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Discovery of a potent inhibitor of chaperone-mediated autophagy that targets the HSC70-LAMP2A interaction in non-small cell lung cancer cells

British journal of pharmacology, 2023-07

2023

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The Simultaneous Effects of Aerobic Training and Octopamine on the Mitophagy of the Brown Adipose Tissue after the Induction of Intoxication by Deeply Heated Oil in Male Wistar Rats

Journal of fasting and health, 2020-09, Vol.8 (3), p.151-158

2020

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VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for α-Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease

The Journal of neuroscience, 2015-07, Vol.35 (29), p.10613-10628

2015

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Regulation of self-renewal in ovarian cancer stem cells by fructose via chaperone-mediated autophagy

Biochimica et biophysica acta. Molecular basis of disease, 2023-08, Vol.1869 (6), p.166723-166723, Article 166723

2023

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Increased LAMP2A levels correlate with a shorter disease-free survival of HER2 negative breast cancer patients and increased breast cancer cell viability

Biochemical and biophysical research communications, 2021-09, Vol.569, p.47-53

2021

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Inhibition of tumor suppressor p73 by nerve growth factor receptor via chaperone-mediated autophagy

Journal of molecular cell biology, 2020-09, Vol.12 (9), p.700-712

2020

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Chaperone-Mediated Autophagy in the Light of Evolution: Insight from Fish

Molecular biology and evolution, 2020-10, Vol.37 (10), p.2887-2899

2020

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HIV-1 Tat alters neuronal autophagy by modulating autophagosome fusion to the lysosome: implications for HIV-associated neurocognitive disorders

The Journal of neuroscience, 2015-02, Vol.35 (5), p.1921-1938

2015

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DJ-1 Inhibits α-Synuclein Aggregation by Regulating Chaperone-Mediated Autophagy

Frontiers in aging neuroscience, 2017-09, Vol.9, p.308-308

2017

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Site‐specific photo‐crosslinking/cleavage for protein–protein interface identification reveals oligomeric assembly of lysosomal‐associated membrane protein type 2A in mammalian cells

Protein science, 2023-12, Vol.32 (12), p.e4823-n/a

2023

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Chaperone mediated autophagy in aging: Starve to prosper

Ageing research reviews, 2016-12, Vol.32, p.13-21

2016

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APOE4 dysregulates autophagy in cultured cells

Autophagy reports, 2022-01, Vol.1 (1), p.29-33

2022

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Lysosomal membrane protein TMEM106B modulates hematopoietic stem and progenitor cell proliferation and differentiation by regulating LAMP2A stability

The FASEB journal, 2024-08, Vol.38 (15), p.e23870-n/a

2024

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Chaperone-mediated autophagy in neurodegenerative diseases: mechanisms and therapy

Molecular and cellular biochemistry, 2023-10, Vol.478 (10), p.2173-2190

2023

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Chaperone-Mediated Autophagy: A Potential Target for Metabolic Diseases

Current medicinal chemistry, 2023-01, Vol.30 (16), p.1887-1899

2023

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Chaperone-Mediated Autophagy Regulates Hypoxic Pathology in Cardiomyocytes

Autophagy reports, 2023-12, Vol.2 (1)

2023

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Boosting chaperone-mediated autophagy in vivo mitigates α-synuclein-induced neurodegeneration

Brain (London, England : 1878), 2013-07, Vol.136 (Pt 7), p.2130-2146

2013

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Geniposide reduces α-synuclein by blocking microRNA-21/lysosome-associated membrane protein 2A interaction in Parkinson disease models

Brain research, 2016-08, Vol.1644, p.98-106

2016

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Autophagy and LRRK2 in the Aging Brain

Frontiers in neuroscience, 2019-12, Vol.13, p.1352-1352

2019

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Chaperone‐mediated autophagy protects the bone formation from excessive inflammation through PI3K/AKT/GSK3β/β‐catenin pathway

