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Bisphosphonates: mode of action and pharmacology

Pediatrics (Evanston), 2007-03, Vol.119 Suppl 2 (Supplement_2), p.S150-S162

Russell, R Graham G

2007

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Pharmacology of bisphosphonates

British journal of clinical pharmacology, 2019-06, Vol.85 (6), p.1052-1062

2019

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Pyrophosphate: a key inhibitor of mineralisation

Current opinion in pharmacology, 2016-06, Vol.28, p.57-68

2016

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Design, Synthesis, and Antimicrobial Evaluation of a Novel Bone-Targeting Bisphosphonate-Ciprofloxacin Conjugate for the Treatment of Osteomyelitis Biofilms

Journal of medicinal chemistry, 2017-03, Vol.60 (6), p.2326-2343

2017

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Diagnosis and Management of Paget's Disease of Bone in Adults: A Clinical Guideline

Journal of bone and mineral research, 2019-04, Vol.34 (4), p.579-604

2019

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Differences in intracellular localisation of ANKH mutants that relate to mechanisms of calcium pyrophosphate deposition disease and craniometaphyseal dysplasia

Scientific reports, 2020-05, Vol.10 (1), p.7408-7408, Article 7408

2020

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Reduced colon cancer incidence and mortality in postmenopausal women treated with an oral bisphosphonate—Danish National Register Based Cohort Study

Osteoporosis international, 2012-11, Vol.23 (11), p.2693-2701

2012

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Influence of bone affinity on the skeletal distribution of fluorescently labeled bisphosphonates in vivo

Journal of bone and mineral research, 2012-04, Vol.27 (4), p.835-847

2012

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Fluorescent Bisphosphonate and Carboxyphosphonate Probes: A Versatile Imaging Toolkit for Applications in Bone Biology and Biomedicine

Bioconjugate chemistry, 2016-02, Vol.27 (2), p.329-340

2016

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The Molecular Mechanism of Nitrogen-Containing Bisphosphonates as Antiosteoporosis Drugs

Proceedings of the National Academy of Sciences - PNAS, 2006-05, Vol.103 (20), p.7829-7834

2006

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Functional Characterization of a GGPPS Variant Identified in Atypical Femoral Fracture Patients and Delineation of the Role of GGPPS in Bone‐Relevant Cell Types

Journal of bone and mineral research, 2018-12, Vol.33 (12), p.2091-2098

2018

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The Crystal Structure of Human Geranylgeranyl Pyrophosphate Synthase Reveals a Novel Hexameric Arrangement and Inhibitory Product Binding

The Journal of biological chemistry, 2006-08, Vol.281 (31), p.22004-22012

2006

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Esophageal and gastric cancer incidence and mortality in alendronate users

Journal of bone and mineral research, 2012-03, Vol.27 (3), p.679-686

2012

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Structure–Activity Relationships Among the Nitrogen Containing Bisphosphonates in Clinical Use and Other Analogues: Time-Dependent Inhibition of Human Farnesyl Pyrophosphate Synthase

Journal of medicinal chemistry, 2008-04, Vol.51 (7), p.2187-2195

2008

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Novel mutations in ACVR1 result in atypical features in two fibrodysplasia ossificans progressiva patients

PloS one, 2009-03, Vol.4 (3), p.e5005-e5005

2009

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Eliminating the need for fasting with oral administration of bisphosphonates

Therapeutics and clinical risk management, 2013-01, Vol.9 (default), p.395-402

2013

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Ibandronate in osteoporosis: preclinical data and rationale for intermittent dosing

Osteoporosis international, 2004-06, Vol.15 (6), p.423-433

2004

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Real-Time Impedance-Based Monitoring of the Growth and Inhibition of Osteomyelitis Biofilm Pathogen Staphylococcus aureus Treated with Novel Bisphosphonate-Fluoroquinolone Antimicrobial Conjugates

International journal of molecular sciences, 2023-01, Vol.24 (3), p.1985

2023

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Marion David Francis: 1923–2016

Journal of bone and mineral research, 2016-10, Vol.31 (10), p.1783-1784

2016

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Bisphosphonates: from bench to bedside

