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Live-cell analysis of endogenous GFP-RPB1 uncovers rapid turnover of initiating and promoter-paused RNA Polymerase II

Proceedings of the National Academy of Sciences - PNAS, 2018-05, Vol.115 (19), p.E4368-E4376

2018

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DNA damage-induced transcription stress triggers the genome-wide degradation of promoter-bound Pol II

Nature communications, 2022-06, Vol.13 (1), p.3624-18, Article 3624

2022

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WDR82/PNUTS-PP1 Prevents Transcription-Replication Conflicts by Promoting RNA Polymerase II Degradation on Chromatin

Cell reports (Cambridge), 2020-12, Vol.33 (9), p.108469-108469, Article 108469

2020

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Multimodal Transformers and Their Applications in Drug Target Discovery for Aging and Age-Related Diseases

The journals of gerontology. Series A, Biological sciences and medical sciences, 2024-09, Vol.79 (9)

2024

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Disruption of TTDA results in complete nucleotide excision repair deficiency and embryonic lethality

PLoS genetics, 2013-04, Vol.9 (4), p.e1003431-e1003431

2013

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Maßnahmen & Monitoring: Rücksicht auf Natur und Biodiversität bei der Energiewende

1, 2024

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Traveling Rocky Roads: The Consequences of Transcription-Blocking DNA Lesions on RNA Polymerase II

Journal of molecular biology, 2017-10, Vol.429 (21), p.3146-3155

2017

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MAT2A inhibition combats metabolic and transcriptional reprogramming in cancer

Drug discovery today, 2024-11, Vol.29 (11), p.104189, Article 104189

2024

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Discovery of a Novel and Potent Cyclin-Dependent Kinase 8/19 (CDK8/19) Inhibitor for the Treatment of Cancer

Journal of medicinal chemistry, 2024-05, Vol.67 (10), p.8161-8171

2024

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Discovery of novel MAT2A inhibitors by an allosteric site-compatible fragment growing approach

Bioorganic & medicinal chemistry, 2024-02, Vol.100, p.117633-117633, Article 117633

2024

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Differential processing of RNA polymerase II at DNA damage correlates with transcription-coupled repair syndrome severity

Nucleic acids research, 2024-09, Vol.52 (16), p.9596-9612

2024

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Fluorescently-labelled CPD and 6-4PP photolyases: new tools for live-cell DNA damage quantification and laser-assisted repair

Nucleic acids research, 2019-04, Vol.47 (7), p.3536-3549

2019

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Experimental and Computational Analysis of Newly Identified Pathogenic Mutations in the Creatine Transporter SLC6A8

Journal of molecular biology, 2024-01, Vol.436 (2), p.168383-168383, Article 168383

2024

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Discovery of macrocyclic CDK2/4/6 inhibitors with improved potency and DMPK properties through a highly efficient macrocyclic drug design platform

Bioorganic chemistry, 2024-05, Vol.146, p.107285-107285, Article 107285

2024

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AI-enabled cancer target prioritization with optimal profiles balancing novelty, confidence and commercial tractability

Future Medicine AI, 2024-03, Vol.2 (1)

2024

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Ultra-soft X-ray system for imaging the early cellular responses to X-ray induced DNA damage

Nucleic acids research, 2019-09, Vol.47 (17), p.e100-e100

2019

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C8-glycosphingolipids preferentially insert into tumor cell membranes and promote chemotherapeutic drug uptake

Biochimica et biophysica acta, 2015-08, Vol.1848 (8), p.1656-1670

2015

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Disruption of TTDA Results in Complete Nucleotide Excision Repair Deficiency and Embryonic Lethality: e1003431

PLoS genetics, 2013-04, Vol.9 (4)

2013

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Identification of Leishmania spp. by Molecular Amplification and DNA Sequencing Analysis of a Fragment of rRNA Internal Transcribed Spacer 2

Journal of Clinical Microbiology, 2011-09, Vol.49 (9), p.3143-3149

2011

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Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial

JAMA : the journal of the American Medical Association, 2015-02, Vol.313 (5), p.471

2015

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High homogeneity of MMR deficiency in ovarian cancer

Gynecologic oncology, 2020-03, Vol.156 (3), p.669-675

2020

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Molecular control of endurance training adaptation in male mouse skeletal muscle

Nature metabolism, 2023-11, Vol.5 (11), p.2020-2035

2023

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Detection and Differentiation of Leishmania spp. in Clinical Specimens by Use of a SYBR Green-Based Real-Time PCR Assay

Journal of clinical microbiology, 2017-01, Vol.55 (1), p.281-290

2017

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Integrative Genomic Analyses Reveal an Androgen-Driven Somatic Alteration Landscape in Early-Onset Prostate Cancer

Cancer cell, 2013-02, Vol.23 (2), p.159-170

2013

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Live-cell analysis of endogenous GFP-RPB1 uncovers rapid turnover of initiating and promoter-paused RNA Polymerase II

DNA damage-induced transcription stress triggers the genome-wide degradation of promoter-bound Pol II

WDR82/PNUTS-PP1 Prevents Transcription-Replication Conflicts by Promoting RNA Polymerase II Degradation on Chromatin

Multimodal Transformers and Their Applications in Drug Target Discovery for Aging and Age-Related Diseases

Disruption of TTDA results in complete nucleotide excision repair deficiency and embryonic lethality

Maßnahmen & Monitoring: Rücksicht auf Natur und Biodiversität bei der Energiewende

Traveling Rocky Roads: The Consequences of Transcription-Blocking DNA Lesions on RNA Polymerase II

MAT2A inhibition combats metabolic and transcriptional reprogramming in cancer

Discovery of a Novel and Potent Cyclin-Dependent Kinase 8/19 (CDK8/19) Inhibitor for the Treatment of Cancer

Discovery of novel MAT2A inhibitors by an allosteric site-compatible fragment growing approach

Differential processing of RNA polymerase II at DNA damage correlates with transcription-coupled repair syndrome severity

Fluorescently-labelled CPD and 6-4PP photolyases: new tools for live-cell DNA damage quantification and laser-assisted repair

Experimental and Computational Analysis of Newly Identified Pathogenic Mutations in the Creatine Transporter SLC6A8

Discovery of macrocyclic CDK2/4/6 inhibitors with improved potency and DMPK properties through a highly efficient macrocyclic drug design platform

AI-enabled cancer target prioritization with optimal profiles balancing novelty, confidence and commercial tractability

Ultra-soft X-ray system for imaging the early cellular responses to X-ray induced DNA damage

Publisher Correction: Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability

C8-glycosphingolipids preferentially insert into tumor cell membranes and promote chemotherapeutic drug uptake

Disruption of TTDA Results in Complete Nucleotide Excision Repair Deficiency and Embryonic Lethality: e1003431

Identification of Leishmania spp. by Molecular Amplification and DNA Sequencing Analysis of a Fragment of rRNA Internal Transcribed Spacer 2

Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial

High homogeneity of MMR deficiency in ovarian cancer

Molecular control of endurance training adaptation in male mouse skeletal muscle

Detection and Differentiation of Leishmania spp. in Clinical Specimens by Use of a SYBR Green-Based Real-Time PCR Assay

Integrative Genomic Analyses Reveal an Androgen-Driven Somatic Alteration Landscape in Early-Onset Prostate Cancer

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