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Epithelial-to-Mesenchymal Transition: Epigenetic Reprogramming Driving Cellular Plasticity

Trends in genetics, 2017-12, Vol.33 (12), p.943-959

2017

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Mucins and tumor resistance to chemotherapeutic drugs

Biochimica et biophysica acta, 2014-08, Vol.1846 (1), p.142-151

2014

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The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2

The Journal of experimental medicine, 2016-05, Vol.213 (6), p.897-911

2016

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Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization

Cancer research (Chicago, Ill.), 2020-06, Vol.80 (12), p.2612-2627

2020

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Overexpression of chemokine receptor CXCR2 and ligand CXCL7 in liver metastases from colon cancer is correlated to shorter disease‐free and overall survival

Cancer science, 2015-03, Vol.106 (3), p.262-269

2015

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The oncogenic receptor ErbB2 modulates gemcitabine and irinotecan/SN-38 chemoresistance of human pancreatic cancer cells via hCNT1 transporter and multidrug-resistance associated protein MRP-2

Oncotarget, 2015-05, Vol.6 (13), p.10853-10867

2015

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Mucins and pancreatic cancer

Cancers, 2010-10, Vol.2 (4), p.1794-1812

2010

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The EGF Domains of MUC4 Oncomucin Mediate HER2 Binding Affinity and Promote Pancreatic Cancer Cell Tumorigenesis

Cancers, 2021-11, Vol.13 (22), p.5746

2021

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The mucin MUC4 and its membrane partner ErbB2 regulate biological properties of human CAPAN-2 pancreatic cancer cells via different signalling pathways

PloS one, 2012-02, Vol.7 (2), p.e32232

2012

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TGF-βRII Knock-down in Pancreatic Cancer Cells Promotes Tumor Growth and Gemcitabine Resistance. Importance of STAT3 Phosphorylation on S727

Cancers, 2018-07, Vol.10 (8), p.254

2018

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ZEB2 stably represses RAB25 expression through epigenetic regulation by SIRT1 and DNMTs during epithelial-to-mesenchymal transition

Epigenetics & chromatin, 2018-11, Vol.11 (1), p.70-70, Article 70

2018

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The MUC4 mucin mediates gemcitabine resistance of human pancreatic cancer cells via the Concentrative Nucleoside Transporter family

Oncogene, 2013-03, Vol.32 (13), p.1714-1723

2013

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Abstract P1-05-08: Targeting tumor heterogeneity and breast cancer metastasis through the metastatic microenvironment mediated epigenetic reprogramming

Cancer research (Chicago, Ill.), 2022-02, Vol.82 (4_Supplement), p.P1-P1-05-08

2022

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Colon cancer cells escape 5FU chemotherapy-induced cell death by entering stemness and quiescence associated with the c-Yes/YAP axis

Clinical cancer research, 2014-02, Vol.20 (4), p.837-846

2014

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DNA methyltransferase 3B-mediated intra-tumoral heterogeneity and therapeutic targeting in breast cancer recurrence and metastasis

Molecular cancer research, 2022-11, Vol.20 (11), p.1674-1685

2022

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Tissue Factor Induced by Epithelial-Mesenchymal Transition Triggers a Procoagulant State That Drives Metastasis of Circulating Tumor Cells

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14), p.4270-4282

2016

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DNA Methyltransferase 3B-Mediated Intratumoral Heterogeneity and Therapeutic Targeting in Breast Cancer Recurrence and Metastasis

Molecular cancer research, 2022-11, Vol.20 (11), p.1674-1685

2022

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Abstract LB-147: EMT transcription factors induce tissue factor expression and pro-coagulant properties, supporting early metastasis of circulating tumor cells

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.LB-147-LB-147

2017

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The mucin MUC4 is a transcriptional and post-transcriptional target of K-ras oncogene in pancreatic cancer. Implication of MAPK/AP-1, NF-κB and RalB signaling pathways

Biochimica et biophysica acta, 2015-12, Vol.1849 (12), p.1375-1384

2015

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Abstract 4840: DNA methyltransferase 3B as a mediator in cancer associated inflammation and progression

