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Dorothy Hodgkin Lecture 2014 Understanding genes identified by genome-wide association studies for Type 2 diabetes

Diabetic medicine, 2014-12, Vol.31 (12), p.1480-1487

Rutter, G. A.

2014

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Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion

Diabetologia, 2010-08, Vol.53 (8), p.1656-1668

2010

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Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion

Diabetologia, 2014-01, Vol.57 (1), p.122-128

2014

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Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice

Diabetologia, 2012-10, Vol.55 (10), p.2667-2676

2012

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Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y requires changes in AMP-activated protein kinase activity

Diabetologia, 2007-01, Vol.50 (1), p.168-177

2007

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Glutamine potently stimulates glucagon-like peptide-1 secretion from GLUTag cells

Diabetologia, 2004-09, Vol.47 (9), p.1592-1601

2004

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Visualising insulin secretion. The Minkowski Lecture 2004

Diabetologia, 2004-11, Vol.47 (11), p.1861-1872

RUTTER, G. A

2004

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Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion

Diabetologia, 2011-04, Vol.54 (4), p.819-827

2011

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AMP-activated protein kinase regulates glucagon secretion from mouse pancreatic alpha cells

Diabetologia, 2011-01, Vol.54 (1), p.125-134

2011

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Over-expression of AMP-activated protein kinase impairs pancreatic β-cell function in vivo

Journal of endocrinology, 2005-11, Vol.187 (2), p.225-235

2005

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Variance stabilization and normalization for one-color microarray data using a data-driven multiscale approach

Bioinformatics, 2006-10, Vol.22 (20), p.2547-2553

2006

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Intracellular ATP-sensitive K+ channels in mouse pancreatic beta cells : against a role in organelle cation homeostasis

Diabetologia, 2006-07, Vol.49 (7), p.1567-1577

2006

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Physical Exercise–Induced Hypoglycemia Caused by Failed Silencing of Monocarboxylate Transporter 1 in Pancreatic β Cells

American journal of human genetics, 2007-09, Vol.81 (3), p.467-474

2007

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Stimulated Ca2+ influx raises mitochondrial free Ca2+ to supramicromolar levels in a pancreatic beta-cell line. Possible role in glucose and agonist-induced insulin secretion

The Journal of biological chemistry, 1993-10, Vol.268 (30), p.22385-22390

1993

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Mitochondrial calcium transporting pathways during hypoxia and reoxygenation in single rat cardiomyocytes

Cardiovascular research, 1998-08, Vol.39 (2), p.423-433

1998

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Kiss and run exocytosis of dense core secretory vesicles

Neuroreport, 2004-01, Vol.15 (1), p.79-81

2004

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Ca2+ stores in insulin-secreting cells : lack of effect of cADP ribose

Cell calcium (Edinburgh), 1994-08, Vol.16 (2), p.71-80

1994

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Low lactate dehydrogenase and high mitochondrial glycerol phosphate dehydrogenase in pancreatic beta cells: potential role in nutrient sensing

The Journal of biological chemistry, 1994-02, Vol.269 (7), p.4895-4902

1994

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Regulation of pyruvate dehydrogenase by insulin and polyamines within electropermeabilized fat-cells and isolated mitochondria

Biochemical journal, 1992-07, Vol.285 (2), p.435-439

1992

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Effects of insulin and guanosine 5'-[γ-thio]triphosphate on fatty acid synthesis and lipolysis within electropermeabilized fat-cells

Biochemical journal, 1992-01, Vol.281 (2), p.431-435

1992

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Ca2+-Induced Ca2+ Release in Pancreatic Islet β-Cells: Critical Evaluation of the Use of Endoplasmic Reticulum-Targeted “Cameleons”

Endocrinology (Philadelphia), 2004-10, Vol.145 (10), p.4540-4549

2004

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Ablation of AMP-activated protein kinase α1 and α2 from mouse pancreatic beta cells and RIP2. Cre neurons suppresses insulin release in vivo

Diabetologia, 2010, Vol.53 (5), p.924-936

2010

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Regulation of the pyruvate dehydrogenase complex by Ca2+ within toluene-permeabilized heart mitochondria

Biochimica et biophysica acta, 1989-12, Vol.1014 (3), p.263

1989

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Effects of protein phosphatase inhibitors on the regulation of insulin-sensitive enzymes within rat epidimal fat-pads and cells

Biochemical journal, 1991, Vol.276, p.649-654

1991

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Regulation of mitochondrial glycerol-phosphate dehydrogenase by Ca2+ within electropermeabilized insulin-secreting cells (INS-1)

Biochimica et biophysica acta. Molecular cell research, 1992-12, Vol.1175 (1), p.107-113

1992

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Dorothy Hodgkin Lecture 2014 Understanding genes identified by genome-wide association studies for Type 2 diabetes

Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion

Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion

Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice

Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y requires changes in AMP-activated protein kinase activity

Glutamine potently stimulates glucagon-like peptide-1 secretion from GLUTag cells

Visualising insulin secretion. The Minkowski Lecture 2004

Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion

AMP-activated protein kinase regulates glucagon secretion from mouse pancreatic alpha cells

Over-expression of AMP-activated protein kinase impairs pancreatic β-cell function in vivo

Variance stabilization and normalization for one-color microarray data using a data-driven multiscale approach

Intracellular ATP-sensitive K+ channels in mouse pancreatic beta cells : against a role in organelle cation homeostasis

Physical Exercise–Induced Hypoglycemia Caused by Failed Silencing of Monocarboxylate Transporter 1 in Pancreatic β Cells

Stimulated Ca2+ influx raises mitochondrial free Ca2+ to supramicromolar levels in a pancreatic beta-cell line. Possible role in glucose and agonist-induced insulin secretion

Mitochondrial calcium transporting pathways during hypoxia and reoxygenation in single rat cardiomyocytes

Kiss and run exocytosis of dense core secretory vesicles

Ca2+ stores in insulin-secreting cells : lack of effect of cADP ribose

Low lactate dehydrogenase and high mitochondrial glycerol phosphate dehydrogenase in pancreatic beta cells: potential role in nutrient sensing

Regulation of pyruvate dehydrogenase by insulin and polyamines within electropermeabilized fat-cells and isolated mitochondria

Effects of insulin and guanosine 5'-[γ-thio]triphosphate on fatty acid synthesis and lipolysis within electropermeabilized fat-cells

Ca2+-Induced Ca2+ Release in Pancreatic Islet β-Cells: Critical Evaluation of the Use of Endoplasmic Reticulum-Targeted “Cameleons”

Ablation of AMP-activated protein kinase α1 and α2 from mouse pancreatic beta cells and RIP2. Cre neurons suppresses insulin release in vivo

Regulation of the pyruvate dehydrogenase complex by Ca2+ within toluene-permeabilized heart mitochondria

Effects of protein phosphatase inhibitors on the regulation of insulin-sensitive enzymes within rat epidimal fat-pads and cells

Regulation of mitochondrial glycerol-phosphate dehydrogenase by Ca2+ within electropermeabilized insulin-secreting cells (INS-1)

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