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Screening and identification of inhibitors of endoplasmic reticulum stress-induced activation of the IRE1α-XBP1 branch

Journal of antibiotics, 2019-12, Vol.72 (12), p.899-905

Tashiro, Etsu

2019

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Functions of cyclin D1 as an oncogene and regulation of cyclin D1 expression

Cancer science, 2007-05, Vol.98 (5), p.629-635

2007

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Bisprenyl naphthoquinone and chlorinated calcimycin congener bearing thiazole ring from an actinomycete of the genus Phytohabitans

Journal of antibiotics, 2022-10, Vol.75 (10), p.542-551

2022

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Androgen receptor antagonists produced by Streptomyces overcome resistance to enzalutamide

Journal of antibiotics, 2021-10, Vol.74 (10), p.706-716

2021

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Involvement of the MEK/ERK pathway in EGF-induced E-cadherin down-regulation

Biochemical and biophysical research communications, 2016-09, Vol.477 (4), p.801-806

2016

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Hybrid molecule between platanic acid and LCL-161 as a yes-associated protein degrader

Journal of biochemistry (Tokyo), 2022-06, Vol.171 (6), p.631-640

2022

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Ktedonoketone and 2’-oxosattabacin, benzenoid metabolites from a thermophilic bacterium Thermosporothrix hazakensis in the phylum Chloroflexi

Journal of antibiotics, 2019-09, Vol.72 (9), p.653-660

2019

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Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA

Nature chemical biology, 2007-09, Vol.3 (9), p.576-583

2007

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Vacuolar H+‐ATPase inhibitors overcome Bcl‐xL‐mediated chemoresistance through restoration of a caspase‐independent apoptotic pathway

Cancer science, 2009-08, Vol.100 (8), p.1460-1467

2009

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Cinnamomum bejolghota Extract Inhibits Colorectal Cancer Cell Metastasis and TGF-β1-Induced Epithelial-Mesenchymal Transition via Smad and Non-Smad Signaling Pathway

Scientia pharmaceutica, 2022-06, Vol.90 (2), p.30

2022

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Target identification of bioactive compounds

Bioorganic & medicinal chemistry, 2012-03, Vol.20 (6), p.1910-1921

2012

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Cyclopeptides from the Mushroom Pathogen Fungus Cladobotryum varium

Journal of natural products (Washington, D.C.), 2021-02, Vol.84 (2), p.327-338

2021

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5‐Lipoxygenase and cysteinyl leukotriene receptor 1 regulate epidermal growth factor‐induced cell migration through Tiam1 upregulation and Rac1 activation

Cancer science, 2014-03, Vol.105 (3), p.290-296

2014

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Generation of incednine derivatives by mutasynthesis

Journal of antibiotics, 2020-11, Vol.73 (11), p.794-797

2020

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Identification of licopyranocoumarin and glycyrurol from herbal medicines as neuroprotective compounds for Parkinson's disease

PloS one, 2014-06, Vol.9 (6), p.e100395-e100395

2014

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Metacycloprodigiosin induced cell death selectively in β-catenin-mutated tumor cells

Journal of antibiotics, 2017-01, Vol.70 (1), p.109-112

2017

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Xanthohumol Impairs Autophagosome Maturation through Direct Inhibition of Valosin-Containing Protein

ACS chemical biology, 2012-05, Vol.7 (5), p.892-900

2012

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Chemical genomic-based pathway analyses for epidermal growth factor-mediated signaling in migrating cancer cells

PloS one, 2014-05, Vol.9 (5), p.e96776-e96776

2014

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Evaluation of drug toxicity profiles based on the phenotypes of ascidian Ciona intestinalis

Biochemical and biophysical research communications, 2015-08, Vol.463 (4), p.656-660

2015

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Protein kinase A inhibition facilitates the antitumor activity of xanthohumol, a valosin‐containing protein inhibitor

Cancer science, 2017-04, Vol.108 (4), p.785-794

2017

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Involvement of 14-3-3 Proteins in the Second Epidermal Growth Factor-induced Wave of Rac1 Activation in the Process of Cell Migration

The Journal of biological chemistry, 2011-11, Vol.286 (45), p.39259-39268

2011

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A chemical genomic study identifying diversity in cell migration signaling in cancer cells

Scientific reports, 2012-11, Vol.2 (1), p.823-823, Article 823

2012

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Napyradiomycin A1, an inhibitor of mitochondrial complexes I and II

Journal of antibiotics, 2012-04, Vol.65 (4), p.211-214

2012

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Inostamycin enhanced TRAIL-induced apoptosis through DR5 upregulation on the cell surface

Journal of antibiotics, 2012-06, Vol.65 (6), p.295-300

2012

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Generation of ‘Unnatural Natural Product’ library and identification of a small molecule inhibitor of XIAP

Bioorganic & medicinal chemistry, 2011-07, Vol.19 (14), p.4377-4385

2011

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Screening and identification of inhibitors of endoplasmic reticulum stress-induced activation of the IRE1α-XBP1 branch

Functions of cyclin D1 as an oncogene and regulation of cyclin D1 expression

Bisprenyl naphthoquinone and chlorinated calcimycin congener bearing thiazole ring from an actinomycete of the genus Phytohabitans

Androgen receptor antagonists produced by Streptomyces overcome resistance to enzalutamide

Involvement of the MEK/ERK pathway in EGF-induced E-cadherin down-regulation

Hybrid molecule between platanic acid and LCL-161 as a yes-associated protein degrader

Ktedonoketone and 2’-oxosattabacin, benzenoid metabolites from a thermophilic bacterium Thermosporothrix hazakensis in the phylum Chloroflexi

Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA

Vacuolar H+‐ATPase inhibitors overcome Bcl‐xL‐mediated chemoresistance through restoration of a caspase‐independent apoptotic pathway

Cinnamomum bejolghota Extract Inhibits Colorectal Cancer Cell Metastasis and TGF-β1-Induced Epithelial-Mesenchymal Transition via Smad and Non-Smad Signaling Pathway

Target identification of bioactive compounds

Cyclopeptides from the Mushroom Pathogen Fungus Cladobotryum varium

5‐Lipoxygenase and cysteinyl leukotriene receptor 1 regulate epidermal growth factor‐induced cell migration through Tiam1 upregulation and Rac1 activation

Generation of incednine derivatives by mutasynthesis

Identification of licopyranocoumarin and glycyrurol from herbal medicines as neuroprotective compounds for Parkinson's disease

Metacycloprodigiosin induced cell death selectively in β-catenin-mutated tumor cells

Xanthohumol Impairs Autophagosome Maturation through Direct Inhibition of Valosin-Containing Protein

Chemical genomic-based pathway analyses for epidermal growth factor-mediated signaling in migrating cancer cells

Evaluation of drug toxicity profiles based on the phenotypes of ascidian Ciona intestinalis

Protein kinase A inhibition facilitates the antitumor activity of xanthohumol, a valosin‐containing protein inhibitor

Involvement of 14-3-3 Proteins in the Second Epidermal Growth Factor-induced Wave of Rac1 Activation in the Process of Cell Migration

A chemical genomic study identifying diversity in cell migration signaling in cancer cells

Napyradiomycin A1, an inhibitor of mitochondrial complexes I and II

Inostamycin enhanced TRAIL-induced apoptosis through DR5 upregulation on the cell surface

Generation of ‘Unnatural Natural Product’ library and identification of a small molecule inhibitor of XIAP

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