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Inhibitors of the Candida albicans Major Facilitator Superfamily Transporter Mdr1p Responsible for Fluconazole Resistance

PloS one, 2015-05, Vol.10 (5), p.e0126350

2015

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Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer

Proceedings of the National Academy of Sciences - PNAS, 2014-03, Vol.111 (10), p.3865-3870

2014

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Efflux-Mediated Antifungal Drug Resistance

Clinical Microbiology Reviews, 2009-04, Vol.22 (2), p.291-321

2009

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Structural and Functional Elucidation of Yeast Lanosterol 14α-Demethylase in Complex with Agrochemical Antifungals

PloS one, 2016-12, Vol.11 (12), p.e0167485-e0167485

2016

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Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases

Journal of fungi (Basel), 2021-01, Vol.7 (2), p.67

2021

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Exploring Cryptococcus neoformans CYP51 and Its Cognate Reductase as a Drug Target

Journal of fungi (Basel), 2022-11, Vol.8 (12), p.1256

2022

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Functional Expression of Recombinant Candida auris Proteins in Saccharomyces cerevisiae Enables Azole Susceptibility Evaluation and Drug Discovery

Journal of fungi (Basel), 2023-01, Vol.9 (2), p.168

2023

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Correction: Monk, B.C.; Keniya, M.V. Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases. J. Fungi 2021, 7 , 67

Journal of fungi (Basel), 2021-11, Vol.7 (12), p.1011

2021

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Characterisation of Candida parapsilosis CYP51 as a Drug Target Using Saccharomyces cerevisiae as Host

Journal of fungi (Basel), 2022-01, Vol.8 (1), p.69

2022

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Clorgyline Analogs Synergize with Azoles against Drug Efflux in Candida auris

Journal of fungi (Basel), 2023-06, Vol.9 (6), p.663

2023

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Fungal Lanosterol 14α-demethylase: A target for next-generation antifungal design

Biochimica et biophysica acta. Proteins and proteomics, 2020-03, Vol.1868 (3), p.140206, Article 140206

2020

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Structural Insights into the Azole Resistance of the Candida albicans Darlington Strain Using Saccharomyces cerevisiae Lanosterol 14α-Demethylase as a Surrogate

Journal of fungi (Basel), 2021-10, Vol.7 (11), p.897

2021

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Drug Resistance Is Conferred on the Model Yeast Saccharomyces cerevisiae by Expression of Full-Length Melanoma-Associated Human ATP-Binding Cassette Transporter ABCB5

Molecular pharmaceutics, 2014-10, Vol.11 (10), p.3452-3462

2014

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Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14α-demethylase

Scientific reports, 2016-05, Vol.6 (1), p.26213-26213, Article 26213

2016

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Evolutionary dynamics in gut-colonizing Candida glabrata during caspofungin therapy: Emergence of clinically important mutations in sphingolipid biosynthesis

PLoS pathogens, 2024-09, Vol.20 (9), p.e1012521

2024

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Attenuated apoptotic BAX expression as a xenobiotic reporter in Saccharomyces cerevisiae

FEMS yeast research, 2019-08, Vol.19 (5), p.1

2019

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Targeting efflux pumps to overcome antifungal drug resistance

Future medicinal chemistry, 2016-08, Vol.8 (12), p.1485-1501

2016

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Heterologous expression of Candida albicans Pma1p in Saccharomyces cerevisiae

FEMS yeast research, 2013-05, Vol.13 (3), p.302-311

2013

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Functional Expression of Recombinant ICandida auris/I Proteins in ISaccharomyces cerevisiae/I Enables Azole Susceptibility Evaluation and Drug Discovery

Journal of fungi (Basel), 2023-01, Vol.9 (2)

2023

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Exploring ICryptococcus neoformans/I CYP51 and Its Cognate Reductase as a Drug Target

Journal of fungi (Basel), 2022-11, Vol.8 (12)

2022

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Clorgyline Analogs Synergize with Azoles against Drug Efflux in ICandida auris/I

Journal of fungi (Basel), 2023-06, Vol.9 (6)

2023

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Structural and Functional Elucidation of Yeast Lanosterol 14[alpha]-Demethylase in Complex with Agrochemical Antifungals

PloS one, 2016-12, Vol.11 (12), p.e0167485

2016

Volltextzugriff (PDF)

Heterologous expression of C andida albicans Pma1p in S accharomyces cerevisiae

FEMS yeast research, 2013-05, Vol.13 (3), p.302-311

2013

Volltextzugriff (PDF)

Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14[alpha]-demethylase

Scientific reports, 2016-05, Vol.6, p.26213

2016

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Inhibitors of the Candida albicans Major Facilitator Superfamily Transporter Mdr1p Responsible for Fluconazole Resistance: e0126350

PloS one, 2015-05, Vol.10 (5)

2015

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Inhibitors of the Candida albicans Major Facilitator Superfamily Transporter Mdr1p Responsible for Fluconazole Resistance

Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer

Efflux-Mediated Antifungal Drug Resistance

Structural and Functional Elucidation of Yeast Lanosterol 14α-Demethylase in Complex with Agrochemical Antifungals

Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases

Exploring Cryptococcus neoformans CYP51 and Its Cognate Reductase as a Drug Target

Functional Expression of Recombinant Candida auris Proteins in Saccharomyces cerevisiae Enables Azole Susceptibility Evaluation and Drug Discovery

Correction: Monk, B.C.; Keniya, M.V. Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases. J. Fungi 2021, 7 , 67

Characterisation of Candida parapsilosis CYP51 as a Drug Target Using Saccharomyces cerevisiae as Host

Clorgyline Analogs Synergize with Azoles against Drug Efflux in Candida auris

Fungal Lanosterol 14α-demethylase: A target for next-generation antifungal design

Structural Insights into the Azole Resistance of the Candida albicans Darlington Strain Using Saccharomyces cerevisiae Lanosterol 14α-Demethylase as a Surrogate

Drug Resistance Is Conferred on the Model Yeast Saccharomyces cerevisiae by Expression of Full-Length Melanoma-Associated Human ATP-Binding Cassette Transporter ABCB5

Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14α-demethylase

Evolutionary dynamics in gut-colonizing Candida glabrata during caspofungin therapy: Emergence of clinically important mutations in sphingolipid biosynthesis

Attenuated apoptotic BAX expression as a xenobiotic reporter in Saccharomyces cerevisiae

Targeting efflux pumps to overcome antifungal drug resistance

Heterologous expression of Candida albicans Pma1p in Saccharomyces cerevisiae

Functional Expression of Recombinant ICandida auris/I Proteins in ISaccharomyces cerevisiae/I Enables Azole Susceptibility Evaluation and Drug Discovery

Exploring ICryptococcus neoformans/I CYP51 and Its Cognate Reductase as a Drug Target

Clorgyline Analogs Synergize with Azoles against Drug Efflux in ICandida auris/I

Structural and Functional Elucidation of Yeast Lanosterol 14[alpha]-Demethylase in Complex with Agrochemical Antifungals

Heterologous expression of C andida albicans Pma1p in S accharomyces cerevisiae

Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14[alpha]-demethylase

Inhibitors of the Candida albicans Major Facilitator Superfamily Transporter Mdr1p Responsible for Fluconazole Resistance: e0126350

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