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Low serum mesothelin in pancreatic cancer patients results from retention of shed mesothelin in the tumor microenvironment

Translational oncology, 2022-07, Vol.21, p.101440-101440, Article 101440

2022

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Tofacitinib to prevent anti-drug antibody formation against LMB-100 immunotoxin in patients with advanced mesothelin-expressing cancers

Frontiers in oncology, 2024, Vol.14, p.1386190-1386190

2024

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Dual mTORC1/2 inhibition compromises cell defenses against exogenous stress potentiating Obatoclax-induced cytotoxicity in atypical teratoid/rhabdoid tumors

Cell death & disease, 2022-04, Vol.13 (4), p.410-14, Article 410

2022

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Defective Cytochrome P450-Catalysed Drug Metabolism in Niemann-Pick Type C Disease

PloS one, 2016-03, Vol.11 (3), p.e0152007-e0152007

2016

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Prospective International Randomized Phase II Study of Low-Dose Abiraterone With Food Versus Standard Dose Abiraterone In Castration-Resistant Prostate Cancer

Journal of clinical oncology, 2018-05, Vol.36 (14), p.1389-1395

2018

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Pharmacokinetics and tolerability of the dual TORC1/2 inhibitor sapanisertib in combination with the MEK inhibitor trametinib in dogs

Frontiers in veterinary science, 2022-12, Vol.9, p.1056408-1056408

2022

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Pulmonary tumor thrombotic microangiopathy and pulmonary veno-occlusive disease in a woman with cervical cancer treated with cediranib and durvalumab

BMC pulmonary medicine, 2018-07, Vol.18 (1), p.112-112, Article 112

2018

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A Quantitative Pharmacology Model of Exosome-Mediated Drug Efflux and Perturbation-Induced Synergy

Pharmaceutics, 2021-06, Vol.13 (7), p.997

2021

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Ibrutinib's off-target mechanism: cause for dose optimization

Cancer biology & therapy, 2021-12, Vol.22 (10-12), p.529-531

2021

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Phase II Randomized Trial of Lenalidomide in Children With Pilocytic Astrocytomas and Optic Pathway Gliomas: A Report From the Children's Oncology Group

Journal of clinical oncology, 2023-06, Vol.41 (18), p.3374-3383

2023

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Opportunities for using in silico‐based extended dosing regimens for monoclonal antibody immune checkpoint inhibitors

British journal of clinical pharmacology, 2020-09, Vol.86 (9), p.1769-1777

2020

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Pomalidomide for Symptomatic Kaposi's Sarcoma in People With and Without HIV Infection: A Phase I/II Study

Journal of clinical oncology, 2016-12, Vol.34 (34), p.4125-4131

2016

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Alcohol and Aldehyde Dehydrogenases Contribute to Sex-Related Differences in Clearance of Zolpidem in Rats

Frontiers in pharmacology, 2016-08, Vol.7, p.260-260

2016

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Phase I trial of belinostat with cisplatin and etoposide in advanced solid tumors, with a focus on neuroendocrine and small cell cancers of the lung

Anti-cancer drugs, 2018-06, Vol.29 (5), p.457-465

2018

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The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response

Pharmacogenetics and genomics, 2013-01, Vol.23 (1), p.1-8

2013

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Diagnosis, staging, and risk stratification in prostate cancer: Utilizing diagnostic tools to avoid unnecessary therapies and side effects

Cancer biology & therapy, 2017-07, Vol.18 (7), p.470-472

2017

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Tissue preservation with mass spectroscopic analysis: Implications for cancer diagnostics

Cancer biology & therapy, 2018-11, Vol.19 (11), p.953-955

2018

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Botryllamide G is an ABCG2 inhibitor that improves lapatinib delivery in mouse brain

Cancer biology & therapy, 2020-03, Vol.21 (3), p.223-230

2020

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Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response