Annals of the New York Academy of Sciences, 2006-04, Vol.1068 (1), p.367-401

Russell, R Graham G

2006

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Bisphosphonate Binding Affinity Affects Drug Distribution in Both Intracortical and Trabecular Bone of Rabbits

Calcified tissue international, 2012-03, Vol.90 (3), p.202-210

2012

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The Pharmacological Profile of a Novel Highly Potent Bisphosphonate, OX14 (1‐Fluoro‐2‐(Imidazo‐[1,2‐α]Pyridin‐3‐yl)‐Ethyl‐Bisphosphonate)

Journal of bone and mineral research, 2017-09, Vol.32 (9), p.1860-1869

2017

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Synthesis and Biological Evaluation of α-Halogenated Bisphosphonate and Phosphonocarboxylate Analogues of Risedronate

Journal of medicinal chemistry, 2007-11, Vol.50 (24), p.5967-5975

2007

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Advances in the molecular pharmacology of bone and cancer‐related bone diseases

British journal of pharmacology, 2021-05, Vol.178 (9), p.1889-1890

2021

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Fluorescently Labeled Risedronate and Related Analogues: “Magic Linker” Synthesis

Bioconjugate chemistry, 2008-12, Vol.19 (12), p.2308-2310

2008

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Bisphosphonates: mode of action and pharmacology

Pharmacology of bisphosphonates

Pyrophosphate: a key inhibitor of mineralisation

Design, Synthesis, and Antimicrobial Evaluation of a Novel Bone-Targeting Bisphosphonate-Ciprofloxacin Conjugate for the Treatment of Osteomyelitis Biofilms

Diagnosis and Management of Paget's Disease of Bone in Adults: A Clinical Guideline

Differences in intracellular localisation of ANKH mutants that relate to mechanisms of calcium pyrophosphate deposition disease and craniometaphyseal dysplasia

Reduced colon cancer incidence and mortality in postmenopausal women treated with an oral bisphosphonate—Danish National Register Based Cohort Study

Influence of bone affinity on the skeletal distribution of fluorescently labeled bisphosphonates in vivo

Fluorescent Bisphosphonate and Carboxyphosphonate Probes: A Versatile Imaging Toolkit for Applications in Bone Biology and Biomedicine

The Molecular Mechanism of Nitrogen-Containing Bisphosphonates as Antiosteoporosis Drugs

Functional Characterization of a GGPPS Variant Identified in Atypical Femoral Fracture Patients and Delineation of the Role of GGPPS in Bone‐Relevant Cell Types

The Crystal Structure of Human Geranylgeranyl Pyrophosphate Synthase Reveals a Novel Hexameric Arrangement and Inhibitory Product Binding

Esophageal and gastric cancer incidence and mortality in alendronate users

Structure–Activity Relationships Among the Nitrogen Containing Bisphosphonates in Clinical Use and Other Analogues: Time-Dependent Inhibition of Human Farnesyl Pyrophosphate Synthase

Novel mutations in ACVR1 result in atypical features in two fibrodysplasia ossificans progressiva patients

Eliminating the need for fasting with oral administration of bisphosphonates

Ibandronate in osteoporosis: preclinical data and rationale for intermittent dosing

Real-Time Impedance-Based Monitoring of the Growth and Inhibition of Osteomyelitis Biofilm Pathogen Staphylococcus aureus Treated with Novel Bisphosphonate-Fluoroquinolone Antimicrobial Conjugates

Marion David Francis: 1923–2016

Bisphosphonates: from bench to bedside

Bisphosphonate Binding Affinity Affects Drug Distribution in Both Intracortical and Trabecular Bone of Rabbits

The Pharmacological Profile of a Novel Highly Potent Bisphosphonate, OX14 (1‐Fluoro‐2‐(Imidazo‐[1,2‐α]Pyridin‐3‐yl)‐Ethyl‐Bisphosphonate)

Synthesis and Biological Evaluation of α-Halogenated Bisphosphonate and Phosphonocarboxylate Analogues of Risedronate

Advances in the molecular pharmacology of bone and cancer‐related bone diseases

Fluorescently Labeled Risedronate and Related Analogues: “Magic Linker” Synthesis

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