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The Ubiquitin Ligase TRIP12 Limits PARP1 Trapping and Constrains PARP Inhibitor Efficiency

Cell reports (Cambridge), 2020-08, Vol.32 (5), p.107985-107985, Article 107985

2020

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Analysis of PARP inhibitor toxicity by multidimensional fluorescence microscopy reveals mechanisms of sensitivity and resistance

Nature communications, 2018-07, Vol.9 (1), p.2678-16, Article 2678

2018

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Replication-Coupled Dilution of H4K20me2 Guides 53BP1 to Pre-replicative Chromatin

Cell reports (Cambridge), 2017-05, Vol.19 (9), p.1819-1831

2017

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Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins

Nature communications, 2020-10, Vol.11 (1), p.5199-5199, Article 5199

2020

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Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases

Nature structural & molecular biology, 2013-04, Vol.20 (4), p.502-507

2013

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RPA shields inherited DNA lesions for post-mitotic DNA synthesis

Nature communications, 2021-06, Vol.12 (1), p.3827-3827, Article 3827

2021

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Pharmacological Inhibition of Poly(ADP-Ribose) Polymerases Improves Fitness and Mitochondrial Function in Skeletal Muscle

Cell metabolism, 2014-06, Vol.19 (6), p.1034-1041

2014

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CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks

Nature communications, 2020-11, Vol.11 (1), p.5775-19, Article 5775

2020

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DNA polymerase δ-interacting protein 2 is a processivity factor for DNA polymerase λ during 8-oxo-7,8-dihydroguanine bypass

Proceedings of the National Academy of Sciences - PNAS, 2013-11, Vol.110 (47), p.18850-18855

2013

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Impact of ribonucleotide incorporation by DNA polymerases β and λ on oxidative base excision repair

Nature communications, 2016-02, Vol.7 (1), p.10805-10805, Article 10805

2016

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Phase separation of 53BP1 determines liquid‐like behavior of DNA repair compartments

The EMBO journal, 2019-08, Vol.38 (16), p.e101379-n/a

2019

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Transcription coactivator p300 binds PCNA and may have a role in DNA repair synthesis

Nature (London), 2001-03, Vol.410 (6826), p.387-391

2001

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Basal CHK1 activity safeguards its stability to maintain intrinsic S-phase checkpoint functions

The Journal of cell biology, 2019-09, Vol.218 (9), p.2865-2875

2019

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Phase separation properties of RPA combine high-affinity ssDNA binding with dynamic condensate functions at telomeres

Nature structural & molecular biology, 2023-04, Vol.30 (4), p.451-462

2023

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Efficient Pre-mRNA Cleavage Prevents Replication-Stress-Associated Genome Instability

Molecular cell, 2019-02, Vol.73 (4), p.670-683.e12

2019

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Comprehensive ADP‐ribosylome analysis identifies tyrosine as an ADP‐ribose acceptor site

EMBO reports, 2018-08, Vol.19 (8), p.n/a

2018

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Examining protein protein interactions using endogenously tagged yeast arrays: the cross-and-capture system

Genome Research, 2007-12, Vol.17 (12), p.1774-1782

2007

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Phase separation of 53 BP 1 determines liquid‐like behavior of DNA repair compartments

The EMBO journal, 2019-08, Vol.38 (16)

2019

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Ribonucleotide incorporation by human DNA polymerase η impacts translesion synthesis and RNase H2 activity

Nucleic acids research, 2017-03, Vol.45 (5), p.2600

2017

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Regulation of Human MutYH DNA Glycosylase by the E3 Ubiquitin Ligase Mule

The Journal of biological chemistry, 2014-03, Vol.289 (10), p.7049-7058

2014

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Acetylation of Poly(ADP-ribose) Polymerase-1 by p300/CREB-binding Protein Regulates Coactivation of NF-κB-dependent Transcription

The Journal of biological chemistry, 2005-12, Vol.280 (49), p.40450-40464

2005

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Transcriptional Coactivation of Nuclear Factor-κB-dependent Gene Expression by p300 Is Regulated by Poly(ADP)-ribose Polymerase-1

The Journal of biological chemistry, 2003-11, Vol.278 (46), p.45145-45153

2003

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Arginine methyltransferase CARM1 is a promoter-specific regulator of NF-κB-dependent gene expression

The EMBO journal, 2005-01, Vol.24 (1), p.85-96

2005

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The Enzymatic and DNA Binding Activity of PARP-1 Are Not Required for NF-κB Coactivator Function

The Journal of biological chemistry, 2001-12, Vol.276 (49), p.45588-45597

2001

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DNA polymerase ?[delta]interacting protein 2 is a processivity factor for DNA polymerase [lamda] during 8-oxo-7,8-dihydroguanine bypass

Proceedings of the National Academy of Sciences - PNAS, 2013-11, Vol.110 (47), p.18850

2013

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The Ubiquitin Ligase TRIP12 Limits PARP1 Trapping and Constrains PARP Inhibitor Efficiency

Analysis of PARP inhibitor toxicity by multidimensional fluorescence microscopy reveals mechanisms of sensitivity and resistance

Replication-Coupled Dilution of H4K20me2 Guides 53BP1 to Pre-replicative Chromatin

Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins

Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases

RPA shields inherited DNA lesions for post-mitotic DNA synthesis

Pharmacological Inhibition of Poly(ADP-Ribose) Polymerases Improves Fitness and Mitochondrial Function in Skeletal Muscle

CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks

DNA polymerase δ-interacting protein 2 is a processivity factor for DNA polymerase λ during 8-oxo-7,8-dihydroguanine bypass

Impact of ribonucleotide incorporation by DNA polymerases β and λ on oxidative base excision repair

Phase separation of 53BP1 determines liquid‐like behavior of DNA repair compartments

Transcription coactivator p300 binds PCNA and may have a role in DNA repair synthesis

Basal CHK1 activity safeguards its stability to maintain intrinsic S-phase checkpoint functions

Phase separation properties of RPA combine high-affinity ssDNA binding with dynamic condensate functions at telomeres

Efficient Pre-mRNA Cleavage Prevents Replication-Stress-Associated Genome Instability

Comprehensive ADP‐ribosylome analysis identifies tyrosine as an ADP‐ribose acceptor site

Examining protein protein interactions using endogenously tagged yeast arrays: the cross-and-capture system

Phase separation of 53 BP 1 determines liquid‐like behavior of DNA repair compartments

Ribonucleotide incorporation by human DNA polymerase η impacts translesion synthesis and RNase H2 activity

Regulation of Human MutYH DNA Glycosylase by the E3 Ubiquitin Ligase Mule

Acetylation of Poly(ADP-ribose) Polymerase-1 by p300/CREB-binding Protein Regulates Coactivation of NF-κB-dependent Transcription

Transcriptional Coactivation of Nuclear Factor-κB-dependent Gene Expression by p300 Is Regulated by Poly(ADP)-ribose Polymerase-1

Arginine methyltransferase CARM1 is a promoter-specific regulator of NF-κB-dependent gene expression

The Enzymatic and DNA Binding Activity of PARP-1 Are Not Required for NF-κB Coactivator Function

DNA polymerase ?[delta]interacting protein 2 is a processivity factor for DNA polymerase [lamda] during 8-oxo-7,8-dihydroguanine bypass

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