (SEM) template: Report format and methods used for the US EPA Integrated Risk Information System (IRIS) program, Provisional Peer Reviewed Toxicity Value (PPRTV) program, and other “fit for purpose” literature-based human health analyses” [Environ. Int. 169 (2022) 107468]

Environment international, 2023-06, Vol.176, p.107929-107929, Article 107929

2023

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Adverse outcome pathway networks I: Development and applications

Human exposure pathways to poly- and perfluoroalkyl substances (PFAS) from indoor media: A systematic review protocol

Tipping the Balance: Hepatotoxicity and the 4 Apical Key Events of Hepatic Steatosis

Adverse outcome pathways: a concise introduction for toxicologists

Integrating Publicly Available Data to Generate Computationally Predicted Adverse Outcome Pathways for Fatty Liver

Adverse outcome pathway networks II: Network analytics

Comparative analysis of temporal and dose-dependent TCDD-elicited gene expression in human, mouse, and rat primary hepatocytes

Standardization of the collection of exhaled breath condensate and exhaled breath aerosol using a feedback regulated sampling device

Leveraging human genetic and adverse outcome pathway (AOP) data to inform susceptibility in human health risk assessment

Probe Molecule (PrM) Approach in Adverse Outcome Pathway (AOP) Based High-Throughput Screening (HTS): In Vivo Discovery for Developing in Vitro Target Methods

Advancing systematic-review methodology in exposure science for environmental health decision making

Dietary fat is a lipid source in 2,3,7,8-tetrachlorodibenzo-ρ-dioxin (TCDD)-elicited hepatic steatosis in C57BL/6 mice

Use of systematic evidence maps within the US Environmental Protection Agency (EPA) Integrated Risk Information System (IRIS) program: Advancements to date and looking ahead

Aryl Hydrocarbon Receptor-Mediated Induction of Stearoyl-CoA Desaturase 1 Alters Hepatic Fatty Acid Composition in TCDD-Elicited Steatosis

TCDD-elicited effects on liver, serum, and adipose lipid composition in C57BL/6 mice

Taxonomic applicability of inflammatory cytokines in adverse outcome pathway (AOP) development

Immunochemistry for high-throughput screening of human exhaled breath condensate (EBC) media: implementation of automated quanterix SIMOA instrumentation

Utility of In Vitro Bioactivity as a Lower Bound Estimate of In Vivo Adverse Effect Levels and in Risk-Based Prioritization

Progress in data interoperability to support computational toxicology and chemical safety evaluation

Predicting the Probability that a Chemical Causes Steatosis Using Adverse Outcome Pathway Bayesian Networks (AOPBNs)

Endogenous and Synthetic ABHD5 Ligands Regulate ABHD5-Perilipin Interactions and Lipolysis in Fat and Muscle

Why adverse outcome pathways need to be FAIR

Diets enriched with coconut, fish, or olive oil modify peripheral metabolic effects of ozone in rats

Systematic evidence map (SEM) template: Report format and methods used for the US EPA Integrated Risk Information System (IRIS) program, Provisional Peer Reviewed Toxicity Value (PPRTV) program, and other “fit for purpose” literature-based human health analyses

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