Pharmacogenetics and genomics, 2017-04, Vol.27 (4), p.159-163

2017

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Flow Rate and Apparent Volume of Cerebrospinal Fluid in Rhesus Macaques (Macaca mulatta) Based on the Pharmacokinetics of Intrathecally Administered Inulin

Comparative medicine, 2020-12, Vol.70 (6), p.526-531

2020

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Prolonged low intensity EPOCH-rituximab has improved toxicity in Burkitt lymphoma compared with standard short, high intensity therapy

Cancer biology & therapy, 2014-09, Vol.15 (9), p.1117-1119

2014

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Targeted PI3Kδ inhibition by the small molecule idelalisib as a novel therapy in indolent non-Hodgkin lymphoma

Cancer biology & therapy, 2015-02, Vol.16 (2), p.204-206

2015

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Low serum mesothelin in pancreatic cancer patients results from retention of shed mesothelin in the tumor microenvironment

Tofacitinib to prevent anti-drug antibody formation against LMB-100 immunotoxin in patients with advanced mesothelin-expressing cancers

Dual mTORC1/2 inhibition compromises cell defenses against exogenous stress potentiating Obatoclax-induced cytotoxicity in atypical teratoid/rhabdoid tumors

Preclinical Evaluation of the FGFR-Family Inhibitor Futibatinib for Pediatric Rhabdomyosarcoma

Defective Cytochrome P450-Catalysed Drug Metabolism in Niemann-Pick Type C Disease

Prospective International Randomized Phase II Study of Low-Dose Abiraterone With Food Versus Standard Dose Abiraterone In Castration-Resistant Prostate Cancer

Pharmacokinetics and tolerability of the dual TORC1/2 inhibitor sapanisertib in combination with the MEK inhibitor trametinib in dogs

Pulmonary tumor thrombotic microangiopathy and pulmonary veno-occlusive disease in a woman with cervical cancer treated with cediranib and durvalumab

A Quantitative Pharmacology Model of Exosome-Mediated Drug Efflux and Perturbation-Induced Synergy

Safety and Clinical Activity of the Programmed Death-Ligand 1 Inhibitor Durvalumab in Combination With Poly (ADP-Ribose) Polymerase Inhibitor Olaparib or Vascular Endothelial Growth Factor Receptor 1-3 Inhibitor Cediranib in Women's Cancers: A Dose-Escalation, Phase I Study

Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human interleukin-15 in patients with cancer

Ibrutinib's off-target mechanism: cause for dose optimization

Phase II Randomized Trial of Lenalidomide in Children With Pilocytic Astrocytomas and Optic Pathway Gliomas: A Report From the Children's Oncology Group

Opportunities for using in silico‐based extended dosing regimens for monoclonal antibody immune checkpoint inhibitors

Pomalidomide for Symptomatic Kaposi's Sarcoma in People With and Without HIV Infection: A Phase I/II Study

Alcohol and Aldehyde Dehydrogenases Contribute to Sex-Related Differences in Clearance of Zolpidem in Rats

Phase I trial of belinostat with cisplatin and etoposide in advanced solid tumors, with a focus on neuroendocrine and small cell cancers of the lung

The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response

Diagnosis, staging, and risk stratification in prostate cancer: Utilizing diagnostic tools to avoid unnecessary therapies and side effects

Tissue preservation with mass spectroscopic analysis: Implications for cancer diagnostics

Botryllamide G is an ABCG2 inhibitor that improves lapatinib delivery in mouse brain

Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response

Flow Rate and Apparent Volume of Cerebrospinal Fluid in Rhesus Macaques (Macaca mulatta) Based on the Pharmacokinetics of Intrathecally Administered Inulin

Prolonged low intensity EPOCH-rituximab has improved toxicity in Burkitt lymphoma compared with standard short, high intensity therapy

Targeted PI3Kδ inhibition by the small molecule idelalisib as a novel therapy in indolent non-Hodgkin lymphoma

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