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Determination of metarrestin (ML-246) in human plasma for a first-in-human clinical pharmacokinetic application by a simple and efficient uHPLC-MS/MS assay

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2023-05, Vol.1224, p.123738-123738, Article 123738

2023

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Quantitation of the next-generation imipridone ONC206 in human plasma by a simple and sensitive UPLC-MS/MS assay for clinical pharmacokinetic application

Journal of pharmaceutical and biomedical analysis, 2022-05, Vol.213, p.114685-114685, Article 114685

2022

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Development and validation of a simple, selective, and sensitive LC-MS/MS assay for the quantification of remdesivir in human plasma

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2021-05, Vol.1171, p.122641-122641, Article 122641

2021

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Measurement of NLG207 (formerly CRLX101) nanoparticle-bound and released camptothecin in human plasma

Journal of pharmaceutical and biomedical analysis, 2020-03, Vol.181, p.113073-113073, Article 113073

2020

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PBPK modeling-based optimization of site-specific chemo-photodynamic therapy with far-red light-activatable paclitaxel prodrug

Journal of controlled release, 2019-08, Vol.308, p.86-97

2019

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Optimized administration of hetIL-15 expands lymphocytes and minimizes toxicity in rhesus macaques

Cytokine (Philadelphia, Pa.), 2018-08, Vol.108, p.213-224

2018

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A sensitive and rapid ultra high-performance liquid chromatography with tandem mass spectrometric assay for the simultaneous quantitation of cyclophosphamide and the 4-hydroxycyclophosphamide metabolite in human plasma

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2018-06, Vol.1086, p.56-62

2018

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Exosome is a mechanism of intercellular drug transfer: Application of quantitative pharmacology

Journal of controlled release, 2017-12, Vol.268, p.147-158

2017

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A simple and rapid UHPLC–MS/MS method for the quantitation of the dual aurora kinase A/B inhibitor SCH-1473759 in murine plasma

Journal of pharmaceutical and biomedical analysis, 2017-01, Vol.132, p.223-226

2017

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Synthesis of a stable and orally bioavailable englerin analogue

Bioorganic & medicinal chemistry letters, 2016-06, Vol.26 (11), p.2641-2644

2016

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Quantitative determination of mithramycin in human plasma by a novel, sensitive ultra-HPLC–MS/MS method for clinical pharmacokinetic application

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014-11, Vol.970, p.95-101

2014

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A sensitive and robust HPLC assay with fluorescence detection for the quantification of pomalidomide in human plasma for pharmacokinetic analyses

Journal of pharmaceutical and biomedical analysis, 2014-04, Vol.92, p.63-68

2014

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A novel uHPLC–MS/MS method for the quantitation of AZD7451 (AZ12607092) in human plasma

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013-12, Vol.942-943, p.107-112

2013

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A rapid ultra HPLC–MS/MS method for the quantitation and pharmacokinetic analysis of 3-deazaneplanocin A in mice

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013-05, Vol.927, p.142-146

2013

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Development and utilization of a combined LCaUV and LCaMS/MS method for the simultaneous analysis of tegafur and 5-fluorouracil in human plasma to support a phase I clinical study of oral UFTARG/leucovorin

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012-06, Vol.898, p.32-37

2012

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Development and utilization of a combined LC–UV and LC–MS/MS method for the simultaneous analysis of tegafur and 5-fluorouracil in human plasma to support a phase I clinical study of oral UFT®/leucovorin

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012-06, Vol.898, p.32-37

2012

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Quantification of irinotecan, SN38, and SN38G in human and porcine plasma by ultra high-performance liquid chromatography–tandem mass spectrometry and its application to hepatic chemoembolization

Journal of pharmaceutical and biomedical analysis, 2012-03, Vol.62, p.140-148

2012

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A sensitive and rapid ultra HPLC–MS/MS method for the simultaneous detection of clopidogrel and its derivatized active thiol metabolite in human plasma

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012-01, Vol.880 (1), p.132-139

2012

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Determination of metarrestin (ML-246) in human plasma for a first-in-human clinical pharmacokinetic application by a simple and efficient uHPLC-MS/MS assay

Quantitation of the next-generation imipridone ONC206 in human plasma by a simple and sensitive UPLC-MS/MS assay for clinical pharmacokinetic application

Development and validation of a simple, selective, and sensitive LC-MS/MS assay for the quantification of remdesivir in human plasma

Measurement of NLG207 (formerly CRLX101) nanoparticle-bound and released camptothecin in human plasma

PBPK modeling-based optimization of site-specific chemo-photodynamic therapy with far-red light-activatable paclitaxel prodrug

Optimized administration of hetIL-15 expands lymphocytes and minimizes toxicity in rhesus macaques

A sensitive and rapid ultra high-performance liquid chromatography with tandem mass spectrometric assay for the simultaneous quantitation of cyclophosphamide and the 4-hydroxycyclophosphamide metabolite in human plasma

Exosome is a mechanism of intercellular drug transfer: Application of quantitative pharmacology

A simple and rapid UHPLC–MS/MS method for the quantitation of the dual aurora kinase A/B inhibitor SCH-1473759 in murine plasma

Synthesis of a stable and orally bioavailable englerin analogue

Quantitative determination of mithramycin in human plasma by a novel, sensitive ultra-HPLC–MS/MS method for clinical pharmacokinetic application

A sensitive and robust HPLC assay with fluorescence detection for the quantification of pomalidomide in human plasma for pharmacokinetic analyses

A novel uHPLC–MS/MS method for the quantitation of AZD7451 (AZ12607092) in human plasma

A rapid ultra HPLC–MS/MS method for the quantitation and pharmacokinetic analysis of 3-deazaneplanocin A in mice

Development and utilization of a combined LCaUV and LCaMS/MS method for the simultaneous analysis of tegafur and 5-fluorouracil in human plasma to support a phase I clinical study of oral UFTARG/leucovorin

Development and utilization of a combined LC–UV and LC–MS/MS method for the simultaneous analysis of tegafur and 5-fluorouracil in human plasma to support a phase I clinical study of oral UFT®/leucovorin

Quantification of irinotecan, SN38, and SN38G in human and porcine plasma by ultra high-performance liquid chromatography–tandem mass spectrometry and its application to hepatic chemoembolization

A sensitive and rapid ultra HPLC–MS/MS method for the simultaneous detection of clopidogrel and its derivatized active thiol metabolite in human plasma

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