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Novel 3-(pyrazol-4-yl)-2-(1H-indole-3-carbonyl)acrylonitrile derivatives induce intrinsic and extrinsic apoptotic death mediated P53 in HCT116 colon carcinoma

Scientific reports, 2023-12, Vol.13 (1), p.22486-22486, Article 22486

2023

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Yttrium Oxide nanoparticles induce cytotoxicity, genotoxicity, apoptosis, and ferroptosis in the human triple-negative breast cancer MDA-MB-231 cells

BMC cancer, 2023-11, Vol.23 (1), p.1-1151, Article 1151

2023

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Synthesis of novel acridines, tetrahydrodipyrazolo [3,4-b:4',3'-e]pyridines, tri-substituted methanes (TRSMs) bearing 2-(4-(1-phenyl-1H-pyrazol-3-yl)phenoxy)-N-phenylacetamide unit as novel hybrid molecules

Synthetic communications, 2023-05, Vol.53 (10), p.696-707

2023

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DNA Fragmentation, Cell Cycle Arrest, and Docking Study of Novel Bis Spiro-cyclic 2-oxindole of Pyrimido[4,5-b]quinoline-4,6-dione Derivatives Against Breast Carcinoma

Current cancer drug targets, 2018-05, Vol.18 (4), p.372-381

2018

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Synthetic Routes to Spirocyclic Pyridazines, Partially-Saturated Pyridazines and Their Condensed Derivatives

Current organic chemistry, 2016-06, Vol.20 (14), p.1512-1546

2016

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Novel Tetrahydro-[1,2,4]triazolo[3,4- a ]isoquinoline Chalcones Suppress Breast Carcinoma through Cell Cycle Arrests and Apoptosis

Molecules (Basel, Switzerland), 2023-04, Vol.28 (8), p.3338

2023

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An overview on synthetic strategies for the construction of star-shaped molecules

RSC advances, 2019-05, Vol.9 (29), p.1666-16682

2019

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Multicomponent Synthesis of Novel bis(2-amino-tetrahydro-4H-chromene-3- carbonitrile) Derivatives Linked to Arene or Heteroarene Cores

Current organic synthesis, 2016-08, Vol.13 (4), p.601-610

2016

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Synthesis, Cytotoxicity and Molecular Docking Simulation of Novel bis-1,4-Dihydropyridines Linked to Aliphatic or Arene Core via Amide or Ester-Amide Linkages

Mini reviews in medicinal chemistry, 2020-01, Vol.20 (9), p.801-816

2020

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Novel thiazole-based cyanoacrylamide derivatives: DNA cleavage, DNA/BSA binding properties and their anticancer behaviour against colon and breast cancer cells

BMC chemistry, 2024-09, Vol.18 (1), p.183-17, Article 183

2024

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Microwave Assisted Multi-Component Synthesis of Novel Bis(1,4-dihydropyridines) Based Arenes or Heteroarenes

Heterocycles, 2016-05, Vol.92 (5), p.910

2016

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Novel Scaffolds Based on Bis-thiazole Connected to Quinoxaline or Thienothiophene through 2-Phenoxy- N -arylacetamide Groups as New Hybrid Molecules: Synthesis, Antibacterial Activity, and Molecular Docking Investigations

ACS omega, 2023-11, Vol.8 (46), p.44312-44327

2023

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Utility of 2‑Chloro‑N‑arylacetamide and 1,1′-(Piperazine-1,4-diyl)bis(2-chloroethanone) as Versatile Precursors for Novel Mono- and Bis[thienopyridines]

ACS omega, 2024-03, Vol.9 (9), p.10146-10159

2024

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Biological Activities and Docking Studies on Novel Bis 1,4-DHPS Linked to Arene Core via Ether or Ester Linkage

Letters in drug design & discovery, 2018-01, Vol.15 (10), p.1036-1045

2018

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Novel hybrid thiazoles, bis-thiazoles linked to azo-sulfamethoxazole: Synthesis, docking, and antimicrobial activity

Heliyon, 2024-05, Vol.10 (10), p.e31082-e31082, Article e31082

2024

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New Azacycles by One‐Pot Three‐Component Hantzsch‐Like Synthesis of Tetra(hexa)azacyclopenta[a]anthracenes, Tetraazaindeno[5,4‐b]fluorenes, and Oxatetraazacyclopenta[m]tetraphenes

ChemistryOpen (Weinheim), 2023-03, Vol.12 (3), p.e202300009-n/a

2023

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Synthesis, Cytotoxicity, Antimicrobial and Docking Simulation of Novel Pyrazolo[3,4-d]pyrimidine and pyrazolo[4,3-e][1,2,4]triazolo[3,4-c] pyrimidine Derivatives

Mini reviews in medicinal chemistry, 2019-01, Vol.19 (8), p.657-670

2019

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Synthesis of Novel Diphenyl Ether-Based Bis-Heterocycles as Novel Hybrid Molecules via Michael and Other Cyclocondensation Reactions

ACS omega, 2024-01, Vol.9 (3), p.4073-4084

2024

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Chalcones: Promising therapeutic agents targeting key players and signaling pathways regulating the hallmarks of cancer

Chemico-biological interactions, 2023-01, Vol.369, p.110297-110297, Article 110297

2023

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Synthesis, characterization and antimicrobial activity of a novel chitosan Schiff bases based on heterocyclic moieties

International journal of biological macromolecules, 2020-06, Vol.153, p.492-501

2020

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Cytotoxicity, molecular modeling, cell cycle arrest, and apoptotic induction induced by novel tetrahydro-[1,2,4]triazolo[3,4-a]isoquinoline chalcones

