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Dual IGF-I/II-Neutralizing Antibody MEDI-573 Potently Inhibits IGF Signaling and Tumor Growth

Cancer research (Chicago, Ill.), 2011-02, Vol.71 (3), p.1029-1040

2011

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Circulating Insulin-Like Growth Factors and IGF-Binding Proteins in PSA-Detected Prostate Cancer: The Large Case-Control Study ProtecT

Cancer research (Chicago, Ill.), 2012-01, Vol.72 (2), p.503-515

2012

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A Meta-analysis of Individual Participant Data Reveals an Association between Circulating Levels of IGF-I and Prostate Cancer Risk

Cancer research (Chicago, Ill.), 2016-04, Vol.76 (8), p.2288-2300

2016

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Targeting IGF Perturbs Global Replication through Ribonucleotide Reductase Dysfunction

Cancer research (Chicago, Ill.), 2021-04, Vol.81 (8), p.2128-2141

2021

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β-Catenin/POU5F1/SOX2 transcription factor complex mediates IGF-I receptor signaling and predicts poor prognosis in lung adenocarcinoma

Cancer research (Chicago, Ill.), 2013-05, Vol.73 (10), p.3181-3189

2013

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Bone-Derived IGF Mediates Crosstalk between Bone and Breast Cancer Cells in Bony Metastases

Cancer research (Chicago, Ill.), 2012-08, Vol.72 (16), p.4238-4249

2012

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A Kinome-Wide Screen Identifies the Insulin/IGF-I Receptor Pathway as a Mechanism of Escape from Hormone Dependence in Breast Cancer

Cancer research (Chicago, Ill.), 2011-11, Vol.71 (21), p.6773-6784

2011

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Reduced Levels of IGF-I Mediate Differential Protection of Normal and Cancer Cells in Response to Fasting and Improve Chemotherapeutic Index

Cancer research (Chicago, Ill.), 2010-02, Vol.70 (4), p.1564-1572

2010

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Abstract 729: Novel role of CB2R in tuning breast tumor microenvironment, EGF/EGFR and IGF-I/IGF-IR pathways

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.729-729

2016

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Plasma insulin-like growth factor (IGF) I, IGF-binding protein 3, and mammographic density

Cancer research (Chicago, Ill.), 2000-07, Vol.60 (14), p.3744-3748

2000

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A chimeric humanized single-chain antibody against the type I insulin-like growth factor (IGF) receptor renders breast cancer cells refractory to the mitogenic effects of IGF-I

Cancer research (Chicago, Ill.), 2003-02, Vol.63 (3), p.627-635

2003

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IGF-I Regulates Redox Status in Breast Cancer Cells by Activating the Amino Acid Transport Molecule xC

Cancer research (Chicago, Ill.), 2014-04, Vol.74 (8), p.2295-2305

2014

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Targeting Quiescent Tumor Cells via Oxygen and IGF-I Supplementation

Cancer research (Chicago, Ill.), 2012-02, Vol.72 (3), p.801-809

2012

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Dsh homolog DVL3 mediates resistance to IGFIR inhibition by regulating IGF-RAS signaling

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (20), p.5866-5877

2014

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Abstract P3-10-09: Gene deletion of IRS1 inhibited IGF-I, insulin and estradiol stimulated MCF-7L breast cancer cell growth

Cancer research (Chicago, Ill.), 2020-02, Vol.80 (4_Supplement), p.P3-P3-10-09

2020

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Insulin-like growth factor I (IGF-I) and the IGF-I receptor prevent etoposide-induced apoptosis

Cancer research (Chicago, Ill.), 1995-01, Vol.55 (2), p.303-306

1995

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Abstract ES9-1: Role for IGF/Insulin signaling in breast cancer

Cancer research (Chicago, Ill.), 2016-02, Vol.76 (4_Supplement), p.ES9-1-ES9-1

Yee, D

2016

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Abstract B04: Oncogenic relevance of IGF-IR and PI3K/AKT/GSK3-beta signaling in myxoid liposarcoma

Cancer research (Chicago, Ill.), 2017-11, Vol.77 (22_Supplement), p.B04-B04

2017

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Abstract 5881: Identification of resistance mechanisms to IGF-IR targeting in triple negative breast cancer

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.5881-5881

2017

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Abstract CT086: Treatment of ductal carcinoma in situ (DCIS) with pasireotide, an IGF-I inhibitor

