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Endothelial NADPH oxidases: which NOX to target in vascular disease?

Trends in endocrinology and metabolism, 2014-09, Vol.25 (9), p.452-463

2014

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Reactive Oxygen Species Can Provide Atheroprotection via NOX4-Dependent Inhibition of Inflammation and Vascular Remodeling

Arteriosclerosis, thrombosis, and vascular biology, 2016-02, Vol.36 (2), p.295-307

2016

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NADPH oxidases in traumatic brain injury – Promising therapeutic targets?

Redox biology, 2018-06, Vol.16, p.285-293

2018

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Differential contribution of Nox1, Nox2 and Nox4 to kidney vascular oxidative stress and endothelial dysfunction in obesity

Redox biology, 2020-01, Vol.28, p.101330, Article 101330

2020

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ROS-induced ROS release orchestrated by Nox4, Nox2, and mitochondria in VEGF signaling and angiogenesis

American Journal of Physiology: Cell Physiology, 2017-06, Vol.312 (6), p.C749-C764

2017

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Nox4: A Hydrogen Peroxide-Generating Oxygen Sensor

Biochemistry (Easton), 2014-08, Vol.53 (31), p.5111-5120

2014

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Coordination between NADPH oxidase and vascular peroxidase 1 promotes dysfunctions of endothelial progenitor cells in hypoxia-induced pulmonary hypertensive rats

European journal of pharmacology, 2019-08, Vol.857, p.172459-172459, Article 172459

2019

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NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury

Brain (London, England : 1878), 2012-03, Vol.135 (Pt 3), p.886-899

2012

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Magnesium isoglycyrrhizinate alleviates fructose-induced liver oxidative stress and inflammatory injury through suppressing NOXs

European journal of pharmacology, 2020-09, Vol.883, p.173314-173314, Article 173314

2020

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Differential Roles of the NADPH-Oxidase 1 and 2 in Platelet Activation and Thrombosis

Arteriosclerosis, thrombosis, and vascular biology, 2016-05, Vol.36 (5), p.846-854

2016

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Therapeutic potential of NADPH oxidase 1/4 inhibitors

British journal of pharmacology, 2017-06, Vol.174 (12), p.1647-1669

2017

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Regulation of Nox and Duox enzymatic activity and expression

Free radical biology & medicine, 2007-08, Vol.43 (3), p.319-331

2007

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Hypoxia-Dependent Regulation of Nonphagocytic NADPH Oxidase Subunit NOX4 in the Pulmonary Vasculature

Circulation research, 2007-08, Vol.101 (3), p.258-267

2007

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New insights in the molecular regulation of the NADPH oxidase 2 activity: Negative modulation by Poldip2

Free radical biology & medicine, 2023-04, Vol.199, p.113-125

2023

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Oxidative stress, Noxs, and hypertension: Experimental evidence and clinical controversies

Annals of medicine (Helsinki), 2012-06, Vol.44 (S1), p.S2-S16

2012

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Structural basis for EROS binding to human phagocyte NADPH oxidase NOX2

Proceedings of the National Academy of Sciences - PNAS, 2024-06, Vol.121 (23), p.e2320388121

2024

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Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons

Nature cell biology, 2018-03, Vol.20 (3), p.307-319

2018

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CRISPR-gene-engineered CYBB knock-out PLB-985 cells, a useful model to study functional impact of X-linked chronic granulomatous disease mutations: application to the G412E X91+-CGD mutation

Clinical and experimental immunology, 2023-04, Vol.212 (2), p.156-165

2023

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Reactive oxygen species-induced activation of ERK and p38 MAPK mediates PMA-induced NETs release from human neutrophils

Journal of cellular biochemistry, 2013-03, Vol.114 (3), p.532-540

2013

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Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

Nature reviews. Drug discovery, 2011-06, Vol.10 (6), p.453-471

2011

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Topically Administered NOX4 Inhibitor, GLX7013114, Is Efficacious in Treating the Early Pathological Events of Diabetic Retinopathy

Diabetes (New York, N.Y.), 2023-05, Vol.72 (5), p.638-652

2023

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LPS-induced renal inflammation is prevented by (−)‐epicatechin in rats

Redox biology, 2017-04, Vol.11, p.342-349

2017

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NADPH oxidases as drug targets and biomarkers in neurodegenerative diseases: What is the evidence?

Free radical biology & medicine, 2017-11, Vol.112, p.387-396

2017

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ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence

Oncogene, 2012-03, Vol.31 (9), p.1117-1129

2012

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NADPH Oxidase 4 (NOX4) in Cancer: Linking Redox Signals to Oncogenic Metabolic Adaptation

International journal of molecular sciences, 2022-02, Vol.23 (5), p.2702

Szanto, Ildiko

2022

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Endothelial NADPH oxidases: which NOX to target in vascular disease?

Reactive Oxygen Species Can Provide Atheroprotection via NOX4-Dependent Inhibition of Inflammation and Vascular Remodeling

NADPH oxidases in traumatic brain injury – Promising therapeutic targets?

Differential contribution of Nox1, Nox2 and Nox4 to kidney vascular oxidative stress and endothelial dysfunction in obesity

ROS-induced ROS release orchestrated by Nox4, Nox2, and mitochondria in VEGF signaling and angiogenesis

Nox4: A Hydrogen Peroxide-Generating Oxygen Sensor

Coordination between NADPH oxidase and vascular peroxidase 1 promotes dysfunctions of endothelial progenitor cells in hypoxia-induced pulmonary hypertensive rats

NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury

Magnesium isoglycyrrhizinate alleviates fructose-induced liver oxidative stress and inflammatory injury through suppressing NOXs

Differential Roles of the NADPH-Oxidase 1 and 2 in Platelet Activation and Thrombosis

Therapeutic potential of NADPH oxidase 1/4 inhibitors

Regulation of Nox and Duox enzymatic activity and expression

Hypoxia-Dependent Regulation of Nonphagocytic NADPH Oxidase Subunit NOX4 in the Pulmonary Vasculature

New insights in the molecular regulation of the NADPH oxidase 2 activity: Negative modulation by Poldip2

Oxidative stress, Noxs, and hypertension: Experimental evidence and clinical controversies

Structural basis for EROS binding to human phagocyte NADPH oxidase NOX2

Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons

CRISPR-gene-engineered CYBB knock-out PLB-985 cells, a useful model to study functional impact of X-linked chronic granulomatous disease mutations: application to the G412E X91+-CGD mutation

Reactive oxygen species-induced activation of ERK and p38 MAPK mediates PMA-induced NETs release from human neutrophils

Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

Topically Administered NOX4 Inhibitor, GLX7013114, Is Efficacious in Treating the Early Pathological Events of Diabetic Retinopathy

LPS-induced renal inflammation is prevented by (−)‐epicatechin in rats

NADPH oxidases as drug targets and biomarkers in neurodegenerative diseases: What is the evidence?

ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence

NADPH Oxidase 4 (NOX4) in Cancer: Linking Redox Signals to Oncogenic Metabolic Adaptation

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