European journal of medicinal chemistry, 2018-01, Vol.143, p.532-541

2018

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[1,2,4] Triazolo [3,4-a]isoquinoline chalcone derivative exhibits anticancer activity via induction of oxidative stress, DNA damage, and apoptosis in Ehrlich solid carcinoma-bearing mice

Naunyn-Schmiedeberg's archives of pharmacology, 2022-10, Vol.395 (10), p.1225-1238

2022

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Enamines as Precursors to Polyfunctional Heteroaromatic Compounds; a Decade of Development

Heterocycles, 2008-08, Vol.75 (8), p.1849

2008

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Synthesis of novel chitosan-Schiff bases nanoparticles for high efficiency Helicobacter pylori inhibition

International journal of biological macromolecules, 2024-08, Vol.274 (Pt 2), p.133499, Article 133499

2024

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Novel 2‐cyanoacrylamido‐4,5,6,7‐tetrahydrobenzo[b]thiophene derivatives as potent anticancer agents

Archiv der Pharmazie (Weinheim), 2020-10, Vol.353 (10), p.e2000069-n/a

2020

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Novel 3-(pyrazol-4-yl)-2-(1H-indole-3-carbonyl)acrylonitrile derivatives induce intrinsic and extrinsic apoptotic death mediated P53 in HCT116 colon carcinoma

Yttrium Oxide nanoparticles induce cytotoxicity, genotoxicity, apoptosis, and ferroptosis in the human triple-negative breast cancer MDA-MB-231 cells

Synthesis of novel acridines, tetrahydrodipyrazolo [3,4-b:4',3'-e]pyridines, tri-substituted methanes (TRSMs) bearing 2-(4-(1-phenyl-1H-pyrazol-3-yl)phenoxy)-N-phenylacetamide unit as novel hybrid molecules

DNA Fragmentation, Cell Cycle Arrest, and Docking Study of Novel Bis Spiro-cyclic 2-oxindole of Pyrimido[4,5-b]quinoline-4,6-dione Derivatives Against Breast Carcinoma

Synthetic Routes to Spirocyclic Pyridazines, Partially-Saturated Pyridazines and Their Condensed Derivatives

Novel Tetrahydro-[1,2,4]triazolo[3,4- a ]isoquinoline Chalcones Suppress Breast Carcinoma through Cell Cycle Arrests and Apoptosis

An overview on synthetic strategies for the construction of star-shaped molecules

Multicomponent Synthesis of Novel bis(2-amino-tetrahydro-4H-chromene-3- carbonitrile) Derivatives Linked to Arene or Heteroarene Cores

Synthesis, Cytotoxicity and Molecular Docking Simulation of Novel bis-1,4-Dihydropyridines Linked to Aliphatic or Arene Core via Amide or Ester-Amide Linkages

Novel thiazole-based cyanoacrylamide derivatives: DNA cleavage, DNA/BSA binding properties and their anticancer behaviour against colon and breast cancer cells

Microwave Assisted Multi-Component Synthesis of Novel Bis(1,4-dihydropyridines) Based Arenes or Heteroarenes

Novel Scaffolds Based on Bis-thiazole Connected to Quinoxaline or Thienothiophene through 2-Phenoxy- N -arylacetamide Groups as New Hybrid Molecules: Synthesis, Antibacterial Activity, and Molecular Docking Investigations

Utility of 2‑Chloro‑N‑arylacetamide and 1,1′-(Piperazine-1,4-diyl)bis(2-chloroethanone) as Versatile Precursors for Novel Mono- and Bis[thienopyridines]

Biological Activities and Docking Studies on Novel Bis 1,4-DHPS Linked to Arene Core via Ether or Ester Linkage

Novel hybrid thiazoles, bis-thiazoles linked to azo-sulfamethoxazole: Synthesis, docking, and antimicrobial activity

New Azacycles by One‐Pot Three‐Component Hantzsch‐Like Synthesis of Tetra(hexa)azacyclopenta[a]anthracenes, Tetraazaindeno[5,4‐b]fluorenes, and Oxatetraazacyclopenta[m]tetraphenes

Synthesis, Cytotoxicity, Antimicrobial and Docking Simulation of Novel Pyrazolo[3,4-d]pyrimidine and pyrazolo[4,3-e][1,2,4]triazolo[3,4-c] pyrimidine Derivatives

Synthesis of Novel Diphenyl Ether-Based Bis-Heterocycles as Novel Hybrid Molecules via Michael and Other Cyclocondensation Reactions

Chalcones: Promising therapeutic agents targeting key players and signaling pathways regulating the hallmarks of cancer

Synthesis, characterization and antimicrobial activity of a novel chitosan Schiff bases based on heterocyclic moieties

Cytotoxicity, molecular modeling, cell cycle arrest, and apoptotic induction induced by novel tetrahydro-[1,2,4]triazolo[3,4-a]isoquinoline chalcones

[1,2,4] Triazolo [3,4-a]isoquinoline chalcone derivative exhibits anticancer activity via induction of oxidative stress, DNA damage, and apoptosis in Ehrlich solid carcinoma-bearing mice

Enamines as Precursors to Polyfunctional Heteroaromatic Compounds; a Decade of Development

Synthesis of novel chitosan-Schiff bases nanoparticles for high efficiency Helicobacter pylori inhibition

Novel 2‐cyanoacrylamido‐4,5,6,7‐tetrahydrobenzo[b]thiophene derivatives as potent anticancer agents

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