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NAD+ and vitamin B3: from metabolism to therapies

The Journal of pharmacology and experimental therapeutics, 2008-03, Vol.324 (3), p.883

Sauve, Anthony A

2008

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NAD+-Dependent Activation of Sirt1 Corrects the Phenotype in a Mouse Model of Mitochondrial Disease

Cell metabolism, 2014-06, Vol.19 (6), p.1042-1049

2014

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Lethal Cardiomyopathy in Mice Lacking Transferrin Receptor in the Heart

Cell reports (Cambridge), 2015-10, Vol.13 (3), p.533-545

2015

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PARP-1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation

Cell metabolism, 2011-04, Vol.13 (4), p.461-468

2011

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Pharmacological Inhibition of Poly(ADP-Ribose) Polymerases Improves Fitness and Mitochondrial Function in Skeletal Muscle

Cell metabolism, 2014-06, Vol.19 (6), p.1034-1041

2014

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Nutrient-Sensitive Mitochondrial NAD + Levels Dictate Cell Survival

Cell, 2007-09, Vol.130 (6), p.1095-1107

2007

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The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity

Cell metabolism, 2012-06, Vol.15 (6), p.838-847

2012

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Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice

Hepatology (Baltimore, Md.), 2016-04, Vol.63 (4), p.1190-1204

2016

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Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity

Nature (London), 2014-04, Vol.508 (7495), p.258-262

2014

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SIRT2 induces the checkpoint kinase BubR1 to increase lifespan

The EMBO journal, 2014-07, Vol.33 (13), p.1438-1453

2014

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Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt

Developmental cell, 2008-05, Vol.14 (5), p.661-673

2008

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NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation

Science translational medicine, 2016-10, Vol.8 (361), p.361ra139

2016

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Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects

The Journal of clinical investigation, 2015-12, Vol.125 (12), p.4592-4600

2015

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The biochemistry of sirtuins

Annual review of biochemistry, 2006-01, Vol.75 (1), p.435-465

2006

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PARP-2 Regulates SIRT1 Expression and Whole-Body Energy Expenditure

Cell metabolism, 2011-04, Vol.13 (4), p.450-460

2011

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Triple-Isotope Tracing for Pathway Discernment of NMN-Induced NAD + Biosynthesis in Whole Mice

International journal of molecular sciences, 2023-07, Vol.24 (13), p.11114

2023

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Metabolic Disease, NAD Metabolism, Nicotinamide Riboside, and the Gut Microbiome: Connecting the Dots from the Gut to Physiology

mSystems, 2022-02, Vol.7 (1), p.e0122321-e0122321

Sauve, Anthony A

2022

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SIRT4 Represses Peroxisome Proliferator-Activated Receptor α Activity To Suppress Hepatic Fat Oxidation

Molecular and Cellular Biology, 2013-11, Vol.33 (22), p.4552-4561

2013

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Neuronal SIRT1 Activation as a Novel Mechanism Underlying the Prevention of Alzheimer Disease Amyloid Neuropathology by Calorie Restriction

The Journal of biological chemistry, 2006-08, Vol.281 (31), p.21745-21754

2006

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Dual mode action of mangiferin in mouse liver under high fat diet

PloS one, 2014-03, Vol.9 (3), p.e90137-e90137

2014

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Enzymes in the NAD+ Salvage Pathway Regulate SIRT1 Activity at Target Gene Promoters

The Journal of biological chemistry, 2009-07, Vol.284 (30), p.20408-20417

2009

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Mangiferin stimulates carbohydrate oxidation and protects against metabolic disorders induced by high-fat diets

Diabetes (New York, N.Y.), 2014-11, Vol.63 (11), p.3626-3636

2014

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Sir2 Regulation by Nicotinamide Results from Switching between Base Exchange and Deacetylation Chemistry

Biochemistry (Easton), 2003-08, Vol.42 (31), p.9249-9256

2003

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Global Analysis of Transcriptional Regulation by Poly(ADP-ribose) Polymerase-1 and Poly(ADP-ribose) Glycohydrolase in MCF-7 Human Breast Cancer Cells

The Journal of biological chemistry, 2009-12, Vol.284 (49), p.33926-33938

2009

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Dihydronicotinamide riboside is a potent NAD+ concentration enhancer in vitro and in vivo

The Journal of biological chemistry, 2019-06, Vol.294 (23), p.9295-9307

2019

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NAD+ and vitamin B3: from metabolism to therapies

NAD+-Dependent Activation of Sirt1 Corrects the Phenotype in a Mouse Model of Mitochondrial Disease

Lethal Cardiomyopathy in Mice Lacking Transferrin Receptor in the Heart

PARP-1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation

Pharmacological Inhibition of Poly(ADP-Ribose) Polymerases Improves Fitness and Mitochondrial Function in Skeletal Muscle

Nutrient-Sensitive Mitochondrial NAD + Levels Dictate Cell Survival

The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity

Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice

Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity

SIRT2 induces the checkpoint kinase BubR1 to increase lifespan

Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt

NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation

Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects

The biochemistry of sirtuins

PARP-2 Regulates SIRT1 Expression and Whole-Body Energy Expenditure

Triple-Isotope Tracing for Pathway Discernment of NMN-Induced NAD + Biosynthesis in Whole Mice

Metabolic Disease, NAD Metabolism, Nicotinamide Riboside, and the Gut Microbiome: Connecting the Dots from the Gut to Physiology

SIRT4 Represses Peroxisome Proliferator-Activated Receptor α Activity To Suppress Hepatic Fat Oxidation

Neuronal SIRT1 Activation as a Novel Mechanism Underlying the Prevention of Alzheimer Disease Amyloid Neuropathology by Calorie Restriction

Dual mode action of mangiferin in mouse liver under high fat diet

Enzymes in the NAD+ Salvage Pathway Regulate SIRT1 Activity at Target Gene Promoters

Mangiferin stimulates carbohydrate oxidation and protects against metabolic disorders induced by high-fat diets

Sir2 Regulation by Nicotinamide Results from Switching between Base Exchange and Deacetylation Chemistry

Global Analysis of Transcriptional Regulation by Poly(ADP-ribose) Polymerase-1 and Poly(ADP-ribose) Glycohydrolase in MCF-7 Human Breast Cancer Cells

Dihydronicotinamide riboside is a potent NAD+ concentration enhancer in vitro and in vivo

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