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Pharmacokinetics, Disposition, and Biotransformation of [14C]Lenacapavir, a Novel, First-in-Class, Selective Inhibitor of HIV-1 Capsid Function, in Healthy Participants Following a Single Intravenous Infusion

Clinical pharmacokinetics, 2024-02, Vol.63 (2), p.241-253

2024

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Population Pharmacokinetic Analysis of Alirocumab in Healthy Volunteers or Hypercholesterolemic Subjects Using a Michaelis–Menten Approximation of a Target-Mediated Drug Disposition Model—Support for a Biologics License Application Submission: Part I

Clinical pharmacokinetics, 2019-01, Vol.58 (1), p.101-113

2019

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Pharmacogenetics of UGT1A4, UGT2B7 and UGT2B15 and Their Influence on Tamoxifen Disposition in Asian Breast Cancer Patients

Clinical pharmacokinetics, 2016-10, Vol.55 (10), p.1239-1250

2016

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Physiologically Based Pharmacokinetic Modeling of Impaired Carboxylesterase-1 Activity: Effects on Oseltamivir Disposition

Clinical pharmacokinetics, 2014-09, Vol.53 (9), p.825-836

2014

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Contribution of cytochrome P450 2D6 to 3,4- methylenedioxymethamphetamine disposition in humans : Use of paroxetine as a metabolic inhibitor probe

Clinical pharmacokinetics, 2005-01, Vol.44 (6), p.649-660

2005

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Fluoxetine Disposition in Patients with Chronic Hepatitis C Treated with Interferon-α

Clinical pharmacokinetics, 2010-11, Vol.49 (11), p.767-772

2010

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Deposition and disposition of [11C]zanamivir following administration as an intranasal spray. Evaluation with positron emission tomography

Clinical pharmacokinetics, 1999, Vol.36 Suppl 1 (Supplement 1), p.33-39

1999

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Influence of age and cytochrome P450 2C9 genotype on the steady-state disposition of diclofenac and celecoxib

Clinical pharmacokinetics, 2003, Vol.42 (3), p.283-292

2003

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Disposition of ibuprofen in patients with liver cirrhosis : stereochemical considerations

Clinical pharmacokinetics, 1993-08, Vol.25 (2), p.154-163

1993

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Nonparametric expectation maximisation (NPEM) population pharmacokinetic analysis of caffeine disposition from sparse data in adult Caucasians: Systemic caffeine clearance as a biomarker for cytochrome P450 1A2 activity

Clinical pharmacokinetics, 2003-01, Vol.42 (15), p.1393-1409

2003

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Disposition of liposomal daunorubicin during cotreatment with cytarabine in patients with leukaemia

Clinical pharmacokinetics, 2003-01, Vol.42 (9), p.851-862

2003

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Disposition of fleroxacin, a new trifluoroquinolone, and its metabolites : pharmacokinetics in renal failure and influence of haemodialysis

Clinical pharmacokinetics, 1990-07, Vol.19 (1), p.67-79

1990

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The effect of age on the systemic absorption, disposition and pharmacodynamics of bupivacaine after epidural administration

Clinical pharmacokinetics, 1992, Vol.22 (1), p.75-84

1992

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Pharmacokinetics of lignocaine and bupivacaine in surgical patients following epidural administration: simultaneous investigation of absorption and disposition kinetics using stable isotopes

Clinical pharmacokinetics, 1987-09, Vol.13 (3), p.191-203

1987

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Disposition of antipyrine and phenytoin correlated with age and liver volume in man

Clinical pharmacokinetics, 1981-01, Vol.6 (5), p.389-396

1981

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Population Pharmacokinetics of Intravenous Lidocaine in Adults: A Systematic Review

Clinical pharmacokinetics, 2024-05, Vol.63 (5), p.623-643

2024

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Development of a Physiologically Based Pharmacokinetic Population Model for Diabetic Patients and its Application to Understand Disease-drug–drug Interactions

Clinical pharmacokinetics, 2024-06, Vol.63 (6), p.831-845

2024

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A Mechanistic Framework for In Vitro–In Vivo Extrapolation of Liver Membrane Transporters: Prediction of Drug–Drug Interaction Between Rosuvastatin and Cyclosporine

Clinical pharmacokinetics, 2014-01, Vol.53 (1), p.73-87

2014

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Physiologically Based Pharmacokinetic Modeling to Characterize Acetaminophen Pharmacokinetics and N-Acetyl-p-Benzoquinone Imine (NAPQI) Formation in Non-Pregnant and Pregnant Women

Clinical pharmacokinetics, 2020-01, Vol.59 (1), p.97-110

2020

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Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen

Clinical pharmacokinetics, 2016-07, Vol.55 (7), p.833-847

2016

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Age-Related Change in Hepatic Clearance Inferred from Multiple Population Pharmacokinetic Studies: Comparison with Renal Clearance and Their Associations with Organ Weight and Blood Flow

