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Investigational drugs in clinical trials for macular degeneration

Expert opinion on investigational drugs, 2022-10, Vol.31 (10), p.1067-1085

2022

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Drugs in Phase II clinical trials for the treatment of age-related macular degeneration

Expert opinion on investigational drugs, 2015-02, Vol.24 (2), p.183-199

2015

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Sialic Acid Mimetic Microglial Sialic Acid-Binding Immunoglobulin-like Lectin Agonism: Potential to Restore Retinal Homeostasis and Regain Visual Function in Age-Related Macular Degeneration

Pharmaceuticals (Basel, Switzerland), 2023-12, Vol.16 (12), p.1735

2023

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Current and investigational drugs for the treatment of diabetic retinopathy

Expert opinion on investigational drugs, 2016-09, Vol.25 (9), p.1011-1022

2016

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Results of the 2-Year Ocriplasmin for Treatment for Symptomatic Vitreomacular Adhesion Including Macular Hole (OASIS) Randomized Trial

Ophthalmology (Rochester, Minn.), 2016-10, Vol.123 (10), p.2232-2247

2016

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Current molecular understanding and future treatment strategies for pathologic ocular neovascularization

Current molecular medicine, 2009-11, Vol.9 (8), p.973

Tolentino, Michael J

2009

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Comprehensive Ocular and Systemic Safety Evaluation of Polysialic Acid-Decorated Immune Modulating Therapeutic Nanoparticles (PolySia-NPs) to Support Entry into First-in-Human Clinical Trials

Pharmaceuticals (Basel, Switzerland), 2024-04, Vol.17 (4), p.481

2024

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Challenges of selecting pharmacotherapy for macular edema the need for better and combination therapies

Expert opinion on pharmacotherapy, 2019-03, Vol.20 (4), p.373-377

2019

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PolySialic Acid Nanoparticles Actuate Complement-Factor-H-Mediated Inhibition of the Alternative Complement Pathway: A Safer Potential Therapy for Age-Related Macular Degeneration

Pharmaceuticals (Basel, Switzerland), 2024-04, Vol.17 (4), p.517

2024

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Treatment of Diabetic Macular Edema with an Inhibitor of Vascular Endothelial-Protein Tyrosine Phosphatase That Activates Tie2

Ophthalmology (Rochester, Minn.), 2015-03, Vol.122 (3), p.545-554

2015

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PolySialic acid-nanoparticles inhibit macrophage mediated inflammation through Siglec agonism: a potential treatment for age related macular degeneration

Frontiers in immunology, 2023, Vol.14, p.1237016-1237016

2023

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Safety of Intravitreal Ocriplasmin for Focal Vitreomacular Adhesion in Patients with Exudative Age-Related Macular Degeneration

Ophthalmology (Rochester, Minn.), 2015-04, Vol.122 (4), p.796-802

2015

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Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model

Molecular vision, 2003-05, Vol.9, p.210-216

2003

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Pathologic features of vascular endothelial growth factor-induced retinopathy in the nonhuman primate

American journal of ophthalmology, 2002-03, Vol.133 (3), p.373-385

2002

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Intravitreal injection of vascular endothelial growth factor small interfering RNA inhibits growth and leakage in a nonhuman primate, laser-induced model of choroidal neovascularization

Retina (Philadelphia, Pa.), 2004-02, Vol.24 (1), p.132

2004

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Inhibition of Retinal Neovascularization by Intraocular Viral-Mediated Delivery of Anti-angiogenic Agents

Molecular therapy, 2002-10, Vol.6 (4), p.490-494

2002

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Systemic rapamycin inhibits retinal and choroidal neovascularization in mice

Molecular vision, 2004-12, Vol.10, p.964-972

2004

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Pharmacological Regulation of Protein Expression from Adeno-Associated Viral Vectors in the Eye

Molecular therapy, 2002-08, Vol.6 (2), p.238-242

2002

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Intravitreous Injections of Vascular Endothelial Growth Factor Produce Retinal Ischemia and Microangiopathy in an Adult Primate