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.4840-4840

2014

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Abstract B31: The MUC4 oncomucin mediates resistance of human pancreatic cancer cells to FOLFIRINOX drugs

Cancer research (Chicago, Ill.), 2016-12, Vol.76 (24_Supplement), p.B31-B31

2016

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Abstract 2843: DNMT3B mediated DNA methylation and epigenetic reprogramming of metastatic cancer cells

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.2843-2843

2017

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Overexpression of chemokine receptor CXCR 2 and ligand CXCL 7 in liver metastases from colon cancer is correlated to shorter disease‐free and overall survival

Cancer science, 2015-03, Vol.106 (3), p.262-269

2015

Volltextzugriff (PDF)

Colon Cancer Cells Escape 5FU Chemotherapy-Induced Cell Death by Entering Sternness and Quiescence Associated with the c-Yes/YAP Axis

Clinical cancer research, 2014, Vol.20 (4), p.837-846

2014

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Epithelial-to-Mesenchymal Transition: Epigenetic Reprogramming Driving Cellular Plasticity

Mucins and tumor resistance to chemotherapeutic drugs

The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2

Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization

Overexpression of chemokine receptor CXCR2 and ligand CXCL7 in liver metastases from colon cancer is correlated to shorter disease‐free and overall survival

The oncogenic receptor ErbB2 modulates gemcitabine and irinotecan/SN-38 chemoresistance of human pancreatic cancer cells via hCNT1 transporter and multidrug-resistance associated protein MRP-2

Mucins and pancreatic cancer

The EGF Domains of MUC4 Oncomucin Mediate HER2 Binding Affinity and Promote Pancreatic Cancer Cell Tumorigenesis

The mucin MUC4 and its membrane partner ErbB2 regulate biological properties of human CAPAN-2 pancreatic cancer cells via different signalling pathways

TGF-βRII Knock-down in Pancreatic Cancer Cells Promotes Tumor Growth and Gemcitabine Resistance. Importance of STAT3 Phosphorylation on S727

ZEB2 stably represses RAB25 expression through epigenetic regulation by SIRT1 and DNMTs during epithelial-to-mesenchymal transition

The MUC4 mucin mediates gemcitabine resistance of human pancreatic cancer cells via the Concentrative Nucleoside Transporter family

Abstract P1-05-08: Targeting tumor heterogeneity and breast cancer metastasis through the metastatic microenvironment mediated epigenetic reprogramming

Colon cancer cells escape 5FU chemotherapy-induced cell death by entering stemness and quiescence associated with the c-Yes/YAP axis

DNA methyltransferase 3B-mediated intra-tumoral heterogeneity and therapeutic targeting in breast cancer recurrence and metastasis

Tissue Factor Induced by Epithelial-Mesenchymal Transition Triggers a Procoagulant State That Drives Metastasis of Circulating Tumor Cells

DNA Methyltransferase 3B-Mediated Intratumoral Heterogeneity and Therapeutic Targeting in Breast Cancer Recurrence and Metastasis

The EMT Transcription Factor ZEB2 Promotes Proliferation of Primary and Metastatic Melanoma While Suppressing an Invasive, Mesenchymal-Like Phenotype

Abstract LB-147: EMT transcription factors induce tissue factor expression and pro-coagulant properties, supporting early metastasis of circulating tumor cells

The mucin MUC4 is a transcriptional and post-transcriptional target of K-ras oncogene in pancreatic cancer. Implication of MAPK/AP-1, NF-κB and RalB signaling pathways

Abstract 4840: DNA methyltransferase 3B as a mediator in cancer associated inflammation and progression

Abstract B31: The MUC4 oncomucin mediates resistance of human pancreatic cancer cells to FOLFIRINOX drugs

Abstract 2843: DNMT3B mediated DNA methylation and epigenetic reprogramming of metastatic cancer cells

Overexpression of chemokine receptor CXCR 2 and ligand CXCL 7 in liver metastases from colon cancer is correlated to shorter disease‐free and overall survival

Colon Cancer Cells Escape 5FU Chemotherapy-Induced Cell Death by Entering Sternness and Quiescence Associated with the c-Yes/YAP Axis

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