Clinical pharmacokinetics, 2022-02, Vol.61 (2), p.295-305

2022

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Dose-Dependent Bioavailability and CYP3A Inhibition Contribute to Non-Linear Pharmacokinetics of Voriconazole

Clinical pharmacokinetics, 2016-12, Vol.55 (12), p.1535-1545

2016

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Pharmacokinetics of Afatinib, a Selective Irreversible ErbB Family Blocker, in Patients with Advanced Solid Tumours

Clinical pharmacokinetics, 2013-12, Vol.52 (12), p.1101-1109

2013

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Exposure–Toxicity Relationship of Sorafenib in Japanese Patients with Renal Cell Carcinoma and Hepatocellular Carcinoma

Clinical pharmacokinetics, 2014-02, Vol.53 (2), p.185-196

2014

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Population Pharmacokinetic and Covariate Analysis of Apatinib, an Oral Tyrosine Kinase Inhibitor, in Healthy Volunteers and Patients with Solid Tumors

Clinical pharmacokinetics, 2017, Vol.56 (1), p.65-76

2017

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Pharmacokinetics, Disposition, and Biotransformation of [14C]Lenacapavir, a Novel, First-in-Class, Selective Inhibitor of HIV-1 Capsid Function, in Healthy Participants Following a Single Intravenous Infusion

Population Pharmacokinetic Analysis of Alirocumab in Healthy Volunteers or Hypercholesterolemic Subjects Using a Michaelis–Menten Approximation of a Target-Mediated Drug Disposition Model—Support for a Biologics License Application Submission: Part I

Pharmacogenetics of UGT1A4, UGT2B7 and UGT2B15 and Their Influence on Tamoxifen Disposition in Asian Breast Cancer Patients

Physiologically Based Pharmacokinetic Modeling of Impaired Carboxylesterase-1 Activity: Effects on Oseltamivir Disposition

Contribution of cytochrome P450 2D6 to 3,4- methylenedioxymethamphetamine disposition in humans : Use of paroxetine as a metabolic inhibitor probe

Fluoxetine Disposition in Patients with Chronic Hepatitis C Treated with Interferon-α

Deposition and disposition of [11C]zanamivir following administration as an intranasal spray. Evaluation with positron emission tomography

Influence of age and cytochrome P450 2C9 genotype on the steady-state disposition of diclofenac and celecoxib

Disposition of ibuprofen in patients with liver cirrhosis : stereochemical considerations

Nonparametric expectation maximisation (NPEM) population pharmacokinetic analysis of caffeine disposition from sparse data in adult Caucasians: Systemic caffeine clearance as a biomarker for cytochrome P450 1A2 activity

Disposition of liposomal daunorubicin during cotreatment with cytarabine in patients with leukaemia

Disposition of fleroxacin, a new trifluoroquinolone, and its metabolites : pharmacokinetics in renal failure and influence of haemodialysis

The effect of age on the systemic absorption, disposition and pharmacodynamics of bupivacaine after epidural administration

Pharmacokinetics of lignocaine and bupivacaine in surgical patients following epidural administration: simultaneous investigation of absorption and disposition kinetics using stable isotopes

Disposition of antipyrine and phenytoin correlated with age and liver volume in man

Population Pharmacokinetics of Intravenous Lidocaine in Adults: A Systematic Review

Development of a Physiologically Based Pharmacokinetic Population Model for Diabetic Patients and its Application to Understand Disease-drug–drug Interactions

A Mechanistic Framework for In Vitro–In Vivo Extrapolation of Liver Membrane Transporters: Prediction of Drug–Drug Interaction Between Rosuvastatin and Cyclosporine

Physiologically Based Pharmacokinetic Modeling to Characterize Acetaminophen Pharmacokinetics and N-Acetyl-p-Benzoquinone Imine (NAPQI) Formation in Non-Pregnant and Pregnant Women

Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen

Age-Related Change in Hepatic Clearance Inferred from Multiple Population Pharmacokinetic Studies: Comparison with Renal Clearance and Their Associations with Organ Weight and Blood Flow

Dose-Dependent Bioavailability and CYP3A Inhibition Contribute to Non-Linear Pharmacokinetics of Voriconazole

Pharmacokinetics of Afatinib, a Selective Irreversible ErbB Family Blocker, in Patients with Advanced Solid Tumours

Exposure–Toxicity Relationship of Sorafenib in Japanese Patients with Renal Cell Carcinoma and Hepatocellular Carcinoma

Population Pharmacokinetic and Covariate Analysis of Apatinib, an Oral Tyrosine Kinase Inhibitor, in Healthy Volunteers and Patients with Solid Tumors

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