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Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

Cell, 2010-03, Vol.140 (6), p.900-917

Hotamisligil, Gökhan S.

2010

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Endoplasmic Reticulum Stress and Inflammation in Obesity and Diabetes

Circulation research, 2010-09, Vol.107 (5), p.579-591

2010

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Chronic enrichment of hepatic endoplasmic reticulum-mitochondria contact leads to mitochondrial dysfunction in obesity

Nature medicine, 2014-12, Vol.20 (12), p.1427-1435

2014

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Inflammation and metabolic disorders

Nature, 2006-12, Vol.444 (7121), p.860-867

Hotamisligil, G.S

2006

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Linking the inflammasome to obesity-related disease

Nature medicine, 2011-02, Vol.17 (2), p.164-165

2011

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Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice

Nature medicine, 2009-08, Vol.15 (8), p.940-945

2009

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Foundations of Immunometabolism and Implications for Metabolic Health and Disease

Immunity (Cambridge, Mass.), 2017-09, Vol.47 (3), p.406-420

Hotamisligil, Gökhan S.

2017

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Serum fatty acid-binding protein 4 is a predictor of cardiovascular events in end-stage renal disease

PloS one, 2011-11, Vol.6 (11), p.e27356-e27356

2011

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Turning off the inflammatory, but not the metabolic, flames

Nature medicine, 2013-03, Vol.19 (3), p.265-267

2013

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A central role for JNK in obesity and insulin resistance

Nature (London), 2002-11, Vol.420 (6913), p.333-336

2002

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Polysome profiling in liver identifies dynamic regulation of endoplasmic reticulum translatome by obesity and fasting

PLoS genetics, 2012-08, Vol.8 (8), p.e1002902-e1002902

2012

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A predominant role for parenchymal c-Jun amino terminal kinase (JNK) in the regulation of systemic insulin sensitivity

PloS one, 2008-09, Vol.3 (9), p.e3151-e3151

2008

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Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity

Nature medicine, 2018-03, Vol.24 (3), p.292-303

2018

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The unfolded protein response regulates hepatic autophagy by sXBP1-mediated activation of TFEB

Autophagy, 2021-08, Vol.17 (8), p.1841-1855

2021

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Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression

Cell metabolism, 2024-07, Vol.36 (7), p.1550-1565.e9

2024

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ER Stress Promotes Inflammation through Re-wIREd Macrophages in Obesity

Molecular cell, 2017-06, Vol.66 (6), p.731-733

2017

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Leptin Deficiency Shifts Mast Cells toward Anti-Inflammatory Actions and Protects Mice from Obesity and Diabetes by Polarizing M2 Macrophages

Cell metabolism, 2015-12, Vol.22 (6), p.1045-1058

2015

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Uncoupling of Metabolic Health from Longevity through Genetic Alteration of Adipose Tissue Lipid-Binding Proteins

Cell reports (Cambridge), 2017-10, Vol.21 (2), p.393-402

2017

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The transcription factor GATA2 regulates differentiation of brown adipocytes

EMBO reports, 2005-09, Vol.6 (9), p.879-884

2005

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Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function

Nature (London), 1997-10, Vol.389 (6651), p.610-614

1997

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Neuronal PTP1B regulates body weight, adiposity and leptin action

Nature medicine, 2006-08, Vol.12 (8), p.917-924

2006

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Molecular mechanisms of adipocyte differentiation

Reviews in endocrine & metabolic disorders, 2001-10, Vol.2 (4), p.349-355

2001

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Organic cation transporter 3 (Oct3) is a distinct catecholamines clearance route in adipocytes mediating the beiging of white adipose tissue

PLoS biology, 2019-01, Vol.17 (1), p.e2006571-e2006571

2019

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p38α blocks brown adipose tissue thermogenesis through p38δ inhibition

PLoS biology, 2018-07, Vol.16 (7), p.e2004455-e2004455

2018

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Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

Endoplasmic Reticulum Stress and Inflammation in Obesity and Diabetes

Chronic enrichment of hepatic endoplasmic reticulum-mitochondria contact leads to mitochondrial dysfunction in obesity

Inflammation and metabolic disorders

Linking the inflammasome to obesity-related disease

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice

Foundations of Immunometabolism and Implications for Metabolic Health and Disease

Serum fatty acid-binding protein 4 is a predictor of cardiovascular events in end-stage renal disease

Turning off the inflammatory, but not the metabolic, flames

A central role for JNK in obesity and insulin resistance

Polysome profiling in liver identifies dynamic regulation of endoplasmic reticulum translatome by obesity and fasting

A predominant role for parenchymal c-Jun amino terminal kinase (JNK) in the regulation of systemic insulin sensitivity

Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity

The unfolded protein response regulates hepatic autophagy by sXBP1-mediated activation of TFEB

Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression

12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat

ER Stress Promotes Inflammation through Re-wIREd Macrophages in Obesity

Leptin Deficiency Shifts Mast Cells toward Anti-Inflammatory Actions and Protects Mice from Obesity and Diabetes by Polarizing M2 Macrophages

Uncoupling of Metabolic Health from Longevity through Genetic Alteration of Adipose Tissue Lipid-Binding Proteins

The transcription factor GATA2 regulates differentiation of brown adipocytes

Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function

Neuronal PTP1B regulates body weight, adiposity and leptin action

Molecular mechanisms of adipocyte differentiation

Organic cation transporter 3 (Oct3) is a distinct catecholamines clearance route in adipocytes mediating the beiging of white adipose tissue

p38α blocks brown adipose tissue thermogenesis through p38δ inhibition

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