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Human toxoplasmosis–Searching for novel chemotherapeutics

Biomedicine & pharmacotherapy, 2016-08, Vol.82, p.677-684

2016

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Synthesis and In Vitro Anti- Toxoplasma gondii Activity of Novel Thiazolidin-4-one Derivatives

Molecules (Basel, Switzerland), 2019-08, Vol.24 (17), p.3029

2019

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Lactic Acid Bacteria-Derived Postbiotics as Adjunctive Agents in Breast Cancer Treatment to Boost the Antineoplastic Effect of a Conventional Therapeutic Comprising Tamoxifen and a New Drug Candidate: An Aziridine-Hydrazide Hydrazone Derivative

Molecules (Basel, Switzerland), 2024-05, Vol.29 (10), p.2292

2024

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Evaluation of long-term immunity and protection against T. gondii after immunization with multivalent recombinant chimeric T. gondii proteins

Scientific reports, 2023-08, Vol.13 (1), p.12976-12976, Article 12976

2023

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4-Arylthiosemicarbazide Derivatives as Toxoplasmic Aromatic Amino Acid Hydroxylase Inhibitors and Anti-inflammatory Agents

International journal of molecular sciences, 2022-03, Vol.23 (6), p.3213

2022

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Inhibition of Toxoplasma gondii by 1,2,4-triazole-based compounds: marked improvement in selectivity relative to the standard therapy pyrimethamine and sulfadiazine

Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.2621-2634

2022

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TZD-Based Hybrid Molecules Act as Dual Anti- Mycobacterium tuberculosis and Anti- Toxoplasma gondii Agents

International journal of molecular sciences, 2023-01, Vol.24 (3), p.2069

2023

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4-Arylthiosemicarbazide derivatives as a new class of tyrosinase inhibitors and anti-Toxoplasma gondii agents

Journal of enzyme inhibition and medicinal chemistry, 2021-01, Vol.36 (1), p.1145-1164

2021

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Behavioral changes in mice caused by Toxoplasma gondii invasion of brain

Parasitology research (1987), 2012-07, Vol.111 (1), p.53-58

2012

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The first study on the usefulness of recombinant tetravalent chimeric proteins containing fragments of SAG2, GRA1, ROP1 and AMA1 antigens in the detection of specific anti-Toxoplasma gondii antibodies in mouse and human sera

PloS one, 2019-06, Vol.14 (6), p.e0217866-e0217866

2019

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Systematic Identification of Thiosemicarbazides for Inhibition of Toxoplasma gondii Growth In Vitro

Molecules (Basel, Switzerland), 2019-02, Vol.24 (3), p.614

2019

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Antifungal effect of 4-arylthiosemicarbazides against Candida species. Search for molecular basis of antifungal activity of thiosemicarbazide derivatives

Journal of molecular modeling, 2012-09, Vol.18 (9), p.4159-4170

2012

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The functional response of human monocyte-derived macrophages to serum amyloid A and Mycobacterium tuberculosis infection

Frontiers in immunology, 2023-09, Vol.14, p.1238132-1238132

2023

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Discovery of Potent and Selective Halogen-Substituted Imidazole-Thiosemicarbazides for Inhibition of Toxoplasma gondii Growth In Vitro via Structure-Based Design

Molecules (Basel, Switzerland), 2019-04, Vol.24 (8), p.1618

2019

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C5a-Preactivated Neutrophils Are Critical for Autoimmune-Induced Astrocyte Dysregulation in Neuromyelitis Optica Spectrum Disorder

Frontiers in immunology, 2018-07, Vol.9, p.1694-1694

2018

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Triazole-based compound as a candidate to develop novel medicines to treat toxoplasmosis

Antimicrobial agents and chemotherapy, 2014-12, Vol.58 (12), p.7583-7585

2014

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1,4-Disubstituted thiosemicarbazide derivatives are potent inhibitors of Toxoplasma gondii proliferation

Molecules (Basel, Switzerland), 2014-07, Vol.19 (7), p.9926-9943

2014

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Toxoplasma gondii Recombinant antigen AMA1: Diagnostic Utility of Protein Fragments for the Detection of IgG and IgM Antibodies

Pathogens (Basel), 2020-01, Vol.9 (1), p.43

2020

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Human toxoplasmosis: a comparative evaluation of the diagnostic potential of recombinant Toxoplasma gondii ROP5 and ROP18 antigens

Journal of medical microbiology, 2015-10, Vol.64 (10), p.1201-1207

2015

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The Immunogenic and Immunoprotective Activities of Recombinant Chimeric T. gondii Proteins Containing AMA1 Antigen Fragments

