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Effects of General Anesthetics on Synaptic Transmission and Plasticity

Current neuropharmacology, 2022-01, Vol.20 (1), p.27-54

2022

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Isoflurane inhibits synaptic vesicle exocytosis through reduced Ca2+influx, not Ca2+-exocytosis coupling

Proceedings of the National Academy of Sciences - PNAS, 2015-09, Vol.112 (38), p.11959-11964

2015

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Volatile anesthetics inhibit presynaptic cGMP signaling to depress presynaptic excitability in rat hippocampal neurons

Neuropharmacology, 2023-12, Vol.240, p.109705-109705, Article 109705

2023

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Towards a Comprehensive Understanding of Anesthetic Mechanisms of Action: A Decade of Discovery

Trends in pharmacological sciences (Regular ed.), 2019-07, Vol.40 (7), p.464-481

2019

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Phytochemicals Perturb Membranes and Promiscuously Alter Protein Function

ACS chemical biology, 2014-08, Vol.9 (8), p.1788-1798

2014

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Relevance of Cortical and Hippocampal Interneuron Functional Diversity to General Anesthetic Mechanisms: A Narrative Review

Frontiers in synaptic neuroscience, 2022-01, Vol.13, p.812905-812905

2022

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Emerging molecular mechanisms of general anesthetic action

Trends in pharmacological sciences (Regular ed.), 2005-10, Vol.26 (10), p.503-510

2005

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Isoflurane Modulates Hippocampal Cornu Ammonis Pyramidal Neuron Excitability by Inhibition of Both Transient and Persistent Sodium Currents in Mice

Anesthesiology (Philadelphia), 2019-07, Vol.131 (1), p.94-104

2019

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Astrocytes Modulate a Specific Paraventricular Thalamus→Prefrontal Cortex Projection to Enhance Consciousness Recovery from Anesthesia

The Journal of neuroscience, 2024-08, Vol.44 (34), p.e1808232024

2024

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Isoflurane reversibly destabilizes hippocampal dendritic spines by an actin-dependent mechanism

PloS one, 2014-07, Vol.9 (7), p.e102978-e102978

2014

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Pharmacology and Physiology for Anesthesia: Foundations and Clinical Application

1, 2013

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Clinical concentrations of chemically diverse general anesthetics minimally affect lipid bilayer properties

Proceedings of the National Academy of Sciences - PNAS, 2017-03, Vol.114 (12), p.3109-3114

2017

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Differential Inhibition of Neuronal Sodium Channel Subtypes by the General Anesthetic Isoflurane

The Journal of pharmacology and experimental therapeutics, 2019-05, Vol.369 (2), p.200-211

2019

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Modulation of dendritic spines by protein phosphatase-1

Advances in pharmacology (1990), 2021-01, Vol.90, p.117-144

2021

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HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain

The Journal of pharmacology and experimental therapeutics, 2013-06, Vol.345 (3), p.363-373

2013

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Comparative Effects of Halogenated Inhaled Anesthetics on Voltage-gated Na+ Channel Function

Anesthesiology (Philadelphia), 2009-03, Vol.110 (3), p.582-590

2009

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Neurotoxicity of general anesthetics: cause for concern?

Anesthesiology (Philadelphia), 2009-12, Vol.111 (6), p.1365-1371

2009

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Isoflurane modulates activation and inactivation gating of the prokaryotic Na + channel NaChBac

The Journal of general physiology, 2017-06, Vol.149 (6), p.623-638

2017

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Sodium channels as targets for volatile anesthetics

Frontiers in pharmacology, 2012-01, Vol.3, p.50-50

2012

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Pharmacology and Physiology for Anesthesia: Foundations and Clinical Application

2nd edition, 2018

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A Common Human Brain-Derived Neurotrophic Factor Polymorphism Leads to Prolonged Depression of Excitatory Synaptic Transmission by Isoflurane in Hippocampal Cultures

Frontiers in molecular neuroscience, 2022-06, Vol.15, p.927149-927149

2022

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Case Scenario: Postoperative Delirium in Elderly Surgical Patients

Anesthesiology (Philadelphia), 2010, Vol.112 (1), p.189-195

2010

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AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release

The EMBO journal, 2010-08, Vol.29 (16), p.2813-2826

2010

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Isoflurane Inhibits the Tetrodotoxin-resistant Voltage-gated Sodium Channel Nav1.8

Anesthesiology (Philadelphia), 2009-09, Vol.111 (3), p.591-599

2009

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Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties

The Journal of general physiology, 2014-12, Vol.144 (6), p.545-560

2014

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Effects of General Anesthetics on Synaptic Transmission and Plasticity

Isoflurane inhibits synaptic vesicle exocytosis through reduced Ca2+influx, not Ca2+-exocytosis coupling

Volatile anesthetics inhibit presynaptic cGMP signaling to depress presynaptic excitability in rat hippocampal neurons

Towards a Comprehensive Understanding of Anesthetic Mechanisms of Action: A Decade of Discovery

Phytochemicals Perturb Membranes and Promiscuously Alter Protein Function

Relevance of Cortical and Hippocampal Interneuron Functional Diversity to General Anesthetic Mechanisms: A Narrative Review

Emerging molecular mechanisms of general anesthetic action

Isoflurane Modulates Hippocampal Cornu Ammonis Pyramidal Neuron Excitability by Inhibition of Both Transient and Persistent Sodium Currents in Mice

Astrocytes Modulate a Specific Paraventricular Thalamus→Prefrontal Cortex Projection to Enhance Consciousness Recovery from Anesthesia

Isoflurane reversibly destabilizes hippocampal dendritic spines by an actin-dependent mechanism

Pharmacology and Physiology for Anesthesia: Foundations and Clinical Application

Clinical concentrations of chemically diverse general anesthetics minimally affect lipid bilayer properties

Differential Inhibition of Neuronal Sodium Channel Subtypes by the General Anesthetic Isoflurane

Modulation of dendritic spines by protein phosphatase-1

HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain

Comparative Effects of Halogenated Inhaled Anesthetics on Voltage-gated Na+ Channel Function

Neurotoxicity of general anesthetics: cause for concern?

Isoflurane modulates activation and inactivation gating of the prokaryotic Na + channel NaChBac

Sodium channels as targets for volatile anesthetics

Pharmacology and Physiology for Anesthesia: Foundations and Clinical Application

A Common Human Brain-Derived Neurotrophic Factor Polymorphism Leads to Prolonged Depression of Excitatory Synaptic Transmission by Isoflurane in Hippocampal Cultures

Case Scenario: Postoperative Delirium in Elderly Surgical Patients

AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release

Isoflurane Inhibits the Tetrodotoxin-resistant Voltage-gated Sodium Channel Nav1.8

Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties

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