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Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus

Nature reviews. Endocrinology, 2019-10, Vol.15 (10), p.569-589

2019

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Metformin: From Mechanisms of Action to Therapies

Cell metabolism, 2014-12, Vol.20 (6), p.953-966

2014

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Beyond Energy Homeostasis: the Expanding Role of AMP-Activated Protein Kinase in Regulating Metabolism

Cell metabolism, 2015-06, Vol.21 (6), p.799-804

2015

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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Nature cell biology, 2011-02, Vol.13 (2), p.132-141

2011

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Promise and challenges for direct small molecule AMPK activators

Biochemical pharmacology, 2018-07, Vol.153, p.147-158

2018

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Cellular and molecular mechanisms of metformin: an overview

Clinical science (1979), 2012-03, Vol.122 (6), p.253-270

2012

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AMP-activated protein kinase suppresses urate crystal-induced inflammation and transduces colchicine effects in macrophages

Annals of the rheumatic diseases, 2016-01, Vol.75 (1), p.286-294

2016

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AMPK Activation Reduces Hepatic Lipid Content by Increasing Fat Oxidation In Vivo

International journal of molecular sciences, 2018-09, Vol.19 (9), p.2826

2018

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AMPKα1 deficiency amplifies proinflammatory myeloid APC activity and CD40 signaling

Journal of leukocyte biology, 2013-12, Vol.94 (6), p.1113-1121

2013

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AMPK Activation Promotes Tight Junction Assembly in Intestinal Epithelial Caco-2 Cells

International journal of molecular sciences, 2019-10, Vol.20 (20), p.5171

2019

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AMPKα1 Regulates Macrophage Skewing at the Time of Resolution of Inflammation during Skeletal Muscle Regeneration

Cell metabolism, 2013-08, Vol.18 (2), p.251-264

2013

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Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status

Circulation research, 2016-08, Vol.119 (5), p.652-665

2016

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AMPK Re-Activation Suppresses Hepatic Steatosis but its Downregulation Does Not Promote Fatty Liver Development

EBioMedicine, 2018-02, Vol.28 (C), p.194-209

2018

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Targeting the AMPK pathway for the treatment of Type 2 diabetes

Frontiers in bioscience, 2009-01, Vol.14 (9), p.3380

2009

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AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo

Cell metabolism, 2013-01, Vol.17 (1), p.113-124

2013

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AMP-Activated Protein Kinase Signalling

International journal of molecular sciences, 2019-02, Vol.20 (3), p.766

2019

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AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation

Nature communications, 2018-01, Vol.9 (1), p.374-17, Article 374

2018

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Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow

Proceedings of the National Academy of Sciences - PNAS, 2017-10, Vol.114 (41), p.E8675-E8684

2017

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Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Science (American Association for the Advancement of Science), 2011-01, Vol.331 (6016), p.456-461

2011

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AMP-activated protein kinase and metabolic control

Handbook of experimental pharmacology, 2011-01 (203), p.303

2011

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Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis

PLoS biology, 2015-12, Vol.13 (12), p.e1002309-e1002309

2015

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AMPK Activation by A-769662 Controls IL-6 Expression in Inflammatory Arthritis

PloS one, 2015-10, Vol.10 (10), p.e0140452

2015

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Metformin suppresses adipogenesis through both AMP-activated protein kinase (AMPK)-dependent and AMPK-independent mechanisms

Molecular and cellular endocrinology, 2017-01, Vol.440, p.57-68

2017

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Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy

Nature communications, 2022-08, Vol.13 (1), p.4444-4444, Article 4444

2022

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GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis

Biochemical journal, 2017-03, Vol.474 (6), p.983-1001

2017

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Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus

Metformin: From Mechanisms of Action to Therapies

Beyond Energy Homeostasis: the Expanding Role of AMP-Activated Protein Kinase in Regulating Metabolism

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Promise and challenges for direct small molecule AMPK activators

Cellular and molecular mechanisms of metformin: an overview

AMP-activated protein kinase suppresses urate crystal-induced inflammation and transduces colchicine effects in macrophages

AMPK Activation Reduces Hepatic Lipid Content by Increasing Fat Oxidation In Vivo

AMPKα1 deficiency amplifies proinflammatory myeloid APC activity and CD40 signaling

AMPK Activation Promotes Tight Junction Assembly in Intestinal Epithelial Caco-2 Cells

AMPKα1 Regulates Macrophage Skewing at the Time of Resolution of Inflammation during Skeletal Muscle Regeneration

Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status

AMPK Re-Activation Suppresses Hepatic Steatosis but its Downregulation Does Not Promote Fatty Liver Development

Targeting the AMPK pathway for the treatment of Type 2 diabetes

AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo

AMP-Activated Protein Kinase Signalling

AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation

Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

AMP-activated protein kinase and metabolic control

Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis

AMPK Activation by A-769662 Controls IL-6 Expression in Inflammatory Arthritis

Metformin suppresses adipogenesis through both AMP-activated protein kinase (AMPK)-dependent and AMPK-independent mechanisms

Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy

GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis

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