Ophthalmology (Rochester, Minn.), 1996-11, Vol.103 (11), p.1820-1828

1996

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SAT-444 Large-scale community outreach Fibroscan program to detect advanced fibrosis and cirrhosis for early detection of liver cancer

Journal of hepatology, 2024-06, Vol.80, p.S646-S646

2024

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Long-term Outcomes of Adding Lutein/Zeaxanthin and ω-3 Fatty Acids to the AREDS Supplements on Age-Related Macular Degeneration Progression: AREDS2 Report 28

JAMA ophthalmology, 2022-07, Vol.140 (7), p.692

2022

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SCORE Study Report #11

Ophthalmology (Rochester, Minn.), 2011, Vol.118 (7), p.1364-1372

2011

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Intravitreal bevacizumab for macular edema from idiopathic juxtafoveal retinal telangiectasis

Ophthalmic surgery, lasers & imaging, 2007-03, Vol.38 (2), p.164

2007

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Central Serous Chorioretinopathy in Pregnancy

The New England journal of medicine, 2005-08, Vol.353 (7), p.e6

2005

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Retinal Temperature Increase during Transpupillary Thermotherapy: Effects of Pigmentation, Subretinal Blood, and Choroidal Blood Flow

Investigative ophthalmology & visual science, 2004-10, Vol.45 (10), p.3678-3682

2004

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Investigational drugs in clinical trials for macular degeneration

Drugs in Phase II clinical trials for the treatment of age-related macular degeneration

Sialic Acid Mimetic Microglial Sialic Acid-Binding Immunoglobulin-like Lectin Agonism: Potential to Restore Retinal Homeostasis and Regain Visual Function in Age-Related Macular Degeneration

Current and investigational drugs for the treatment of diabetic retinopathy

Results of the 2-Year Ocriplasmin for Treatment for Symptomatic Vitreomacular Adhesion Including Macular Hole (OASIS) Randomized Trial

Current molecular understanding and future treatment strategies for pathologic ocular neovascularization

Comprehensive Ocular and Systemic Safety Evaluation of Polysialic Acid-Decorated Immune Modulating Therapeutic Nanoparticles (PolySia-NPs) to Support Entry into First-in-Human Clinical Trials

Challenges of selecting pharmacotherapy for macular edema the need for better and combination therapies

PolySialic Acid Nanoparticles Actuate Complement-Factor-H-Mediated Inhibition of the Alternative Complement Pathway: A Safer Potential Therapy for Age-Related Macular Degeneration

Treatment of Diabetic Macular Edema with an Inhibitor of Vascular Endothelial-Protein Tyrosine Phosphatase That Activates Tie2

PolySialic acid-nanoparticles inhibit macrophage mediated inflammation through Siglec agonism: a potential treatment for age related macular degeneration

Safety of Intravitreal Ocriplasmin for Focal Vitreomacular Adhesion in Patients with Exudative Age-Related Macular Degeneration

Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model

Pathologic features of vascular endothelial growth factor-induced retinopathy in the nonhuman primate

Intravitreal injection of vascular endothelial growth factor small interfering RNA inhibits growth and leakage in a nonhuman primate, laser-induced model of choroidal neovascularization

Inhibition of Retinal Neovascularization by Intraocular Viral-Mediated Delivery of Anti-angiogenic Agents

Systemic rapamycin inhibits retinal and choroidal neovascularization in mice

Pharmacological Regulation of Protein Expression from Adeno-Associated Viral Vectors in the Eye

Intravitreous Injections of Vascular Endothelial Growth Factor Produce Retinal Ischemia and Microangiopathy in an Adult Primate

SAT-444 Large-scale community outreach Fibroscan program to detect advanced fibrosis and cirrhosis for early detection of liver cancer

Long-term Outcomes of Adding Lutein/Zeaxanthin and ω-3 Fatty Acids to the AREDS Supplements on Age-Related Macular Degeneration Progression: AREDS2 Report 28

SCORE Study Report #11

Intravitreal bevacizumab for macular edema from idiopathic juxtafoveal retinal telangiectasis

Central Serous Chorioretinopathy in Pregnancy

Retinal Temperature Increase during Transpupillary Thermotherapy: Effects of Pigmentation, Subretinal Blood, and Choroidal Blood Flow

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