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Candidate pharmacological treatments for substance use disorder and suicide identified by gene co‐expression network‐based drug repositioning

American journal of medical genetics. Part B, Neuropsychiatric genetics, 2021-04, Vol.186 (3), p.193-206

2021

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Identification of shared risk loci and pathways for bipolar disorder and schizophrenia

PloS one, 2017-02, Vol.12 (2), p.e0171595

2017

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Cannabinoid receptor 1 gene (CNR1) and susceptibility to a quantitative phenotype for hebephrenic schizophrenia

American journal of medical genetics. Part B, Neuropsychiatric genetics, 2008-04, Vol.147B (3), p.279-284

2008

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Interplay between Schizophrenia Polygenic Risk Score and Childhood Adversity in First-Presentation Psychotic Disorder: A Pilot Study

PloS one, 2016-09, Vol.11 (9), p.e0163319

2016

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Convergent genomic and pharmacological evidence of PI3K/GSK3 signaling alterations in neurons from schizophrenia patients

Neuropsychopharmacology (New York, N.Y.), 2021-02, Vol.46 (3), p.673-682

2021

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Differential neuregulin 1 cleavage in the prefrontal cortex and hippocampus in schizophrenia and bipolar disorder: preliminary findings

PloS one, 2012-05, Vol.7 (5), p.e36431-e36431

2012

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Structural and Functional Brain Correlates of Cognitive Impairment in Euthymic Patients with Bipolar Disorder

PloS one, 2016-07, Vol.11 (7), p.e0158867-e0158867

2016

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Methionine sulfoxide reductase: A novel schizophrenia candidate gene

American journal of medical genetics. Part B, Neuropsychiatric genetics, 2009-03, Vol.150B (2), p.219-225

2009

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Catechol-O-Methyltransferase moderates effect of stress mindset on affect and cognition

PloS one, 2018-04, Vol.13 (4), p.e0195883

2018

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STEP levels are unchanged in pre-frontal cortex and associative striatum in post-mortem human brain samples from subjects with schizophrenia, bipolar disorder and major depressive disorder

PloS one, 2015-03, Vol.10 (3), p.e0121744-e0121744

2015

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The association between negative symptoms, psychotic experiences and later schizophrenia: a population-based longitudinal study

PloS one, 2015-03, Vol.10 (3), p.e0119852-e0119852

2015

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Clozapine-induced mitochondria alterations and inflammation in brain and insulin-responsive cells

PloS one, 2013-03, Vol.8 (3), p.e59012

2013

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Reduced CYFIP1 in Human Neural Progenitors Results in Dysregulation of Schizophrenia and Epilepsy Gene Networks

PloS one, 2016-01, Vol.11 (1), p.e0148039

2016

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Anhedonia in cocaine use disorder is associated with inflammatory gene expression

PloS one, 2018-11, Vol.13 (11), p.e0207231

2018

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GAD2 Alternative Transcripts in the Human Prefrontal Cortex, and in Schizophrenia and Affective Disorders

PloS one, 2016-02, Vol.11 (2), p.e0148558-e0148558

2016

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Unique Effects of Acute Aripiprazole Treatment on the Dopamine D2 Receptor Downstream cAMP-PKA and Akt-GSK3β Signalling Pathways in Rats

PloS one, 2015-07, Vol.10 (7), p.e0132722-e0132722

2015

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Disturbances in Hypothalamic-Pituitary-Adrenal Axis and Immunological Activity Differentiating between Unipolar and Bipolar Depressive Episodes

PloS one, 2015-07, Vol.10 (7), p.e0133898-e0133898

2015

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Validation of the German Version of the Social Functioning Scale (SFS) for schizophrenia

PloS one, 2015-04, Vol.10 (4), p.e0121807-e0121807

2015

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The β isotypes of tubulin in neuronal differentiation

Cytoskeleton (Hoboken, N.J.), 2010-07, Vol.67 (7), p.431-441

2010

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Metabolomic profiling of schizophrenia patients at risk for metabolic syndrome

