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The phosphatidylinositol 3-kinase/Akt and c-Jun N-terminal kinase signaling in cancer: Alliance or contradiction? (Review)

International journal of oncology, 2015-08, Vol.47 (2), p.429-436

2015

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Oncogenic activity of the regulatory subunit p85β of phosphatidylinositol 3-kinase (PI3K)

Proceedings of the National Academy of Sciences - PNAS, 2014-11, Vol.111 (47), p.16826-16829

2014

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The Hippo pathway integrates PI3K-Akt signals with mechanical and polarity cues to control tissue growth

PLoS biology, 2019-10, Vol.17 (10), p.e3000509-e3000509

2019

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mTOR Links Tumor Immunity and Bone Metabolism: What are the Clinical Implications?

International journal of molecular sciences, 2019-11, Vol.20 (23), p.5841

2019

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ΔNp63α is a common inhibitory target in oncogenic PI3K/Ras/Her2-induced cell motility and tumor metastasis

Proceedings of the National Academy of Sciences - PNAS, 2017-05, Vol.114 (20), p.E3964-E3973

2017

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Conjugation of SUMO to p85 leads to a novel mechanism of PI3K regulation

Oncogene, 2016-06, Vol.35 (22), p.2873-2880

2016

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Staying alive: Metabolic adaptations to quiescence

Cell cycle (Georgetown, Tex.), 2012-05, Vol.11 (9), p.1680-1696

2012

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Endogenous YAP1 activation drives immediate onset of cervical carcinoma in situ in mice

Cancer science, 2020-10, Vol.111 (10), p.3576-3587

2020

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Immuno-oncology agent IPI-549 is a modulator of P-glycoprotein (P-gp, MDR1, ABCB1)-mediated multidrug resistance (MDR) in cancer: In vitro and in vivo

Cancer letters, 2019-02, Vol.442, p.91-103

2019

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Ginsenoside Rh2 Ameliorates Lipopolysaccharide-Induced Acute Lung Injury by Regulating the TLR4/PI3K/Akt/mTOR, Raf-1/MEK/ERK, and Keap1/Nrf2/HO-1 Signaling Pathways in Mice

Nutrients, 2018-09, Vol.10 (9), p.1208

2018

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Oncogenic mutations of p110α isoform of PI 3-kinase upregulate its protein kinase activity

PloS one, 2013-08, Vol.8 (8), p.e71337

2013

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Anticancer compound plumbagin and its molecular targets: a structural insight into the inhibitory mechanisms using computational approaches

PloS one, 2014-02, Vol.9 (2), p.e87309-e87309

2014

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The role of microRNAs involved in PI3‐kinase signaling pathway in colorectal cancer

Journal of cellular physiology, 2019-05, Vol.234 (5), p.5664-5673

2019

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Essential role of Stat3 in PI3K-induced oncogenic transformation

Proceedings of the National Academy of Sciences - PNAS, 2011-08, Vol.108 (32), p.13247-13252

2011

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Structural Characterization and Antioxidant Activity of Polysaccharides from Athyrium multidentatum (Doll.) Ching in d-Galactose-Induced Aging Mice via PI3K/AKT Pathway

Molecules (Basel, Switzerland), 2019-09, Vol.24 (18), p.3364

2019

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Suppression of cell migration by phospholipase C-related catalytically inactive protein-dependent modulation of PI3K signalling

Scientific reports, 2017-07, Vol.7 (1), p.5408-14, Article 5408

2017

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Aldehyde oxidase 1 promoted the occurrence and development of colorectal cancer by up-regulation of expression of CD133

International immunopharmacology, 2020-08, Vol.85, p.106618-106618, Article 106618

2020

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p85β increases phosphoinositide 3-kinase activity and accelerates tumor progression

Cell cycle (Georgetown, Tex.), 2012-10, Vol.11 (19), p.3523-3524

2012

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PI3-kinase γ promotes Rap1a-mediated activation of myeloid cell integrin α4β1, leading to tumor inflammation and growth

