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Chemical probing for examining the structure of modified RNAs and ligand binding to RNA

Methods (San Diego, Calif.), 2019-03, Vol.156, p.110-120

2019

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Post-transcriptional Modifications Modulate rRNA Structure and Ligand Interactions

Accounts of chemical research, 2016-05, Vol.49 (5), p.893-901

2016

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Calculated pKa Values for a Series of Aza- and Deaza-Modified Nucleobases

The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory, 2023-04, Vol.127 (15), p.3526-3534

2023

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Calculated p K a Values for a Series of Aza- and Deaza-Modified Nucleobases

The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory, 2023-04, Vol.127 (15), p.3526-3534

2023

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Amino acid-linked platinum(II) analogues have altered specificity for RNA compared to cisplatin

Chemical communications (Cambridge, England), 2014-04, Vol.50 (30), p.3918-3920

2014

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Calculations of pKa Values for a Series of Naturally Occurring Modified Nucleobases

The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory, 2022-03, Vol.126 (9), p.1518-1529

2022

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Use of a fluorescence assay to determine relative affinities of semisynthetic aminoglycosides to small RNAs representing bacterial and mitochondrial A sites

Bioorganic & medicinal chemistry, 2019-11, Vol.27 (22), p.115121-115121, Article 115121

2019

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Pseudouridine modifications influence binding of aminoglycosides to helix 69 of bacterial ribosomes

Organic & biomolecular chemistry, 2017-10, Vol.15 (40), p.8535-8543

2017

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Type-specific cell line models for type-specific ovarian cancer research

PloS one, 2013-09, Vol.8 (9), p.e72162-e72162

2013

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Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type

The Journal of pathology, 2016-02, Vol.238 (3), p.389-400

2016

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Design, Multigram Synthesis, and in Vitro and in Vivo Evaluation of Propylamycin: A Semisynthetic 4,5-Deoxystreptamine Class Aminoglycoside for the Treatment of Drug-Resistant Enterobacteriaceae and Other Gram-Negative Pathogens

Journal of the American Chemical Society, 2019-03, Vol.141 (12), p.5051-5061

2019

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A modified fluorescent intercalator displacement assay for RNA ligand discovery

Analytical biochemistry, 2011-01, Vol.408 (2), p.269-276

2011

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Cisplatin Targeting of Bacterial Ribosomal RNA Hairpins

International journal of molecular sciences, 2015-09, Vol.16 (9), p.21392-21409

2015

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Calculations of p K a Values for a Series of Naturally Occurring Modified Nucleobases

The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory, 2022-03, Vol.126 (9), p.1518-1529

2022

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Increasing faculty support, respect, and ability to help doctoral students explore non-academic research career opportunities

Heliyon, 2023-01, Vol.9 (1), p.e13052-e13052, Article e13052

2023

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Exposure to multiple career pathways by biomedical doctoral students at a public research university

PloS one, 2018-06, Vol.13 (6), p.e0199720-e0199720

2018

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Loss of BAF250a (ARID1A) is frequent in high-grade endometrial carcinomas

The Journal of pathology, 2011-07, Vol.224 (3), p.328-333

2011

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The development of peptide ligands that target helix 69 rRNA of bacterial ribosomes

Bioorganic & medicinal chemistry, 2016-09, Vol.24 (18), p.4486-4491

2016

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A new role for cisplatin: probing ribosomal RNA structure

Chemical communications (Cambridge, England), 2009-01 (1), p.107-109

2009

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FOXL2 is a sensitive and specific marker for sex cord-stromal tumors of the ovary

The American journal of surgical pathology, 2011-04, Vol.35 (4), p.484-494

2011

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Probing Conformational States of Modified Helix 69 in 50S Ribosomes

Journal of the American Chemical Society, 2011-06, Vol.133 (22), p.8396-8399

2011

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Production of Nanostructures of DNA on Surfaces

Nano letters, 2002-08, Vol.2 (8), p.863-867

2002

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An Advanced Apralog with Increased in vitro and in vivo Activity toward Gram‐negative Pathogens and Reduced ex vivo Cochleotoxicity

ChemMedChem, 2021-01, Vol.16 (2), p.335-339

2021

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Structure modulation of helix 69 from Escherichia coli 23S ribosomal RNA by pseudouridylations

Nucleic acids research, 2014-04, Vol.42 (6), p.3971-3981

2014

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Chemical probing for examining the structure of modified RNAs and ligand binding to RNA

Post-transcriptional Modifications Modulate rRNA Structure and Ligand Interactions

Calculated pKa Values for a Series of Aza- and Deaza-Modified Nucleobases

Calculated p K a Values for a Series of Aza- and Deaza-Modified Nucleobases

Amino acid-linked platinum(II) analogues have altered specificity for RNA compared to cisplatin

Calculations of pKa Values for a Series of Naturally Occurring Modified Nucleobases

Use of a fluorescence assay to determine relative affinities of semisynthetic aminoglycosides to small RNAs representing bacterial and mitochondrial A sites

Pseudouridine modifications influence binding of aminoglycosides to helix 69 of bacterial ribosomes

Type-specific cell line models for type-specific ovarian cancer research

Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type

Design, Multigram Synthesis, and in Vitro and in Vivo Evaluation of Propylamycin: A Semisynthetic 4,5-Deoxystreptamine Class Aminoglycoside for the Treatment of Drug-Resistant Enterobacteriaceae and Other Gram-Negative Pathogens

A modified fluorescent intercalator displacement assay for RNA ligand discovery

A cross-institutional analysis of the effects of broadening trainee professional development on research productivity

Cisplatin Targeting of Bacterial Ribosomal RNA Hairpins

Calculations of p K a Values for a Series of Naturally Occurring Modified Nucleobases

Increasing faculty support, respect, and ability to help doctoral students explore non-academic research career opportunities

Exposure to multiple career pathways by biomedical doctoral students at a public research university

Loss of BAF250a (ARID1A) is frequent in high-grade endometrial carcinomas

The development of peptide ligands that target helix 69 rRNA of bacterial ribosomes

A new role for cisplatin: probing ribosomal RNA structure

FOXL2 is a sensitive and specific marker for sex cord-stromal tumors of the ovary

Probing Conformational States of Modified Helix 69 in 50S Ribosomes

Production of Nanostructures of DNA on Surfaces

An Advanced Apralog with Increased in vitro and in vivo Activity toward Gram‐negative Pathogens and Reduced ex vivo Cochleotoxicity

Structure modulation of helix 69 from Escherichia coli 23S ribosomal RNA by pseudouridylations

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