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(−)-Rhazinilam and the diphenylpyridazinone NSC 613241: Two compounds inducing the formation of morphologically similar tubulin spirals but binding apparently to two distinct sites on tubulin

Archives of biochemistry and biophysics, 2016-08, Vol.604, p.63-73

2016

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Insight on [1,3]thiazolo[4,5-e]isoindoles as tubulin polymerization inhibitors

European journal of medicinal chemistry, 2021-02, Vol.212, p.113122, Article 113122

2021

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12,13-Aziridinyl Epothilones. Stereoselective Synthesis of Trisubstituted Olefinic Bonds from Methyl Ketones and Heteroaromatic Phosphonates and Design, Synthesis, and Biological Evaluation of Potent Antitumor Agents

Journal of the American Chemical Society, 2017-05, Vol.139 (21), p.7318-7334

2017

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Total Synthesis of Potent Antitumor Macrolide (-)-Zampanolide: An Oxidative Intramolecular Cyclization-Based Strategy

European journal of organic chemistry, 2012-08, Vol.2012 (22), p.4130-4139

2012

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Synthesis and evaluation of diaryl sulfides and diaryl selenide compounds for antitubulin and cytotoxic activity

Bioorganic & medicinal chemistry letters, 2013-08, Vol.23 (16), p.4669-4673

2013

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Discovery of Biarylaminoquinazolines as Novel Tubulin Polymerization Inhibitors

Journal of medicinal chemistry, 2014-06, Vol.57 (11), p.4598-4605

2014

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New Arylthioindoles and Related Bioisosteres at the Sulfur Bridging Group. 4. Synthesis, Tubulin Polymerization, Cell Growth Inhibition, and Molecular Modeling Studies

Journal of medicinal chemistry, 2009-12, Vol.52 (23), p.7512-7527

2009

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Interactions of Halichondrin B and Eribulin with Tubulin

Journal of chemical information and modeling, 2011-06, Vol.51 (6), p.1393-1404

2011

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Enantioselective Synthesis of (+)-Chamaecypanone C: A Novel Microtubule Inhibitor

Angewandte Chemie (International ed.), 2009-01, Vol.48 (8), p.1494-1497

2009

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Synthesis, antiproliferative activity, and mechanism of action of a series of 2-{[(2 E)-3-phenylprop-2-enoyl]amino}benzamides

European journal of medicinal chemistry, 2011-07, Vol.46 (7), p.2786-2796

2011

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Comparison of the Activities of the Truncated Halichondrin B Analog NSC 707389 (E7389) with Those of the Parent Compound and a Proposed Binding Site on Tubulin

Molecular pharmacology, 2006-12, Vol.70 (6), p.1866-1875

2006

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Synthesis and Biological Evaluation of Dihydrobenzofuran Lignans and Related Compounds as Potential Antitumor Agents that Inhibit Tubulin Polymerization

Journal of medicinal chemistry, 1999-12, Vol.42 (26), p.5475-5481

1999

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Deciphering the key heterocyclic scaffolds in targeting microtubules, kinases and carbonic anhydrases for cancer drug development

Pharmacology & therapeutics (Oxford), 2021-09, Vol.225, p.107860, Article 107860

2021

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Laulimalide and Paclitaxel: A Comparison of Their Effects on Tubulin Assembly and Their Synergistic Action When Present Simultaneously

Molecular pharmacology, 2004-07, Vol.66 (1), p.113-121

2004

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Actin is the primary cellular receptor of bistramide A

Nature chemical biology, 2005-12, Vol.1 (7), p.383-388

2005

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(−)-RHAZINILAM AND THE DIPHENYLPYRIDAZINONE NSC 613241: TWO COMPOUNDS INDUCING THE FORMATION OF MORPHOLOGICALLY SIMILAR TUBULIN SPIRALS BUT BINDING APPARENTLY TO TWO DISTINCT SITES ON TUBULIN1,2

Archives of biochemistry and biophysics, 2016-06, Vol.604, p.63-73

2016

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Intracellular Activation and Deactivation of Tasidotin, an Analog of Dolastatin 15: Correlation with Cytotoxicity

Molecular pharmacology, 2009-01, Vol.75 (1), p.218-226

2009

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Novel Microtubule-Interacting Phenoxy Pyridine and Phenyl Sulfanyl Pyridine Analogues for Cancer Therapy

Journal of medicinal chemistry, 2008-10, Vol.51 (19), p.5953-5957

2008

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Diazonamide A and a Synthetic Structural Analog: Disruptive Effects on Mitosis and Cellular Microtubules and Analysis of Their Interactions with Tubulin

Molecular pharmacology, 2003-06, Vol.63 (6), p.1273-1280

2003

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Synthesis, cytotoxicity, and inhibitory effects on tubulin polymerization of a new 3-heterocyclo substituted 2-styrylquinazolinones