PloS one, 2013-04, Vol.8 (4), p.e60226-e60226

2013

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DEPDC1B is involved in the proliferation, metastasis, cell cycle arrest and apoptosis of colon cancer cells by regulating NUP37

Molecular medicine reports, 2023-06, Vol.27 (6), Article 126

2023

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PTEN inhibits the invasion and metastasis of gastric cancer via downregulation of FAK expression

Cellular signalling, 2014-05, Vol.26 (5), p.1011-1020

2014

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The circadian rhythm and core gene Period2 regulate the chemotherapy effect and multidrug resistance of ovarian cancer through the PI3K signaling pathway

Bioscience reports, 2020-11, Vol.40 (11), p.1

2020

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Frontline Science: Coincidental null mutation of Csf2rα in a colony of PI3Kγ−/− mice causes alveolar macrophage deficiency and fatal respiratory viral infection

Journal of leukocyte biology, 2017-02, Vol.101 (2), p.367-376

2017

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Isorhapontigenin induced cell growth inhibition and apoptosis by targeting EGFR‐related pathways in prostate cancer

Journal of cellular physiology, 2018-02, Vol.233 (2), p.1104-1119

2018

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The phosphatidylinositol 3-kinase/Akt and c-Jun N-terminal kinase signaling in cancer: Alliance or contradiction? (Review)

Oncogenic activity of the regulatory subunit p85β of phosphatidylinositol 3-kinase (PI3K)

The Hippo pathway integrates PI3K-Akt signals with mechanical and polarity cues to control tissue growth

PI3K-driven HER2 expression is a potential therapeutic target in colorectal cancer stem cells

mTOR Links Tumor Immunity and Bone Metabolism: What are the Clinical Implications?

ΔNp63α is a common inhibitory target in oncogenic PI3K/Ras/Her2-induced cell motility and tumor metastasis

Conjugation of SUMO to p85 leads to a novel mechanism of PI3K regulation

Staying alive: Metabolic adaptations to quiescence

Endogenous YAP1 activation drives immediate onset of cervical carcinoma in situ in mice

Immuno-oncology agent IPI-549 is a modulator of P-glycoprotein (P-gp, MDR1, ABCB1)-mediated multidrug resistance (MDR) in cancer: In vitro and in vivo

Ginsenoside Rh2 Ameliorates Lipopolysaccharide-Induced Acute Lung Injury by Regulating the TLR4/PI3K/Akt/mTOR, Raf-1/MEK/ERK, and Keap1/Nrf2/HO-1 Signaling Pathways in Mice

Oncogenic mutations of p110α isoform of PI 3-kinase upregulate its protein kinase activity

Anticancer compound plumbagin and its molecular targets: a structural insight into the inhibitory mechanisms using computational approaches

The role of microRNAs involved in PI3‐kinase signaling pathway in colorectal cancer

Essential role of Stat3 in PI3K-induced oncogenic transformation

Structural Characterization and Antioxidant Activity of Polysaccharides from Athyrium multidentatum (Doll.) Ching in d-Galactose-Induced Aging Mice via PI3K/AKT Pathway

Suppression of cell migration by phospholipase C-related catalytically inactive protein-dependent modulation of PI3K signalling

Aldehyde oxidase 1 promoted the occurrence and development of colorectal cancer by up-regulation of expression of CD133

p85β increases phosphoinositide 3-kinase activity and accelerates tumor progression

PI3-kinase γ promotes Rap1a-mediated activation of myeloid cell integrin α4β1, leading to tumor inflammation and growth

DEPDC1B is involved in the proliferation, metastasis, cell cycle arrest and apoptosis of colon cancer cells by regulating NUP37

PTEN inhibits the invasion and metastasis of gastric cancer via downregulation of FAK expression

The circadian rhythm and core gene Period2 regulate the chemotherapy effect and multidrug resistance of ovarian cancer through the PI3K signaling pathway

Frontline Science: Coincidental null mutation of Csf2rα in a colony of PI3Kγ−/− mice causes alveolar macrophage deficiency and fatal respiratory viral infection

Isorhapontigenin induced cell growth inhibition and apoptosis by targeting EGFR‐related pathways in prostate cancer

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