The FASEB journal, 2024-05, Vol.38 (10), p.e23646-n/a

2024

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Identification of a novel aromatic-turmerone analog that activates chaperone-mediated autophagy through the persistent activation of p38

Frontiers in cell and developmental biology, 2024-08, Vol.12, p.1418296

2024

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Milk Fat Globule-EGF Factor 8 Alleviates Pancreatic Fibrosis by Inhibiting ER Stress-Induced Chaperone-Mediated Autophagy in Mice

Frontiers in pharmacology, 2021-08, Vol.12, p.707259-707259

2021

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The two-domain architecture of LAMP2A within the lysosomal lumen regulates its interaction with HSPA8/Hsc70

Autophagy reports, 2022-12, Vol.1 (1), p.205-209

2022

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Chaperone-Mediated Autophagy after Spinal Cord Injury

Journal of neurotrauma, 2020-08, Vol.37 (15), p.1687-1695

2020

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LAMP2A regulates the balance of mesenchymal stem cell adipo-osteogenesis via the Wnt/β-catenin/GSK3β signaling pathway

Journal of molecular medicine (Berlin, Germany), 2023-07, Vol.101 (7), p.783-799

2023

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Discovery of a potent inhibitor of chaperone-mediated autophagy that targets the HSC70-LAMP2A interaction in non-small cell lung cancer cells

The Simultaneous Effects of Aerobic Training and Octopamine on the Mitophagy of the Brown Adipose Tissue after the Induction of Intoxication by Deeply Heated Oil in Male Wistar Rats

VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for α-Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease

Regulation of self-renewal in ovarian cancer stem cells by fructose via chaperone-mediated autophagy

Increased LAMP2A levels correlate with a shorter disease-free survival of HER2 negative breast cancer patients and increased breast cancer cell viability

Inhibition of tumor suppressor p73 by nerve growth factor receptor via chaperone-mediated autophagy

Chaperone-Mediated Autophagy in the Light of Evolution: Insight from Fish

HIV-1 Tat alters neuronal autophagy by modulating autophagosome fusion to the lysosome: implications for HIV-associated neurocognitive disorders

DJ-1 Inhibits α-Synuclein Aggregation by Regulating Chaperone-Mediated Autophagy

Site‐specific photo‐crosslinking/cleavage for protein–protein interface identification reveals oligomeric assembly of lysosomal‐associated membrane protein type 2A in mammalian cells

Chaperone mediated autophagy in aging: Starve to prosper

APOE4 dysregulates autophagy in cultured cells

Lysosomal membrane protein TMEM106B modulates hematopoietic stem and progenitor cell proliferation and differentiation by regulating LAMP2A stability

Chaperone-mediated autophagy in neurodegenerative diseases: mechanisms and therapy

Chaperone-Mediated Autophagy: A Potential Target for Metabolic Diseases

Chaperone-Mediated Autophagy Regulates Hypoxic Pathology in Cardiomyocytes

Boosting chaperone-mediated autophagy in vivo mitigates α-synuclein-induced neurodegeneration

Geniposide reduces α-synuclein by blocking microRNA-21/lysosome-associated membrane protein 2A interaction in Parkinson disease models

Autophagy and LRRK2 in the Aging Brain

Chaperone‐mediated autophagy protects the bone formation from excessive inflammation through PI3K/AKT/GSK3β/β‐catenin pathway

Identification of a novel aromatic-turmerone analog that activates chaperone-mediated autophagy through the persistent activation of p38

Milk Fat Globule-EGF Factor 8 Alleviates Pancreatic Fibrosis by Inhibiting ER Stress-Induced Chaperone-Mediated Autophagy in Mice

The two-domain architecture of LAMP2A within the lysosomal lumen regulates its interaction with HSPA8/Hsc70

Chaperone-Mediated Autophagy after Spinal Cord Injury

LAMP2A regulates the balance of mesenchymal stem cell adipo-osteogenesis via the Wnt/β-catenin/GSK3β signaling pathway

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