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Induction of Apoptosis in Hepatocellular Carcinoma Cell Lines by Novel Indolylacrylamide Derivatives: Synthesis and Biological Evaluation

Chemistry & biodiversity, 2021-05, Vol.18 (5), p.e2001037-n/a

2021

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A new triazolothiadiazine derivative inhibits stemness and induces cell death in HCC by oxidative stress dependent JNK pathway activation

Scientific reports, 2022-09, Vol.12 (1), p.15139-15139, Article 15139

2022

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Human Hepatocellular Carcinoma Classification from H&E Stained Histopathology Images with 3D Convolutional Neural Networks and Focal Loss Function

Journal of imaging, 2023-01, Vol.9 (2), p.25

2023

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Object‐Oriented Segmentation of Cell Nuclei in Fluorescence Microscopy Images

Cytometry. Part A, 2018-10, Vol.93 (10), p.1019-1028

2018

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Synthesis of novel indole-isoxazole hybrids and evaluation of their cytotoxic activities on hepatocellular carcinoma cell lines

BMC chemistry, 2021-12, Vol.15 (1), p.66-66, Article 66

2021

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Recent applications of deep learning and machine intelligence on in silico drug discovery: methods, tools and databases

Briefings in bioinformatics, 2019-09, Vol.20 (5), p.1878-1912

2019

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A visual object tracking benchmark for cell motility in time-lapse imaging

Signal, image and video processing, 2019-09, Vol.13 (6), p.1063-1070

2019

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A Series of 2,4(1H,3H)-Quinazolinedione Derivatives: Synthesis and Biological Evaluation as Potential Anticancer Agents

Letters in drug design & discovery, 2016-01, Vol.13 (1), p.64-76

2016

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Context dependent isoform specific PI3K inhibition confers drug resistance in hepatocellular carcinoma cells

BMC cancer, 2022-03, Vol.22 (1), p.320-17, Article 320

2022

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Intermittent Hypoxia Attenuates and Reverses Epinephrine‐Induced Changes in Gene Expression in Endothelial Cells

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Synthesis, anticancer activity, toxicity evaluation and molecular docking studies of novel phenylaminopyrimidine—(thio)urea hybrids as potential kinase inhibitors

Computational biology and chemistry, 2019-02, Vol.78, p.227-241

2019

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Development of a novel zebrafish xenograft model in ache mutants using liver cancer cell lines

Scientific reports, 2018-01, Vol.8 (1), p.1570-14, Article 1570

2018

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Design, Synthesis and In Vitro Cytotoxic Activity of New 6,9-Disubstituted Purine Analogues

Acta chimica Slovenica, 2020-03, Vol.67 (1), p.70-82

2020

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Contrast Enhancement of Microscopy Images Using Image Phase Information

IEEE access, 2018-01, Vol.6, p.3839-3850

2018

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Intermittent Hypoxia-Induced Activation of Endothelial Cells Is Mediated via Sympathetic Activation-Dependent Catecholamine Release

Frontiers in physiology, 2021-07, Vol.12, p.701995-701995

2021

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Design, synthesis, and biological evaluation of indole-based 1,4-disubstituted piperazines as cytotoxic agents

Turkish journal of chemistry, 2012-01

2012

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Synthesis and Cytotoxicity Studies on Novel Piperazinylacetamides

Letters in drug design & discovery, 2019-01, Vol.16 (1), p.45-51

2019

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Cytotoxicity of Hydrazones of Morpholine Bearing Mannich Bases Towards Huh7 and T47D Cell Lines and Their Effects on Mitochondrial Respiration

Letters in drug design & discovery, 2016-10, Vol.13 (8), p.734-741

2016

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DEEPScreen: high performance drug-target interaction prediction with convolutional neural networks using 2-D structural compound representations

Chemical science (Cambridge), 2020-03, Vol.11 (9), p.2531-2557

2020

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Drug Repurposing Approach to Identify Candidate Drug Molecules for Hepatocellular Carcinoma

International journal of molecular sciences, 2024-08, Vol.25 (17), p.9392

2024

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Novel indole-pyrazole hybrids as potential tubulin-targeting agents; Synthesis, antiproliferative evaluation, and molecular modeling studies