European journal of medicinal chemistry, 2004-04, Vol.39 (4), p.299-304

2004

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Corrigendum to “The interaction of spongistatin 1 with tubulin” [Arch. Biochem. Biophys. 727 (2022) 109296 (7 pages)]

Archives of biochemistry and biophysics, 2022-11, Vol.730, p.109412-109412, Article 109412

2022

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Pyrrolo[2′,3′:3,4]cyclohepta[1,2‑d][1,2]oxazoles, a New Class of Antimitotic Agents Active against Multiple Malignant Cell Types

Journal of medicinal chemistry, 2020-10, Vol.63 (20), p.12023-12042

2020

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Drug-Linker Constructs Bearing Unique Dual-Mechanism Tubulin Binding Payloads Tethered through Cleavable and Non-Cleavable Linkers

Tetrahedron, 2024-11, p.134350, Article 134350

2024

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Identification of pyrrolo[3′,4’:3,4]cyclohepta[1,2-d][1,2]oxazoles as promising new candidates for the treatment of lymphomas

European journal of medicinal chemistry, 2023-06, Vol.254, p.115372-115372, Article 115372

2023

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(−)-Rhazinilam and the diphenylpyridazinone NSC 613241: Two compounds inducing the formation of morphologically similar tubulin spirals but binding apparently to two distinct sites on tubulin

Insight on [1,3]thiazolo[4,5-e]isoindoles as tubulin polymerization inhibitors

12,13-Aziridinyl Epothilones. Stereoselective Synthesis of Trisubstituted Olefinic Bonds from Methyl Ketones and Heteroaromatic Phosphonates and Design, Synthesis, and Biological Evaluation of Potent Antitumor Agents

Total Synthesis of Potent Antitumor Macrolide (-)-Zampanolide: An Oxidative Intramolecular Cyclization-Based Strategy

Toward Highly Potent Cancer Agents by Modulating the C‑2 Group of the Arylthioindole Class of Tubulin Polymerization Inhibitors

Synthesis and evaluation of diaryl sulfides and diaryl selenide compounds for antitubulin and cytotoxic activity

Discovery of Biarylaminoquinazolines as Novel Tubulin Polymerization Inhibitors

New Arylthioindoles and Related Bioisosteres at the Sulfur Bridging Group. 4. Synthesis, Tubulin Polymerization, Cell Growth Inhibition, and Molecular Modeling Studies

Interactions of Halichondrin B and Eribulin with Tubulin

Enantioselective Synthesis of (+)-Chamaecypanone C: A Novel Microtubule Inhibitor

Synthesis, antiproliferative activity, and mechanism of action of a series of 2-{[(2 E)-3-phenylprop-2-enoyl]amino}benzamides

Comparison of the Activities of the Truncated Halichondrin B Analog NSC 707389 (E7389) with Those of the Parent Compound and a Proposed Binding Site on Tubulin

Synthesis and Biological Evaluation of Dihydrobenzofuran Lignans and Related Compounds as Potential Antitumor Agents that Inhibit Tubulin Polymerization

Deciphering the key heterocyclic scaffolds in targeting microtubules, kinases and carbonic anhydrases for cancer drug development

Laulimalide and Paclitaxel: A Comparison of Their Effects on Tubulin Assembly and Their Synergistic Action When Present Simultaneously

Actin is the primary cellular receptor of bistramide A

(−)-RHAZINILAM AND THE DIPHENYLPYRIDAZINONE NSC 613241: TWO COMPOUNDS INDUCING THE FORMATION OF MORPHOLOGICALLY SIMILAR TUBULIN SPIRALS BUT BINDING APPARENTLY TO TWO DISTINCT SITES ON TUBULIN1,2

Intracellular Activation and Deactivation of Tasidotin, an Analog of Dolastatin 15: Correlation with Cytotoxicity

Novel Microtubule-Interacting Phenoxy Pyridine and Phenyl Sulfanyl Pyridine Analogues for Cancer Therapy

Diazonamide A and a Synthetic Structural Analog: Disruptive Effects on Mitosis and Cellular Microtubules and Analysis of Their Interactions with Tubulin

Synthesis, cytotoxicity, and inhibitory effects on tubulin polymerization of a new 3-heterocyclo substituted 2-styrylquinazolinones

Corrigendum to “The interaction of spongistatin 1 with tubulin” [Arch. Biochem. Biophys. 727 (2022) 109296 (7 pages)]

Pyrrolo[2′,3′:3,4]cyclohepta[1,2‑d][1,2]oxazoles, a New Class of Antimitotic Agents Active against Multiple Malignant Cell Types

Drug-Linker Constructs Bearing Unique Dual-Mechanism Tubulin Binding Payloads Tethered through Cleavable and Non-Cleavable Linkers

Identification of pyrrolo[3′,4’:3,4]cyclohepta[1,2-d][1,2]oxazoles as promising new candidates for the treatment of lymphomas

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