Vaccines (Basel), 2020-12, Vol.8 (4), p.724

2020

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The Impact of the Antigenic Composition of Chimeric Proteins on Their Immunoprotective Activity against Chronic Toxoplasmosis in Mice

Vaccines (Basel), 2019-10, Vol.7 (4), p.154

2019

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Toxoplasma gondii: The immunogenic and protective efficacy of recombinant ROP2 and ROP4 rhoptry proteins in murine experimental toxoplasmosis

Experimental parasitology, 2009-09, Vol.123 (1), p.81-89

2009

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Phytoecdysteroids as modulators of the Toxoplasma gondii growth rate in human and mouse cells

Parasites & vectors, 2015-08, Vol.8 (1), p.422-422, Article 422

2015

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Enhanced Solubility and Bioavailability of Clotrimazole in Aqueous Solutions with Hydrophobized Hyperbranched Polyglycidol for Improved Antifungal Activity

ACS applied materials & interfaces, 2024-04, Vol.16 (15), p.18434-18448

2024

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Conformational preference of potassium salts of N-acylhydrazinecarbodithioates with antifungal activity. Combined experimental and theoretical approach

Current computer-aided drug design, 2014-01, Vol.10 (3), p.205

2014

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Human toxoplasmosis–Searching for novel chemotherapeutics

Synthesis and In Vitro Anti- Toxoplasma gondii Activity of Novel Thiazolidin-4-one Derivatives

Lactic Acid Bacteria-Derived Postbiotics as Adjunctive Agents in Breast Cancer Treatment to Boost the Antineoplastic Effect of a Conventional Therapeutic Comprising Tamoxifen and a New Drug Candidate: An Aziridine-Hydrazide Hydrazone Derivative

Evaluation of long-term immunity and protection against T. gondii after immunization with multivalent recombinant chimeric T. gondii proteins

4-Arylthiosemicarbazide Derivatives as Toxoplasmic Aromatic Amino Acid Hydroxylase Inhibitors and Anti-inflammatory Agents

Inhibition of Toxoplasma gondii by 1,2,4-triazole-based compounds: marked improvement in selectivity relative to the standard therapy pyrimethamine and sulfadiazine

TZD-Based Hybrid Molecules Act as Dual Anti- Mycobacterium tuberculosis and Anti- Toxoplasma gondii Agents

4-Arylthiosemicarbazide derivatives as a new class of tyrosinase inhibitors and anti-Toxoplasma gondii agents

Behavioral changes in mice caused by Toxoplasma gondii invasion of brain

The first study on the usefulness of recombinant tetravalent chimeric proteins containing fragments of SAG2, GRA1, ROP1 and AMA1 antigens in the detection of specific anti-Toxoplasma gondii antibodies in mouse and human sera

Systematic Identification of Thiosemicarbazides for Inhibition of Toxoplasma gondii Growth In Vitro

Antifungal effect of 4-arylthiosemicarbazides against Candida species. Search for molecular basis of antifungal activity of thiosemicarbazide derivatives

The functional response of human monocyte-derived macrophages to serum amyloid A and Mycobacterium tuberculosis infection

Discovery of Potent and Selective Halogen-Substituted Imidazole-Thiosemicarbazides for Inhibition of Toxoplasma gondii Growth In Vitro via Structure-Based Design

C5a-Preactivated Neutrophils Are Critical for Autoimmune-Induced Astrocyte Dysregulation in Neuromyelitis Optica Spectrum Disorder

Triazole-based compound as a candidate to develop novel medicines to treat toxoplasmosis

1,4-Disubstituted thiosemicarbazide derivatives are potent inhibitors of Toxoplasma gondii proliferation

Toxoplasma gondii Recombinant antigen AMA1: Diagnostic Utility of Protein Fragments for the Detection of IgG and IgM Antibodies

Human toxoplasmosis: a comparative evaluation of the diagnostic potential of recombinant Toxoplasma gondii ROP5 and ROP18 antigens

The Immunogenic and Immunoprotective Activities of Recombinant Chimeric T. gondii Proteins Containing AMA1 Antigen Fragments

The Impact of the Antigenic Composition of Chimeric Proteins on Their Immunoprotective Activity against Chronic Toxoplasmosis in Mice

Toxoplasma gondii: The immunogenic and protective efficacy of recombinant ROP2 and ROP4 rhoptry proteins in murine experimental toxoplasmosis

Phytoecdysteroids as modulators of the Toxoplasma gondii growth rate in human and mouse cells

Enhanced Solubility and Bioavailability of Clotrimazole in Aqueous Solutions with Hydrophobized Hyperbranched Polyglycidol for Improved Antifungal Activity

Conformational preference of potassium salts of N-acylhydrazinecarbodithioates with antifungal activity. Combined experimental and theoretical approach

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