The international journal of neuropsychopharmacology, 2014-08, Vol.17 (8), p.1139-1148

2014

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Decreased chloride channel expression in the dorsolateral prefrontal cortex in schizophrenia

PloS one, 2015-03, Vol.10 (3), p.e0123158-e0123158

2015

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Meta-Analysis-Based Preliminary Exploration of the Connection between ATDILI and Schizophrenia by GSTM1/T1 Gene Polymorphisms

PloS one, 2015-06, Vol.10 (6), p.e0128643-e0128643

2015

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A putatively functional polymorphism in the HTR2C gene is associated with depressive symptoms in white females reporting significant life stress

PloS one, 2014-12, Vol.9 (12), p.e114451-e114451

2014

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A human stem cell-derived neuronal model of morphine exposure reflects brain dysregulation in opioid use disorder: Transcriptomic and epigenetic characterization of postmortem-derived iPSC neurons

Frontiers in psychiatry, 2023-02, Vol.14, p.1070556

2023

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MicroRNA-mRNA networks are dysregulated in opioid use disorder postmortem brain: Further evidence for opioid-induced neurovascular alterations

Frontiers in psychiatry, 2023-01, Vol.13, p.1025346-1025346

2023

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Candidate pharmacological treatments for substance use disorder and suicide identified by gene co‐expression network‐based drug repositioning

Identification of shared risk loci and pathways for bipolar disorder and schizophrenia

Cannabinoid receptor 1 gene (CNR1) and susceptibility to a quantitative phenotype for hebephrenic schizophrenia

Interplay between Schizophrenia Polygenic Risk Score and Childhood Adversity in First-Presentation Psychotic Disorder: A Pilot Study

Convergent genomic and pharmacological evidence of PI3K/GSK3 signaling alterations in neurons from schizophrenia patients

Differential neuregulin 1 cleavage in the prefrontal cortex and hippocampus in schizophrenia and bipolar disorder: preliminary findings

Structural and Functional Brain Correlates of Cognitive Impairment in Euthymic Patients with Bipolar Disorder

Methionine sulfoxide reductase: A novel schizophrenia candidate gene

Catechol-O-Methyltransferase moderates effect of stress mindset on affect and cognition

STEP levels are unchanged in pre-frontal cortex and associative striatum in post-mortem human brain samples from subjects with schizophrenia, bipolar disorder and major depressive disorder

The association between negative symptoms, psychotic experiences and later schizophrenia: a population-based longitudinal study

Clozapine-induced mitochondria alterations and inflammation in brain and insulin-responsive cells

Reduced CYFIP1 in Human Neural Progenitors Results in Dysregulation of Schizophrenia and Epilepsy Gene Networks

Anhedonia in cocaine use disorder is associated with inflammatory gene expression

GAD2 Alternative Transcripts in the Human Prefrontal Cortex, and in Schizophrenia and Affective Disorders

Unique Effects of Acute Aripiprazole Treatment on the Dopamine D2 Receptor Downstream cAMP-PKA and Akt-GSK3β Signalling Pathways in Rats

Disturbances in Hypothalamic-Pituitary-Adrenal Axis and Immunological Activity Differentiating between Unipolar and Bipolar Depressive Episodes

Validation of the German Version of the Social Functioning Scale (SFS) for schizophrenia

The β isotypes of tubulin in neuronal differentiation

Metabolomic profiling of schizophrenia patients at risk for metabolic syndrome

Decreased chloride channel expression in the dorsolateral prefrontal cortex in schizophrenia

Meta-Analysis-Based Preliminary Exploration of the Connection between ATDILI and Schizophrenia by GSTM1/T1 Gene Polymorphisms

A putatively functional polymorphism in the HTR2C gene is associated with depressive symptoms in white females reporting significant life stress

A human stem cell-derived neuronal model of morphine exposure reflects brain dysregulation in opioid use disorder: Transcriptomic and epigenetic characterization of postmortem-derived iPSC neurons

MicroRNA-mRNA networks are dysregulated in opioid use disorder postmortem brain: Further evidence for opioid-induced neurovascular alterations

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