Journal of molecular structure, 2023-08, Vol.1285, p.135477, Article 135477

2023

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Abstract LB-A08: Differential alteration of IL-8 in response to Sorafenib and PI3K/Akt/mTOR inhibitors in liver cancer cells and in liver cancer stem cells

Molecular cancer therapeutics, 2018-01, Vol.17 (1_Supplement), p.LB-A08-LB-A08

2018

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Design and synthesis of novel substituted indole-acrylamide derivatives and evaluation of their anti-cancer activity as potential tubulin-targeting agents

Journal of molecular structure, 2022-04, Vol.1254, p.132345, Article 132345

2022

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Synthesis and biological evaluation of novel isoxazole-piperazine hybrids as potential anti-cancer agents with inhibitory effect on liver cancer stem cells

European journal of medicinal chemistry, 2021-10, Vol.221, p.113489-113489, Article 113489

2021

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Bioactivity-guided isolation of cytotoxic secondary metabolites from the roots of Glycyrrhiza glabra and elucidation of their mechanisms of action

Industrial crops and products, 2018-11, Vol.124, p.389-396

2018

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Induction of Apoptosis in Hepatocellular Carcinoma Cell Lines by Novel Indolylacrylamide Derivatives: Synthesis and Biological Evaluation

A new triazolothiadiazine derivative inhibits stemness and induces cell death in HCC by oxidative stress dependent JNK pathway activation

Human Hepatocellular Carcinoma Classification from H&E Stained Histopathology Images with 3D Convolutional Neural Networks and Focal Loss Function

Object‐Oriented Segmentation of Cell Nuclei in Fluorescence Microscopy Images

Synthesis of novel indole-isoxazole hybrids and evaluation of their cytotoxic activities on hepatocellular carcinoma cell lines

Recent applications of deep learning and machine intelligence on in silico drug discovery: methods, tools and databases

A visual object tracking benchmark for cell motility in time-lapse imaging

A Series of 2,4(1H,3H)-Quinazolinedione Derivatives: Synthesis and Biological Evaluation as Potential Anticancer Agents

Context dependent isoform specific PI3K inhibition confers drug resistance in hepatocellular carcinoma cells

Intermittent Hypoxia Attenuates and Reverses Epinephrine‐Induced Changes in Gene Expression in Endothelial Cells

Synthesis, anticancer activity, toxicity evaluation and molecular docking studies of novel phenylaminopyrimidine—(thio)urea hybrids as potential kinase inhibitors

Development of a novel zebrafish xenograft model in ache mutants using liver cancer cell lines

Design, Synthesis and In Vitro Cytotoxic Activity of New 6,9-Disubstituted Purine Analogues

Contrast Enhancement of Microscopy Images Using Image Phase Information

Intermittent Hypoxia-Induced Activation of Endothelial Cells Is Mediated via Sympathetic Activation-Dependent Catecholamine Release

Design, synthesis, and biological evaluation of indole-based 1,4-disubstituted piperazines as cytotoxic agents

Synthesis and Cytotoxicity Studies on Novel Piperazinylacetamides

Cytotoxicity of Hydrazones of Morpholine Bearing Mannich Bases Towards Huh7 and T47D Cell Lines and Their Effects on Mitochondrial Respiration

DEEPScreen: high performance drug-target interaction prediction with convolutional neural networks using 2-D structural compound representations

Drug Repurposing Approach to Identify Candidate Drug Molecules for Hepatocellular Carcinoma

Novel indole-pyrazole hybrids as potential tubulin-targeting agents; Synthesis, antiproliferative evaluation, and molecular modeling studies

Abstract LB-A08: Differential alteration of IL-8 in response to Sorafenib and PI3K/Akt/mTOR inhibitors in liver cancer cells and in liver cancer stem cells

Design and synthesis of novel substituted indole-acrylamide derivatives and evaluation of their anti-cancer activity as potential tubulin-targeting agents

Synthesis and biological evaluation of novel isoxazole-piperazine hybrids as potential anti-cancer agents with inhibitory effect on liver cancer stem cells

Bioactivity-guided isolation of cytotoxic secondary metabolites from the roots of Glycyrrhiza glabra and elucidation of their mechanisms of action

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