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.CT086-CT086

2017

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Abstract 4132: ASO screen uncovers splicing as a therapeutic vulnerability in theinsulin-like growth factor (IGF) signaling pathway

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.4132-4132

2018

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Abstract 4813: Enhancement of nab-paclitaxel response by inhibition of insulin-like growth factor (IGF) signaling in experimental esophageal adenocarcinoma

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.4813-4813

2018

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Abstract 609: Targeting IGF-I receptor for hepatocellular carcinoma

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.609-609

2014

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Abstract 3006: Serum insulin growth factor/insulin growth factor receptor1 (IGF-I, IGF-I-1R) and VEGF-A as prognostic factors and surrogate biomarkers in triple negative breast cancer patients (TNBC)

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.3006-3006

2014

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Bimolecular Interaction of Insulin-Like Growth Factor (IGF) Binding Protein-2 with alpha v beta 3 Negatively Modulates IGF-I-Mediated Migration and Tumor Growth

Cancer research (Chicago, Ill.), 2004-02, Vol.64 (3), p.977-984

2004

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Dual IGF-I/II-Neutralizing Antibody MEDI-573 Potently Inhibits IGF Signaling and Tumor Growth

Circulating Insulin-Like Growth Factors and IGF-Binding Proteins in PSA-Detected Prostate Cancer: The Large Case-Control Study ProtecT

A Meta-analysis of Individual Participant Data Reveals an Association between Circulating Levels of IGF-I and Prostate Cancer Risk

Targeting IGF Perturbs Global Replication through Ribonucleotide Reductase Dysfunction

β-Catenin/POU5F1/SOX2 transcription factor complex mediates IGF-I receptor signaling and predicts poor prognosis in lung adenocarcinoma

Bone-Derived IGF Mediates Crosstalk between Bone and Breast Cancer Cells in Bony Metastases

A Kinome-Wide Screen Identifies the Insulin/IGF-I Receptor Pathway as a Mechanism of Escape from Hormone Dependence in Breast Cancer

Reduced Levels of IGF-I Mediate Differential Protection of Normal and Cancer Cells in Response to Fasting and Improve Chemotherapeutic Index

Abstract 729: Novel role of CB2R in tuning breast tumor microenvironment, EGF/EGFR and IGF-I/IGF-IR pathways

Plasma insulin-like growth factor (IGF) I, IGF-binding protein 3, and mammographic density

A chimeric humanized single-chain antibody against the type I insulin-like growth factor (IGF) receptor renders breast cancer cells refractory to the mitogenic effects of IGF-I

IGF-I Regulates Redox Status in Breast Cancer Cells by Activating the Amino Acid Transport Molecule xC

Targeting Quiescent Tumor Cells via Oxygen and IGF-I Supplementation

Dsh homolog DVL3 mediates resistance to IGFIR inhibition by regulating IGF-RAS signaling

Abstract P3-10-09: Gene deletion of IRS1 inhibited IGF-I, insulin and estradiol stimulated MCF-7L breast cancer cell growth

Insulin-like growth factor I (IGF-I) and the IGF-I receptor prevent etoposide-induced apoptosis

Abstract ES9-1: Role for IGF/Insulin signaling in breast cancer

Abstract B04: Oncogenic relevance of IGF-IR and PI3K/AKT/GSK3-beta signaling in myxoid liposarcoma

Abstract 5881: Identification of resistance mechanisms to IGF-IR targeting in triple negative breast cancer

Abstract CT086: Treatment of ductal carcinoma in situ (DCIS) with pasireotide, an IGF-I inhibitor

Abstract 4132: ASO screen uncovers splicing as a therapeutic vulnerability in theinsulin-like growth factor (IGF) signaling pathway

Abstract 4813: Enhancement of nab-paclitaxel response by inhibition of insulin-like growth factor (IGF) signaling in experimental esophageal adenocarcinoma

Abstract 609: Targeting IGF-I receptor for hepatocellular carcinoma

Abstract 3006: Serum insulin growth factor/insulin growth factor receptor1 (IGF-I, IGF-I-1R) and VEGF-A as prognostic factors and surrogate biomarkers in triple negative breast cancer patients (TNBC)

Bimolecular Interaction of Insulin-Like Growth Factor (IGF) Binding Protein-2 with alpha v beta 3 Negatively Modulates IGF-I-Mediated Migration and Tumor Growth

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